山东汉族成人的Heath-Carter法体型研究

应用HeathCarter人体测量法对1001名（男502名,女499名）年龄在20—88岁间的山东省青州和临朐两县市的城乡汉族（以下简称山东汉族）进行了体型评定。结果是：（1）山东汉族男性的平均体型值为44—48—17（城4.6—4.7—1.5,乡4.2—4.8—1.8）,属内胚层-中胚层均衡型体型;各年龄组中以内胚层-中胚层均衡体型、偏内胚层的中胚层体型及偏中胚层的内胚层体型为主。女性的平均体型值为5.7—4.2—1.4（城5.8—4.2—1.3,乡5.6—4.2—1.4）,属偏中胚层的内胚层体型;各年龄组中以偏中胚层的内胚层体型及内胚层-中胚层均衡体型为主。（2）随着年龄的增长,男（20—44岁）女（20—54岁）性内、中因子值上升,外因子值下降。城乡男女以30岁为体型分界点,表现为30岁前后的体型差异。（3）汉族成年人体型存在显著性性别差异,但无城乡差异。（4）山东汉族男性与蒙古族及加拿大样本人群的平均体型相类似;女性平均体型介于鄂温克族、鄂伦春族、达斡尔族和蒙古族样本人群的平均体型之间。     

乌孜别克族成人的体型特点

目的：了解乌孜别克族成人的体型特点。方法：运用HeathCarter体型法对201名（男110,女91）乌孜别克族成人体型进行分析。结果：乌孜别克族男性为偏内胚层的中胚层型体型（3.7—5.1—2.0）,女性为偏中胚层的内胚层型体型（5.9—4.9—1.4）。60岁之前随年龄增长,男女性均呈内、中因子值上升而外因子值下降的趋势,二者体型的性别差异极显著。与其他群体相比,乌孜别克族女性的中因子成分明显占优,男性平均体型则与加拿大人最相似。结论：乌孜别克族成年男女的体格都比较健壮。     

达斡尔族青少年体型的Heath—Carter人体测量法研究

运用Heath-Carter人体测量法对1759例（男872,女887）6－19岁达斡尔族青少年体型进行了研究。结果表明：（1）男生6－8岁各组为均衡的中胚层体型,9－12岁各组为三胚层中间型体型,13－17岁各组为中胚层－外胚怪均衡型体型。女生7－12岁各组为三胚层中间型体型,13－14岁各组为均衡的内胚层体型,15－19岁各组为偏中胚层的内胚层体型。（2）男女生6－9岁中胚层体型比例最高,10－12岁外胚层体型比例最高。男生13－16岁仍为外胚层体型比较最高。女生13－15岁、16－19岁均为内胚层体型比例最高。（3）达斡尔族男女生体型与蒙古族体型接近。     

侗族成人Heath-Carter法体型研究

为探讨我国侗族成人的体型特征,本文采用Heath-Carter人体测量法对广西壮族自治区三江侗族自治县林溪乡515例（男254,女261）20—60岁的土著侗族成人进行了体型评定。结果表明：1）侗族成人男女的平均体型值分别为2.2—4.5—2.4和4.3—4.2—1.5,侗族成人男女分别属均衡的中胚层体型和内胚层—中胚层均衡体型;2）侗族成人男女间SAD值为2.33,T为11.9,男女间的体型有非常显著性差异（P<0.001) ;3) 与国内 、外资料相比, 侗族男女的内、中因子值和男性外因子值居中, 女性外因子值最低。     

蒙古族青少年体型的研究——运用Heath—Carter体型法

运用Ｈｅａｔｈ－Ｃａｒｔｅｒ体型法对１５６４名（男７２３,女８４１）７－１９岁蒙古族青少年体型进行了研究。结果表明蒙古族青少年体型随年龄增长而变化。男性平均体型变化较小。女性较大。男性以中胚层体型和偏中胚层体型的外胚层体型为主;女性随年龄增长逐渐从中间体型向偏中胚层体型的内胚层体型过渡。经检验从１１岁以后男女性的平均体型具有显著性差异。通过与其他群体青少年平均体型的比较,表明在不同民族,种族间的体     

鄂温克族成人的Heath-Carter法体型研究

用Ｈｅａｔｈ－Ｃａｒｔｅｒ人体测量法对３５７名（男１６２,女１９５）２０～６０岁的鄂温克族进行了体型平定。鄂温克族男女的平均体型值为３．５～５．０－、．６和５．２、４．４－１．５,分别属内胚层的中胚层体型和偏中胚层的内胚层体型。２０～４４岁期间,随着年龄的增长,鄂温克族男女存在着内、中因子值上升和外因子值理降的趋势,男女性的体型有显著性差异。将鄂温左族的体型值与国国内外资料进行了比较。     

江西赣州城市成年客家人体型及其年龄变化

采用Heath-Carter人体测量法对江西城市客家人304例(男154例,女150例)进行了体型评定。结果显示:1)江西城市客家人男性平均体型值为4.0-4.6-2.0,属于偏内胚层的中胚层体型;女性平均体型值为5.0-4.2-1.9,属于偏中胚层的内胚层体型。2)男女均以30岁为体型分界点,表现为30岁前后的体型差异。3)60岁前男女体型存在显著性差异。60岁后男女体型没有差异。4)与国内其他城市汉族比较,城市客家人男性平均体型点与内蒙古汉族最近,女性与云南汉族最为接近。客家人男女体型较其他城市汉族纤瘦,身体的线性度较高。     

布依族成人Heath-Carter法体型研究

本文运用Heath-Carter人体测量体型方法,研究了贵州省布依族494例(男259例,女235例)成人体型。研究结果表明:(1)布依族男性与女性平均体型均为偏内胚层的中胚层体型,男性均数为3·0—5·3—2·4,女性均数为4·3—4·9—1·9。(2)随年龄增长,布依族男性内因子值变化不大,中因子值增大,外因子值减小。但总的说来,男性体型各年龄组变化不大。(3)随年龄增长,女性内因子值与中因子值增大,外因子值减小。(4)布依族体型介于南方人群和北方人群之间。     

黑衣壮族成人Heath-Carter法体型研究

为探讨我国黑衣壮族成人的体型特征,本文采用Heath Carter人体测量法对广西壮族自治区百色市那坡县城厢乡331例(男165,女166)20—60岁的黑衣壮族成人进行了体型评定。结果表明:(1)黑衣壮族成人男女的平均体型值分别为1 58-5 19-2 69和2 99-4 43-1 79,黑衣壮族成人男女分别属偏外胚层的中胚层体型和偏内胚层的中胚层体型;(2)黑衣壮族成人男女间SAD值为1 85,T为16 04,男女间的体型有显著性差异(P<0 001);(3)与国内八个少数民族群体相比,黑衣壮族男性内因子值最小,中因子值最高,男、女性其它因子值居中。     

内蒙古汉族青少年体型分析

运用Heath-Carter体型法,对内蒙古地区3088名（男1489,女1599）7－18岁汉族城乡青少年体型进行分析。结果表明城乡男生偏中胚层型的外胚层型体型最多,中胚层－外胚层均衡型和偏外胚层型的中胚层型 之;城乡女生偏中胚层型的内胚层型体型最多,三胚层中间型和偏内胚层型换上胚层型次之。8－13岁时,同性别同龄组城乡学生的体型差异明显,13岁以后体型接近,城乡男女学生体型的性别间差别显著。     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.