山西省草蛉一新种(脉翅目:草蛉科)

作者在对本所馆藏草蛉标本进行整理鉴定中,发现一新种。属草蛉科(Chrysopidae)纳革蛉属(Navasius Yang et Yang),因新种采自山西省盂县境内,故定名为盂县纳草蛉(Navasius yuxianensis sp.nov.)。模式标本保存在山西省农业科学院植物保护研究所标本室。     

中国粉蛉属四种雌虫的分类学研究(脉翅目:粉蛉科)

对粉蛉科雌虫的分类研究方法进行了初步摸索,并对阿氏粉蛉Coniopteryx(Coniopteryx)aspoecki Kis,1967、圣洁粉蛉Coniopteryx(Coniopteryx)pygmaea Enderlein,1906、斜突粉蛉 Coniopteryx(Coniopteryx)plagiotropa Liu et Yang, 1997、周氏粉蛉Coniopteryx (Coniopteryx) choui Liu et Yang,1998的雌虫内生殖器结构特征进行了描述和绘图。     

中国边草蛉属研究(脉翅目,草蛉科)

检视和记述了我国边草蛉属Brinckochrysa Tieder 5个种类(包括1新种):桂边草蛉Brinckochrysa guiana sp.nov,琼边草蛉B.qwngana Yang,莲座边草蛉B.rosulataYang et Yang,膨板边草蛉B.turgida(Yang et Wang,1990)和秉氏边草蛉B.zina(Navas,1933),新种有详细的形态学描述、插图、种名词源以及与其近似种的区别.所有模式标本保存于中国农业大学标本馆.桂边草蛉,新种Brinckochrysa guianasp.nov.正模♂,广西临桂县,150 m,1963-04-29,杨集昆采.     

中国边草蛉属研究（脉翅目，草蚜科）

检视和记述了我国边草蛉属Brinckochrysa Tjeder 5个种类（包括1新种）;桂边草蛉Brinckochrysa guiana sp.nov,琼边草蛉B.qionguna Yang,莲座边草蛉B.rasulata Yang et Yang,膨板边草蛉B.turgida(yang et Wang,1990)和秉氏边草蛉B.zina(Navas,1933),新种有详细的形态学描述、插图、种名词源以及与其近似种的区别。所有模式标本保存于中国农业大学标本馆。     

中国树蚁蛉属分类研究(脉翅目,蚁蛉科)

记述了中国蚁蛉科树蚁蛉属Dendroleon 5种,其中包括3新种:丽翅树蚁蛉Dendroleon callipterum Wan et Yang,sp.nov.,李氏树蚁蛉Dendroleon lii Wan et Wang,sp.nov.,珠斑树蚁蛉Dendroleon perlistigma Wan et Wang,sp.nov..模式标本保存在中国农业大学昆虫标本馆.     

温度对白面叉草蛉发育与繁殖的影响

白面叉草蛉Dichochrysa albofrontata Yang et Yang是螺旋粉虱Aleurodicus dispersus RusseⅡ的重要捕食性天敌.本文在实验室温(26℃～32℃)及特设(16℃、20℃、24℃、28℃、32℃)下对白面叉草蛉的发育及繁殖情况进行了研究.结果表明:白面叉草蛉发育经历卵...     

云南省粉蛉两新种记述（脉翅目：粉蛉科）

记述云南省脉翅目粉岭科2新种：奇斑曲粉岭Coniocom psa spectabilis Liu et yang,sp.nov和丫重粉蛉Semidalis ypsilon Liu et Yang,sp.nov。。模式标本均保存在中国农业大学昆虫标本馆。     

辽宁北票晚侏罗世丽蛉化石二新属(脉翅目,丽蛉科)

描述丽蛉科化石2新属2新种：美形山丽蛉oregramma gloriosa gen.et sp.nov.,奇异沼泽丽蛉Limnogramma mira gen.et sp.nov.。标本采自辽宁省北票市晚侏罗世义县组地层中。模式标本保存在首都师范大学生物系。     

中国棘蚁蛉族分类研究(脉翅目,蚁蛉科)

