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培养学生的创新能力与实践能力是现代大学教育的共同教育理念。根据多年来微生物学实验教学的改革与实践,对实验内容进行了精心的调整、完善和更新,按"基本技能训练、综合能力培养、研究素质及创新意识培育"的基本宗旨,构建了从"综合实验—探究性自选实验—项目申报"的微生物创新实验教学体系,使实验教学遵循基础性、综合性、研究性、开放性的基本原则,有效提高学生的微生物学实验技能。 相似文献
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本科微生物学实验教学改革初探 总被引:9,自引:0,他引:9
微生物学是一门实验性很强的学科,加强实验教学改革对于培养学生的综合素质和创新精神具有重要意义。从实验内容选取,微生物实验教学方法和教学手段改革等三个方面,提出了实验教学改革的一些设想,目的在于提高实验教学质量,培养创新型人才。 相似文献
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实施“三高”教学,创建“微生物学实验”课程新体系 总被引:21,自引:1,他引:21
深化微生物实验教学改革,实施“高起点、高效率、高质量”教学,从调整教学内容,改革教学方法,建立和完善考评机制入手,创建“以基础知识和基本技能为基础性内容,以创新能力培养为核心内容”的微生物学实验课程新体系,激发了学生对微生物学实验的兴趣,培养了学生独立思考、创新思维和综合动手的能力。 相似文献
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"食品微生物学"是高等院校食品科学与工程、食品质量与安全及其相关专业的一门必修专业基础课,该课程实验技术是食品类专业学生必须掌握的基本技能,而传统的实验教学存在着与就业岗位需求脱节、学生参与度低等诸多问题,难以培养学生独立完成岗位工作的能力。为了培养学生的综合实践能力,适应就业岗位需求,保证该课程的实践教学质量,课题组通过调研30余家就业单位微生物岗位实际,将课程原有实验教学内容整合为两大综合性实验项目,涵盖了食品微生物学全部基本实验技能。实践表明,两大综合性实验项目的开展可有效提高食品微生物学实验教学效果,使学生全面获得食品微生物学的基本实验技能,有助于提高学生的综合能力,实现学生与就业岗位的无缝对接。 相似文献
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项目式“微生物学实验”教学模式的构建与实践 总被引:1,自引:1,他引:0
微生物学实验是生物类各专业的一门重要的专业基础课程,微生物学实验技术是学生认识微生物、改造微生物和利用微生物的重要方法。课程组结合优质教学资源,以及先进仪器设备和网络技术的助力加持,构建了项目式"微生物学实验"教学模式。通过项目实验的科学设计、实施和评价,对实验教学进行了一系列的改革实践与探索,提高了实验教学效果和效率,使学生对微生物学研究有了更系统的认识,对培养学生的综合实践能力和科学研究思维起到了积极有效的促进作用。 相似文献
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Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme
responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare
the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show
that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by
distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of
demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least
one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of
the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable
potent antiproliferative synthetic drugs. 相似文献
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正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases 相似文献
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The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle. 相似文献
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鸡传染性法氏囊病病毒研究进展 总被引:3,自引:0,他引:3
传染性法氏囊病(Infection bursal disease, IBD)是由鸡传染性法氏囊病毒(Infectious bursal disease virus, IBDV)引起的鸡和火鸡的一种高度接触性传染病,给世界各国的禽养殖业带来了巨大损失.自IBDV发现至今新的变异株不断出现,分子结构的改变导致病毒致病力的改变及宿主对疫苗应答的改变,使得传统的疫苗已不能控制其流行,因此各国学者对其基因组结构和功能进行了广泛深入的研究,并积极研制新型有效的疫苗以达到防治的目的. 相似文献
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Renfei Lu Xiuming Wu Zhenzhou Wan Yingxue Li Lulu Zuo Jianru Qin Xia Jin Chiyu Zhang 《中国病毒学》2020,35(3):344-347
In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans. 相似文献
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Shen Jia-Yuan Li Man Xie Lyu Mao Jia-Rong Zhou Hong-Ning Wang Pei-Gang Jiang Jin-Yong An Jing 《中国病毒学》2021,36(1):145-148
正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016). 相似文献
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Meng Miao Gang Deng Xiaobei Xiong Yang Qiu Wenda Huang Meng Yuan Fei Yu Shimei Bai Xi Zhou Xiaolu Zhao 《中国病毒学》2022,37(2):314-317
Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions. 相似文献
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions. 相似文献