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91.
该文利用23个微卫星标记对103尾大黄鱼繁育亲本进行遗传多样性检测和亲缘关系重建分析,并构建繁育体系指导大黄鱼配组。遗传多样性检测显示,103尾亲鱼在23个座位共获得等位基因数134个,平均5.82个,总平均观察杂合度0.599 3,表明该繁育群体尚保持一定水平的遗传多样性。采用似然率和组合优化法统计模型重建的同胞关系不尽相同,但结果均证实了这些繁育亲本亲缘关系十分相近。配组比对分析结果显示,两种方法的配组方案一致性高达85%,最终选择组合优化法的分组方案指导大黄鱼配组繁育。 相似文献
92.
G. La Rosa R. Calero-Bernal J.E. Pérez-Martín D. Tonanzi F. Galati F.J. Serrano-Aguilera B.M. Rosenthal E. Pozio 《International journal for parasitology》2018,48(7):543-553
Recurrent self-mating can result in nearly clonal propagation of biological lineages, but even occasional outcrossing can serve to redistribute variation in future generations, providing cohesion among regional populations. The zoonotic parasite Trichinella spiralis has been suspected to undergo frequent inbreeding, resulting in genetically uniform larval cohorts which differ markedly from one another. Here, we explored the extent of inbreeding for this parasite by determining how genetic variation (at variable microsatellite markers) is distributed among 1379 larvae derived from 41 wild boars in Extremadura, Spain. In particular, we sought to determine how much of the genetic variation in this region’s parasites occurs among the larvae of any given wild boar, and whether each derives from one, or more, parental lineages. We found strong evidence for inbreeding, resulting in genetically distinct parasite subpopulations among the parasites derived from many pairs of wild boar. Fully two-thirds of these parasite cohorts appear to derive from inbred parents; in 10% of the wild boars, parasites were so inbred as to become absolutely fixed in all of the assayed genetic loci. In spite of this, more than one pair of parents appear to have given rise to the infections in one-third of the sampled wild boars, resulting in mixed infections. These mixed infections should slow losses of heterozygosity and multi-locus polymorphism in any given parasite lineage. Such outcrossing should limit distinctions that would otherwise accumulate among transmission chains, thereby enforcing cohesion through the region’s population in spite of its marked departure from panmixia. Conditions of transmission may differ in other regions, where such epidemiological features may engender different evolutionary outcomes. 相似文献
93.
94.
A two-locus haploid model of sexual selection is investigated to explore evolution of disassortative and assortative mating preferences based on imprinting. In this model, individuals imprint on a genetically transmitted trait during early ontogeny and choosy females later use those parental images as a criterion of mate choice. It is assumed that the presence or absence of the female preference is determined by a genetic locus. In order to incorporate such mechanisms as inbreeding depression and heterozygous advantage into our haploid framework, we assume that same-type matings are less fertile than different-type mating. The model suggests that: if all the females have a disassortative mating preference a viability-reducing trait may be maintained even without the fertility cost of same-type matings; a disassortative mating preference can be established even if it is initially rare, when there is a fertility cost of same-type matings. Further, an assortative mating preference is less likely to evolve than a disassortative mating preference. The model may be applicable to the evolution of MHC-disassortative mating preferences documented in house mice and humans. 相似文献
95.
Inbreeding depression and its consequences for mate choice have been extensively studied in free-living animals. However, very little is known about its significance for parasites, although it is well recognized that the mating systems of parasites can have important implications for their epidemiology and evolution. In this article, we show that the cestode Schistocephalus solidus shows incestuous mate preference despite evidence for very strong inbreeding depression. When given the simultaneous choice between mating with a sibling and an unrelated partner, on average, the cestode preferred its sibling. To explain this surprising result, we present three hypotheses that suggest different benefits to fitness of incestuous mating, which could, alone or in concert, outweigh the cost of inbreeding depression. 相似文献
96.