对中国棘蚁蛉族Acanthaclisini进行了分类研究和修订,共记述中国棘蚁蛉族4属5种(包括2新纪录属、2新纪录种):尾棘蚁蛉Acanthaclisis pallida Mclachlan,单中大蚁蛉Centroclisis negligens(Navás),南击大蚁蛉Heoclisis kawaii(Nakahara),追击大蚁蛉Heoclisis japonica(Maclachlan)和黎母硕蚁蛉Stiphroneura inclusa(Walker).其中棘蚁蛉属Acanthaclisis和硕蚁蛉属Stiphroneura为中国新纪录属,尾棘蚁蛉A.pallida Mclachlan和黎母硕蚁蛉S.inclusa(Walker)为中国新纪录种.确定了Alloclisis hainanica Yang为Centro-clisis negligens(Navás)的新异名,Neriga limoiana Yang为Stiphroneura inclusa(Walker)的新异名.编写了中国棘蚁蛉族分种检索表.标本保存在中国农业大学昆虫系标本馆和中国科学院动物所.     

普通齿蛉和单斑巨齿蛉(广翅目:齿蛉科)卵块及1龄幼虫形态学研究

本文以普通齿蛉Neoneuromus ignobilis Navás,1932和单斑巨齿蛉Acanthacorydalis unimaculata Yang et Yang,1986为例,描述和比较了广翅目齿蛉科齿蛉属和巨齿蛉属的卵块及1龄幼虫形态特征.结果显示普通齿蛉与单斑巨齿蛉的卵块和1龄幼虫在形态上有着较大差异:普通齿蛉卵块约为单斑巨齿蛉卵块的3/4;普通齿蛉卵粒约为单斑巨齿蛉卵粒的2/3,卵粒都呈圆柱形,差异不大;普通齿蛉外层白色覆盖物厚度是单斑巨齿蛉的2～3倍.普通齿蛉卵块为单个附着在芦苇叶上,形状有4种类型,分别为椭圆形、螺形、卵圆形、圆形,在所有样本中其占比分别依次为47.1％、9.8％、17.6％和25.5％;单斑巨齿蛉卵块多为数个相连附着在桥底,卵壳薄且最外层卵粒向外翘起,使其表面如突起均匀地分布在卵壳表面.普通齿蛉1龄幼虫腹部背面白色的线状裸露区较稳定,且8对气管鳃靠近末端都有褐色和黄色的斑纹,而单斑巨齿蛉1龄幼虫腹部背面呈深褐色,腹部背面裸露区和颜色分布不稳定,气管鳃无花斑;两种1龄幼虫腹部两侧均都无毛簇.这些数据资料不仅丰富了广翅目昆虫的相关知识,而且为其产业化应用提供了参考.     

Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis

It has now been over twenty years since a novel herpesviral genome was identified in Kaposi's sarcoma biopsies. Since then, the cumulative research effort by molecular biologists, virologists, clinicians, and epidemiologists alike has led to the extensive characterization of this tumor virus, Kaposi's sarcoma-associated herpesvirus(KSHV; also known as human herpesvirus 8(HHV-8)), and its associated diseases. Here we review the current knowledge of KSHV biology and pathogenesis, with a particular emphasis on new and exciting advances in the field of epigenetics. We also discuss the development and practicality of various cell culture and animal model systems to study KSHV replication and pathogenesis.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

Microbial resistance to antibiotics is an unresolved global concern, which needs urgent and coordinated action. One of the guidelines of the Centers for Disease Control and Preventions (CDC) to combat antibiotic resistance is the development of new antibiotics to treat drug-resistant bacteria. In our effort to find new antibiotics, we report the synthesis and antimicrobial studies of 30 new pyrazole derivatives. These novel molecules have been synthesized by using readily available starting materials and benign reaction conditions. Some of these molecules have shown activity with MIC values as low as 0.78?µg/mL against four bacterial strains; Staphylococcus aureus, methicillin-resistant S. aureus, Bacillus subtilis, and Acinetobacter baumannii. Furthermore, active molecules are non-toxic to mammalian cell line.

     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Novel compounds with potent CDK9 inhibitory activity for the treatment of myeloma

Cyclin-dependent kinases (CDKs) and Polo-like kinases (PLKs) play key role in the regulation of the cell cycle. The aim of our study was originally the further development of our recently discovered polo-like kinase 1 (PLK1) inhibitors. A series of new 2,4-disubstituted pyrimidine derivatives were synthesized around the original hit, but their PLK1 inhibitory activity was very poor. However the novel compounds showed nanomolar CDK9 inhibitory activity and very good antiproliferative effect on multiple myeloma cell lines (RPMI-8226).