“发酵工程”课程思政教学改革的探索与实践

课程思政是当前高校大学生思想政治教育的新理念和新模式,其核心思想是将高校思想政治教育融入各类课程教学中。我们在"发酵工程"课程教学中,通过提升任课教师的课程思政能力,探索在课程绪论、课程知识点、历史故事、社会热点、实验实训中融入思政元素,力求实现"教书"与"育人"的统一。     

自然科学课程思政的教学探索——以微生物学为例

课程思政是近年来在我国高校广泛推广的一种新的教学理念,其核心思想是将高校思想政治教育融入到各类课程教学之中。高校课程可以分为思想政治课程、通识教育课程、哲学社会科学课程、自然科学课程,其中自然科学课程与思政教育关系最为松散,思政元素的融入也最为困难。本文从微生物学融入课程思政的教学实践出发,分析高校自然科学类课程实施课程思政的必要性及难点,探索思政资源的挖掘路径,通过调查研究评估课程思政的教学效果,以及对课程思政的实践进行教学反思。此外,对专业课教师关于课程思政的观点分歧也做了初步探讨。本文旨在为微生物学相关课程实施课程思政提供理论支撑、实证数据以及教学经验,并可为其他自然科学类课程参鉴。     

“微生物学与免疫学”课程思政的探索与实践

"微生物学与免疫学"是药学、农学、生物学等生命科学相关学科的基础核心课程,也是当今世界发展最为迅猛、对人类生活影响最大的学科之一。高校为达到"立德树人"的教育根本任务,应将微生物学与免疫学课程建设成为思政教育的重要阵地。将我国科学家的突出科学贡献、教材知识点以及相应的思政内容有机整合,实现巩固知识、强化专业教学,加强思政教育,达到"立德树人"的培养目标。本文介绍了以我国科学家的案例进行微生物学与免疫学课程思政教学的探索和实践,将典型案例融入到教材知识点中有利于课程思政的建设。     

“海洋微生物学实验”课程思政探索和实践

"海洋微生物学实验"课程是高等院校海洋科学类专业的重要基础课程,在海洋科学人才培养过程中发挥重要作用。开展"海洋微生物学实验"课程的思政建设,是落实高校全员全程全方位培养青年海洋微生物人才的重要途径。本文以"海洋微生物学实验"课程为例,挖掘提炼课程中蕴含的思政元素,从课程建设、教学理念、教学目标、教学方法、考核评价体系、教学反思等方面开展课程思政教育的探索和实践,旨在将专业知识和思政元素有机融合,实现知识传授和价值引领同频共振。     

高校专业基础课程“微生物学”思政案例设计

为充分挖掘微生物学课程中的思政元素,发挥专业课程在立德树人方面的重要作用,本文对微生物学课程思政的设计理念和具体案例进行介绍,构建以微生物学知识为主体,以发展历史、名人故事、励志典故、日常生活等为素材,将专业知识和思政教育融合,引导学生树立辩证思维,端正学生求真求实的科学态度,增强学生社会责任感,实现"全员育人、全程育人、全方位育人"的创新教育模式。     

微生物课程中思政元素的挖掘与应用

作为一种新的综合教育理念和课程观,课程思政是高校培养德智体美全面发展的社会主义建设者和接班人的必然之举.文章就课程思政在"微生物学"课程中的教学实践,从专业课程中进行课程思政的重要性、微生物学专业课中课程思政元素的挖掘以及如何将思想政治教育在微生物学课程中有效实施进行了探讨,以确保以微生物学教学目标为立足点,自然恰当地...     

