灯盏花中的糖苷

从灯盏花(Erigeron breviscapus (Vant.) Hand.-Mazz.)全株的乙醇提取物的正丁醇部分分得10个化合物,通过波谱方法鉴定为erigeside Ⅰ (1)、γ-吡喃酮-3-O-β-D-[6′-(4″-羟基-3″,5″-二甲氧基苯甲酰)-]-吡喃葡萄糖苷(eriges ide D, 2)、erigeside A (3)、erigeside B (4)、erigesi de Ⅱ (5)、 7-O-β-D-吡喃葡萄糖-6-甲氧基香豆素(6)、 icariside B2 (7)、 blumenol C 葡萄糖苷(8)、 (+) -丁香树酯醇 O-β-D-吡喃葡萄糖苷(9)和野黄芩苷甲酯(10).用X射线单晶衍射方法确定了化合物7的绝对构型.2是一个新化合物,7、8和9首次从该属植物分离得到,6首次从该种植物分离得到.     

兖州卷柏化学成分及体外抗菌活性研究

本文研究兖州卷柏Selaginella involvens Spring.的化学成分及体外抗菌活性.运用反复色谱层析进行纯化分离得到7个化合物,经波谱解析结合理化鉴定确定化合物结构为:正十六烷酸(1),正十八烷酸(2),β-谷甾醇(3),豆甾醇(4),穗花杉双黄酮(5),β-D-glucopyranoside,(3β)-cholest-5-en-3yl(6),β-香树脂醇(7).化合物1～7均首次从该植物中分离得到,6和7首次从该属植物中分离得到.此外研究了化合物5、6和7的体外抗菌活性.化合物5、6和7可能为兖州卷柏抗肺炎病菌的主要物质基础.     

扁桃叶的化学成分研究

从芒果属植物扁桃(Mangifera persiciformis C.Y.Wu et T.L.Ming)叶乙醇提取物乙酸乙酯萃取部位中分离得到7个化合物,经波谱鉴定为没食子酸甲酯(1),没食子酸(2),3,4-二羟基苯甲酸(3),槲皮素(4),山奈酚-3-O-β-D-葡萄糖苷(5),槲皮素-3-O-β-D-葡萄糖苷(6)和芒果苷(7).其中化合物1、3、5、6为首次从该植物中分离得到.     

团花树皮的化学成分研究

采用硅胶、MCI和Sephadex LH-20层析方法对团花树皮的化学成分进行分离纯化,运用现代波谱技术鉴定了10个化合物:4-carboxy-3-hydroxy-5-methylphenyl 3-methoxy-4-hydroxy-5-methylbenzoate(1),谷甾醇-3-O-(6’-O-棕榈酰基)-β-D-葡萄糖苷(2),喹诺酸-3-O-α-L-鼠李糖苷(3),clethric acid(4),常春藤苷元(5),钩藤苷元C(6),morolic acid(7),咖啡酸甲酯(8),卡丹宾(9)和3α-二氢卡丹宾(10)。其中化合物1为一个新的酚性成分,化合物2～8首次从该属植物中分离得到。     

小叶石楠中苷类化学成分的研究

从小叶石楠[Photinia parvifolia (Pritz.)Schneid]茎中分离得到10种化合物,利用波谱学方法分别鉴定为：（6′-O-palmitoly)-sitosterol-3-O-β-D-glucoside(1),isotachioside(2)、hexaacetate of (-)-lyoniresinol-3α-L-rhamnopyranoside(3a),koaburaside(4)、2,6-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside(5),3-O-(β-D-glucopyranosyl)-1-(3′,5′-dimethoxy-4′-hydroxyphenyl)-1-propanone(6),di-O-methylcrenatin(7),L-threoguaiacylglycerol 8-O-β-glucopyranoside(8),苦杏仁苷（9）,D-threo-guaiacylglycerol 8-O-β-glucopyranoside(10)。以上10个化合物均为首次从该属植物中分离得到。     

顶羽菊化学成分的研究

从顶羽菊(Centaurea repens L.)中分离得到10个化合物,经光谱分析、化学方法及与已知化合物对照,鉴定它们分别为：三十四碳酸(1)、豆甾—7—烯—3—醇(2)、β—谷甾醇(3)、5—羟基—6,7—二甲氧基黄酮(4)、5—羟基—6—甲基7—O—α—D—半乳吡喃糖双氧黄酮苷(5)、2,4—二(邻甲基偶氮苯)—萘酚—1(6)、β—谷甾醇—β—D—葡萄糖苷(7)、洋芹素—5—O—β—D—葡萄糖苷(8)、洋芹素(9)、山奈素—3—O—β—D—葡萄糖苷(10)。其中化合物(6)是首次从天然界获得的。     