Ogilvie MB 《Journal of the history of biology》2007,40(3):467-507
Helen Dean King’s scientific work focused on inbreeding using experimental data collected from standardized laboratory rats
to elucidate problems in human heredity. The meticulous care with which she carried on her inbreeding experiments assured
that her results were dependable and her theoretical explanations credible. By using her nearly homozygous rats as desired
commodities, she also was granted access to venues and people otherwise unavailable to her as a woman. King’s scientific career
was made possible through her life experiences. She earned a doctorate from Bryn Mawr College under Thomas Hunt Morgan and
spent a productive career at the Wistar Institute of Anatomy and Biology in Philadelphia where she had access to the experimental
subjects which made her career possible. In this paper I examine King’s work on inbreeding, her participation in the debates
over eugenics, her position at the Wistar Institute, her status as a woman working with mostly male scientists, and her involvement
with popular science. 相似文献
97.
A. Biere 《Journal of evolutionary biology》1991,4(3):467-486
Selection on the timing of seedling emergence was investigated in an experimental population of Lychnis flos-cuculi, a perennial hay-meadow species. Seeds obtained from a full diallel cross of 8 genotypes from a field population were sown along an environment gradient that included the parental site. Significant directional selection for early emergence was found and the intensity of selection varied among sites. Emergence time varied significantly among progeny families of different maternal and paternal genotypes. These differences could be attributed to parental effects whereas narrow-sense heritabilities were close to zero. Survivorship until autumn differed among progeny of paternal families. Survivorship of maternal progeny varied among sites. Whereas differences in survival and plant size among individuals from different emergence cohorts persisted over the winter, the significance of these differences among progeny from different parental genotypes disappeared. It is suggested that a response to selection on emergence time might be low since (1) the narrow sense heritability was low, (2) parental genotypes differed in their effect on offspring emergence time when used as female parent or as pollen donor and (3) there was a family x site interaction for survival. Families with relatively early emerging seedlings also had a significantly higher seed weight, emergence percentage, and plant weight although the strength of these among-family correlations varied among sites. It is therefore not likely that simultaneous selection on emergence time and either of these traits would retard a response to selection on emergence time. 相似文献
98.
Wayne Boucher 《Journal of mathematical biology》1988,26(1):57-64
Wright's rule for calculating the inbreeding coefficient for an arbitrary pedigree is proven for both autosomal and X-linked loci.Supported by NSF Grant PHY-84-16691 相似文献
99.
L. D. Van Vleck 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》1993,85(5):545-549
Summary Formulas are presented to illustrate the calculation of correct variances of prediction error (PEV) and the correlation between true and predicted values (rTI) when the incorrect variance-covariance matrix for the random effects is used in mixed-model equations (MME). The example with progeny records of highly related and inbred sires showed that PEV were underestimated from the diagonals of the inverse of the coefficient matrix of the MME when sires were assumed unrelated and not inbred and were overestimated when relationships among sires were calculated with Henderson's simple rules for the inverse of the numerator relationship matrix, A-1, which do not consider inbreeding. When Quaas' rules for A-1, which do consider inbreeding, are used, the correct PEV are obtained. In the example, calculations of rTI from the diagonals of the inverse of the coefficient matrix were too large when relationships and inbreeding were ignored and were obviously wrong when the approximation to the numerator relationship matrix, A, was based on the simple rules for calculating A-1. If the correct A is used in the MME, the calculation of rTI may be incorrect if inbreeding of the evaluated individual is not considered. If inbreeding is known, adjustment for inbreeding is easy for calculation of rTI.Published as paper no. 9947, Journal Ser, Nebraska Agric Res Div, University of Nebraska, Lincoln, Neb. 相似文献
100.
R. Frankham G. J. Smith D. A. Briscoe 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》1993,86(8):1023-1027
The effects of inbreeding, with (IS) and without selection (IO) for reproductive fitness, on inbreeding depression and heterozygosity were evaluated in 20 lines of each treatment inbred over seven generations using full-sib mating. The survival of lines was significantly greater in IS (20/20) than in IO (15/20). The competitive index measure of reproductive fitness was significantly lower in the inbred lines than in the outbred base population, but not significantly different in surviving IS and IO lines. There was a trend for higher fitness in the IS treatment as relative fitnesses were 19% higher in IS than IO for surviving lines and 59% higher for all lines. Heterozygosities were lower in the inbred lines than in the base population, and significantly higher in the IS than the IO lines. Consequently, the reduction of inbreeding depression in IS has been achieved, at least in part, by slowing the rate of fixation. 相似文献