食品微生物学课程思政探索与实践

课程思政作为一种新的教学理念,近年来被广泛推崇。其核心在于将思政教育融入教学实践活动中,提倡一种"隐形教育"。本文从课程思政的现状入手,分析了思政教育融入"食品微生物学"课程的必要性,重点论述了思政元素的挖掘途径。通过将教材知识点与思政教育有机结合,实现巩固知识、加强思政教育的目的,培养学生的科学精神、人文精神,实现民族文化自信。食品微生物学作为食品科学与工程专业的核心课程,要求理论联系实际。本文通过调查研究总结该课程的实践成效,探索该课程思政教育的专业知识切入点,并为后续食品专业课程思政的有效教学途径进行更深层次的探索提供参考。     

“工业微生物”课程思政元素引入及评价

把立德树人作为中心,把思政工作贯穿全程是新时期高等教育的重要使命。课程思政元素引入是当前高校教育实现"立德树人"根本任务的重要观念与方法。通过问卷调查方式,从学生层面了解到高校教育课程思政建设的重要性及需求必要性。在课程实施思政建设过程中,以经典案例为依托,结合课程实际知识点,融入思政元素,并通过改革教学方式方法,实现课程思政功能。案例与课程应具有较强相关性,且必须典型。思政元素应多元、有效、智趣,且亲和性突出。因此,高校专业课程应有效融合不同教学方法,引入恰当有趣的思政元素,高效实现课程思政功能,达到课程育人的目的。     

“环境工程微生物学”课程思政实践举措

课程思政在高校实现“三全育人”体系中发挥着重要的作用，是当前高校教学改革研究的热点之一。本文以环境工程专业“环境工程微生物学”课程为例，首先从课程思政元素发掘、提升教师课程思政能力、培养学生学习兴趣和重要保障等四方面对该课程思政开展具体实践；其次从提升学生课程思政理念、提高学生课程成绩及对全校课程思政的引领等方面展现课程思政的实践成效；最后结合教学实践对课程思政进行了讨论和展望。通过上述研究，以期为环境工程专业课程思政改革提供实践路径，为发挥专业课的育人机制提供参考。     

金课背景下涉农高校生物化学课程思政教学的探索与实践

金课背景下,课程思政建设是涉农高校实现立德树人根本任务的重要抓手,是我国加快实现农业强国的必经之路,也是我国全面建设社会主义现代化国家、全面推进中华民族伟大复兴的必然要求。生物化学是一门与生命和生活息息相关的专业基础课程,具有较强的理论性和实践性,蕴含丰富的思政教育元素,具有良好的育人价值与育才潜力,是思政元素融入的有效载体。本文以生物化学课程为例,积极响应涉农高校将思政教育融入专业课教学、发挥专业课思政教育功能的党中央号召,先后进行了课程思政素材挖掘、育人案例筛选、教学方案设计、教学活动实施、教学评价反思等的探索和实践,旨在建立符合《高等学校课程思政建设指导纲要》要求的教学模式,进而实现生物化学课程教学质量的持续改进和大力提升。     

Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis

It has now been over twenty years since a novel herpesviral genome was identified in Kaposi's sarcoma biopsies. Since then, the cumulative research effort by molecular biologists, virologists, clinicians, and epidemiologists alike has led to the extensive characterization of this tumor virus, Kaposi's sarcoma-associated herpesvirus(KSHV; also known as human herpesvirus 8(HHV-8)), and its associated diseases. Here we review the current knowledge of KSHV biology and pathogenesis, with a particular emphasis on new and exciting advances in the field of epigenetics. We also discuss the development and practicality of various cell culture and animal model systems to study KSHV replication and pathogenesis.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

Microbial resistance to antibiotics is an unresolved global concern, which needs urgent and coordinated action. One of the guidelines of the Centers for Disease Control and Preventions (CDC) to combat antibiotic resistance is the development of new antibiotics to treat drug-resistant bacteria. In our effort to find new antibiotics, we report the synthesis and antimicrobial studies of 30 new pyrazole derivatives. These novel molecules have been synthesized by using readily available starting materials and benign reaction conditions. Some of these molecules have shown activity with MIC values as low as 0.78?µg/mL against four bacterial strains; Staphylococcus aureus, methicillin-resistant S. aureus, Bacillus subtilis, and Acinetobacter baumannii. Furthermore, active molecules are non-toxic to mammalian cell line.

     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.