草果果实中的酚性成分

从草果( Amomum tsao-ko) 果实的甲醇提取物中分离得到了9 个酚性化合物, 其中一个为新的糖基被酰化的酚性配糖体。用1D, 2D NMR 和MS 等现代波谱学方法鉴定为2-甲氧基-1 , 4-二苯酚-1-O - [6- O -(3-甲氧基-4-羟基苯甲酰基) ]-β-D-吡喃葡萄糖苷(1) 。8 个已知化合物分别为3′, 5′-二-C-β-D-吡喃葡萄糖基根皮素( 2)、芦丁(3) 、槲皮素-3- O-β-D-吡喃葡萄糖苷(4 ) 、邻苯三酚( 5 )、邻苯二酚( 6) 、对羟基苯甲酸( 7)、原儿茶酸(8) 和香草酸(9) 。化合物2 , 3 , 5 , 7～9 均为首次从草果果实中分离得到。     

广东土牛膝的化学成分(英文)

广东土牛膝为菊科泽兰属植物华泽兰(Eupatorium chinense)的干燥根。从其甲醇提取物中共分离得到11个化合物,其中eupatorinA(1)为一新化合物,经波谱学方法鉴定为(threo)-3-O-acetyl-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxy-1-(E)-propenyl)-2,6-dimethoxyphenoxy]propyl-β-D-glucopy-ranoside。已知化合物分别鉴定为(threo)-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxy-1-(E)-propenyl)-2,6-dimethoxyphenox-y]-propyl-β-D-glucopyranoside(2),ardisiacrispinA(3),ardisiac-rispinB(4),euparone(5),3-(2,3-dihydroxy-isopen-tyl)-4-hydroxyacetophenone(6),12,13-di-hydroxy-euparin(7),gymnastone(8),N-(2′-hydroxy-tetracosanosyl)-2-amino-1,3,4-trihydroxy-octa-dec-8-(E)-ene(9),stigmasterol(10)和stigmasterol-3-O-β-D-glucopyranoside(11)。化合物2-4为首次从菊科植物,5-8为首次从泽兰属植物中分离得到。     

斑叶紫金牛化学成分的研究（Ⅰ）

采用95%乙醇提取,反复硅胶柱层析分离和光谱、波谱方法鉴定结构,从斑叶紫金牛(Ardisia punctataLindl.)中初步分离鉴定出7个化合物,2-甲基-5-[14(顺)-十九烯基]-1,3-间苯二酚(1),2-甲基-5-壬烷基-1,3-间苯二酚(2),3-0-[6'-O-palmitoyl-β-D-glucosyl-]-spinasta-7,22(23)-diene(3a),3-O-[6'-O-pahnitoyl]-β-D-sin-cosyl-pyranosyl stignmsterol(3b),岩白菜素(4),11-O-(4'-O-methylgalloyl)-bergenin(5),正二十四烷酸(6).所有化合物均为首次从该植物中获得,其中化合物2和6为首次从该属植物中分得.     

爆杖花的黄酮类成分研究

爆杖花(Rhododendron spinuliferum)茎叶75%丙酮水提取物采用硅胶柱色谱、Sephadex LH-20色谱、高效液相色谱等技术分离纯化,从其乙酸乙酯部分中共分离和鉴定了6个黄酮类化合物,槲皮素-3-O-[3″,4″-O-(异丙叉基)-β-D-木吡喃糖苷] (1),二氢槲皮素(2),二氢槲皮素-3-O-β-D-木吡喃糖苷(3),5,7,4′-三羟基-二氢黄酮醇-3-O-α-L-鼠李吡喃糖苷(4),二氢槲皮素-3-O-α-L-鼠李吡喃糖苷(5),花青素A-2(6).其中化合物1为新化合物,爆杖花的化学成分为首次报道.     

Studies on the Constituents of Wikstroemia Chamaedaphne

Wikstroemia chamaedaphne is a traditional chinese medicinal herb, its flavonoid compounds of leaf, which possess beneficial effect on the treatment of hepatitis; have been isolated. By means of mixed solvents and polyamide column chromatography, four crystallinic compounds were obtained, they were 5, 7-dihydroxy-3″-methoxy flavone-4-O-mono-D-glucoside; 5, 7, 4″-trihydroxy, flavone-3-O-β-mono-D-glucoside; 5, 7, 3′, 4′-tetrahydroxy flavone-3-O-β-mono-D-glucoside; 5, 7, 3″, 4′-tetrahydroxy flavone-8-C-β-mono-D-glucoside. From ether soluble fraetion, n-hentriacontane, triacontanol, octacosanol, and 29-hydroxy-ncnacosan-3-one were obtained. These constituents were identified by spectroscopic analysis (UV, IR, NMR, MS), preparation of derivatives, hydrolysis of acid and enzyme, and determination of physico-chemical constants, respectively.     

Xanthones from Tovomita pyrifolium

The wood of Tovomita pyrifolium (Guttiferae) contains the novel tovopyrifolins A [1,6-dihydroxy-7-methoxy-5-prenyl-6′,6′-dimethylpyrano (2′,3′:3,2)xanthone], B (1,5-dihydroxy-3,4-dimethoxyxanthone) and C (1,3,5-trihydroxy-2-methoxyxanthone) and also the known tovophyllins A and B [structure revised to 1,6-dihydroxy-5-prenyl-6′, 6′-dimethylpyrano(2′,3′:3,2)-6″,6″-dimethylpyrano(2″,3″:7,8)xanthone].     

Flavonol glycosides in leaves of Spinacia oleracea

Besides spinatoside (3,6-dimethoxy-5,7,3′,4′-tetrahydroxyflavone 4′-O-β-D-glucopyranuronide), three new flavonol glycosides have now been isolated from the polar fractions of the methanolic extract of Spinacia oleracea. They have been identified as patuletin 3-O-β-D-glucopyranosyl-(1 → 6)-[β-D-apiofuranosyl-(1 → 2)]-β-D-glucopyranoside, patuletin 3-O-β-gentiobioside and spinacetin 3-O-β-gentiobioside, respectively.     

Diarylpropanoids from Iryanthera polyneura

The trunk wood of Iryanthera polyneura Ducke (Myristicaceae) contains pinocembrin, 1-(2′,4′-dihydroxyphenyl)-3-(3″,4″-methylenedioxyphenyl)-propane, 1-(2′,4′-dihydroxy-3′-methylphenyl)-3-(2″-methoxy-4″, 5″-methylenedioxyphenyl)-propane and 4,2′,4′-trihydroxy-3-methoxydihydrochalcone.     

鬼针草中一个新的查耳酮甙

从鬼针草BidenspilosaL .地上部分的丙酮提取物中 ,分离鉴定了 1 8个化合物 ,其中包括一个新的查耳酮甙类化合物 (α,3,2′,4′ tetrahydroxy 2′ O β D glucopyranosylchalcone,2 )。其它化合物分别鉴定为butein (1 ) ,okanin 4 methylether 3′ O β glucoside (3) ,sulfuretin (4) ,6 ,7,3′,4′ tetrahydroxyaurone (5) ,海生菊苷 (maritimein ,6) ,(Z ) 6 O (6″ acetyl β D glucopyr anosyl) 6 ,7,3′,4′ tetrahydroxy aurone (7) ,(Z ) 6 O (4″,6″ diacetyl β D glucopyranosyl) 6 ,7,3′,4′ tetrahydroxy aurone (8) ,(Z ) 6 O (3″,4″,6″ triacetyl β D glucopyranosyl) 6 ,7,3′,4′ tetrahydroxy aurone (9) ,木犀草素 (luteolin ,1 0 ) ,槲皮素 (quercetin,1 1 ) ,异槲皮苷 (iso quercitrin,1 2 ) ,芦丁 (rutin,1 3) ,黄芪苷 (astragalin,1 4 ) ,quercetin 3,4′ dimethylether 7 O rutinoside (1 5) ,反式丁烯二酸 (1 6) ,2 β D glucopyranosyloxy 1 hydroxy trideca 3 ,5,7,9,1 1 pentayne (1 7)和 3 β D glucopyranosyloxy 1 hydroxy 6 (E ) tetradecene 8,1 0 ,1 2 triyne (1 8)。     

Structural confirmation of dihydrocinnamic acids from Adiscanthus fusciflorus by 13C NMR

In the wood of Adiscanthus fusciflorus six known alkaloids 4-methoxy-2-quinolone, 1-methyl-4-methoxy-2-quinolone, dictamine, skimmianine, γ-fagarine and N-methylflindersine and two new dihydrocinnamic acids 3-[2′,6′-dimethoxy-6″,6″-dimethylpyrano(2″,3″:4′, 3′)phenyl]-propionic acid and its methyl ester were identified. The structures of the dihydrocinnamic acid derivatives were confirmed by ¹³C NMR.     

Four isoflavanones from the stem bark of Platycelphium voënse

From the stem bark of Platycelphium voënse (Leguminosae) four new isoflavanones were isolated and characterized as (S)-5,7-dihydroxy-2′,4′-dimethoxy-3′-(3″-methylbut-2″-enyl)-isoflavanone (trivial name platyisoflavanone A), (±)-5,7,2′-trihydroxy-4′-methoxy-3′-(3″-methylbut-2″-enyl)-isoflavanone (platyisoflavanone B), 5,7-dihydroxy-4′-methoxy-2″-(2?-hydroxyisopropyl)-dihydrofurano-[4″,5″:3′,2′]-isoflavanone (platyisoflavanone C) and 5,7,2′,3″-tetrahydroxy-2″,2″-dimethyldihydropyrano-[5″,6″:3′,4′]-isoflavanone (platyisoflavanone D). In addition, the known isoflavanones, sophoraisoflavanone A and glyasperin F; the isoflavone, formononetin; two flavones, kumatakenin and isokaempferide; as well as two triterpenes, betulin and β-amyrin were identified. The structures were elucidated on the basis of spectroscopic evidence. Platyisoflavanone A showed antibacterial activity against Mycobacterium tuberculosis in the microplate alamar blue assay (MABA) with MIC = 23.7 μM, but also showed cytotoxicity (IC₅₀ = 21.1 μM) in the vero cell test.     

Phenolic compounds from Selaginella moellendorfii

Chemical investigation of the leaves and roots of Selaginella moellendorfii Hieron has resulted in the isolation and characterization of two new flavone glucosides, 7‐O‐(β‐glucopyranosyl(1→2)‐[β‐glucopyranosyl(1→6)]‐β‐glucopyranosyl)flavone‐3′,4′,5,7‐tetraol ( 1 ) and 7‐O‐(β‐glucopyranosyl(1→2)‐[β‐glucopyranosyl(1→6)]‐β‐glucopyranosyl)flavone‐4′,5,7‐triol ( 2 ), two new biflavonoids, 2,3‐dihydroflavone‐5,7,4′‐triol‐(3′→8″)‐flavone‐5″,6″,7″,4′′′‐tetraol ( 3 ) and 6‐methylflavone‐5,7,4′‐triol‐(3′→O→4′′′)‐6″‐methylflavone‐5″,7″‐diol ( 4 ), two new lignans, (7′E)‐3,5,3′,5′‐tetramethoxy‐8 : 4′‐oxyneolign‐7′‐ene‐4,9,9′‐triol ( 5 ) and 3,3′‐dimethoxylign‐8′‐ene‐4,4′,9‐triol ( 6 ), together with two known monolignans, four known lignans, and four known biflavonoids. Their structures were established by spectroscopic means and by comparison with literature values.     

慈溪麦冬甙A和B的结构

从浙江慈溪产中药麦冬（Ｏｐｈｉｏｐｏｇｏｎ ｊａｐｏｎｉｃｕｍ）中分离得到２个新的Ｃ２７甾体甙－－慈溪麦冬甙Ａ（２）和Ｂ（３）以及已知甙ｏｐｈｉｏｇｅｎｉｎ３－氧－α－Ｌ－鼠李糖吡喃基（１→２）「β－Ｄ－木糖吡喃基（１→３）」－β－Ｄ－葡萄糖吡喃甙（２）和ｏｐｈｉｏｇｅｎｉｎ ３－氧－α－Ｌ－鼠李糖吡喃基（１→２）「β－Ｄ－木糖吡喃基（１→３）」「β－Ｄ－葡萄糖吡喃基（１→４）」－β－Ｄ－葡萄糖吡     

Molecular Cloning and Construction of agp Gene Deletion-mutant in Cyanobacterium Synechocystis sp. PCC 6803

Nine compounds were isolated from Elsholtzia blanda (Benth.) Benth. Their　structures were identified with spectral and chemical methods as follows: 5,6-dihydro-6-styry-2-pyrone (1), friedelin (2), 4-hydroxy-3-methoxystyrene (3), 5,2′-dimethoxy-6,7-methylene dioxyflavanone (4), 5-hydroxy-7-methoxy-6-O-［α- L -rhamnopyranosyl(1→2)-β- D -fucopyranosyl］ flavone glycoside (5), 5,5′-dihydroxy-7-acetoxyl-6,8,3″,3″-tetramethylpyran　(3′,4′)　flavone (6), 5,5′-dihydroxy-7-(α-methyl) butyroxyl-6,8,3″,3″-tetramethylpyran (3′,4′) flavone (7), 5,5′-dihydroxy-6,7-methylenedioxy-8,3″,3″-trimethylpyran　(3′,4′)　flavone (8), glucosyringic acid (9). Among them, 6, 7 and 8 are new compounds, named as sifanghaoine Ⅰ,Ⅱ and Ⅲ, respectively.