正畸治疗上颌尖牙埋伏阻生38例的临床分析

目的:探讨正畸导萌治疗上颌尖牙埋伏阻生的临床效果。方法:对38例上颌尖牙埋伏阻生患者的临床资料进行回顾性分析,总结正畸导萌治疗上颌尖牙埋伏阻生的临床效果。结果:经过17-25个月(平均20个月)的正畸治疗,38例上颌埋伏阻生尖牙均完全萌出纳入到正常牙列中,牙齿及牙周组织未见异常,牙齿排列整齐且咬合关系良好,临床效果令人满意。结论:正畸配合外科手术导萌可有效避免上颌尖牙因埋伏阻生而拔除给患者带来的美观和功能上的缺憾,是一种有效治疗上颌尖牙埋伏阻生的方法。     

埋伏倒置阻生上颌中切牙不同正畸牵引方式的比较

目的:比较前方牵引器及下颌支抗颌间牵引两种正畸牵引方式矫治上中切牙埋伏倒置阻生的疗效。方法:选择10例患者10颗埋伏倒置阻生上颌中切牙,在三维CT片上的位置、三维方向和埋伏阻生的程度均相似,随机分为两组,分别行前方牵引器牵引和颌间牵引,对两组的牵引时间和成功率进行比较,分别采用t检验和x2检验进行统计学处理。结果:前方牵引组牵引时间长于颌间牵引组,有显著差异(P0.05),前方牵引组成功率为100%,颌间牵引组为60%,差异有显著性(P0.01)。结论:埋伏倒置阻生的上中切牙外科开窗术后,通过前方牵引器牵引的时间显著长于下颌支抗颌间牵引,但成功率显著高于颌间牵引。     

埋伏倒置阻生上颌中切牙不同正畸牵引方式的比较

目的：比较前方牵引器及下颌支抗颌间牵引两种正畸牵引方式矫治上中切牙埋伏倒置阻生的疗效。方法：选择10例患者10颗埋伏倒置阻生上领中切牙,在三维CT片上的位置、三维方向和埋伏阻生的程度均相似,随机分为两组,分别行前方牵引器牵引和颌间牵引,对两组的牵引时间和成功率进行比较,分别采用t检验和x2检验进行统计学处理。结果：前方牵引组牵引时间长于颌间牵引组,有显著差异（P〈0．05）,前方牵引组成功率为100％,颌间牵引组为60％,差异有显著性（P〈0．01）。结论：埋伏倒置阻生的上中切牙外科开窗术后,通过前方牵引器牵引的时间显著长于下颌支抗颌间牵引,但成功率显著高于颌间牵引。     

微切口超声乳化联合小梁切除术治疗白内障合并青光眼的疗效观察

目的:探讨微切口超声乳化联合小梁切除术治疗白内障合并青光眼的临床疗效。方法:选取2013年1月到2014年1月我院收治的白内障合并青光眼患者100例,按照随机数字表法将患者分为研究组和对照组,每组50例,对照组给予常规超声乳化联合小梁切除术进行治疗,研究组给予微切口超声乳化联合小梁切除术治疗,比较两组术前、术后裸眼视力、散光、眼压,并比较两组术后并发症。结果:两组术后裸眼视力、散光和眼压均较术前明显好转,与术前比较差异具有统计学意义(P0.05),且研究组术后裸眼视力、散光和眼压均优于对照组,两组比较差异具有统计学意义(P0.05);研究组术后并发症发生率显著低于对照组,两组比较差异具有统计学意义(P0.05)。结论:微切口超声乳化联合小梁切除术治疗白内障合并青光眼疗效确切,且术后并发症较少。     

厚度微创椎板间开窗椎管扩大术治疗腰椎管狭窄的疗效

目的:探讨微创椎板间开窗椎管扩大术治疗腰椎管狭窄(LSS)的疗效。方法:对收治的40例LSS患者(研究组)前瞻性实施微创椎板间开窗椎管扩大术治疗,回顾性分析实施常规后路椎板切除减压术治疗的40例LSS患者(对照组)的临床资料,术后随访6~24个月,对比两组患者治疗效果。结果:两组手术时间比较差异无统计学意义(P0.05),但研究组住院时间短于对照组,术中失血量少于对照组(P0.05);两组术后JOA评分有效率、轴性症状发生率、椎间隙高度、腰椎曲度、滑脱程度比较差异无统计学意义(P0.05),但研究组术后伤椎疼痛VAS评分显著低于对照组(P0.05);对照组并发症总发生率高于研究组(P0.05)。结论:微创椎板间开窗椎管扩大术治疗LSS,与常规术式疗效相当,但手术创伤小,术后并发症少。     

下鼻道开窗术治疗慢性上颌窦炎32 例

目的:探讨下鼻道开窗术替代传统的上颌窦根治术治疗慢性上颌窦炎的手术方法及治疗效果。方法:通过对慢性上颌窦炎患者32例进行下鼻道开窗术治疗,并与同期进行上颌窦根治术31例比较。结果:下鼻道开窗术组一次手术痊愈率93.7%,上颌窦根治术组一次手术痊愈率93.5%,两组手术效果统计学处理无显著性差异,(u=1.24,u>0.05)。结论:下鼻道开窗术替代传统的上颌窦根治术,疗效相同,而且具有无面部肿胀麻木及牙齿酸胀等并发症。能够达到上颌窦根治的目的并具有微创的特点。     

下鼻道开窗术治疗慢性上颌窦炎32例

目的：探讨下鼻道开窗术替代传统的上颌窦根治术治疗慢性上颌窦炎的手术方法及治疗效果.方法：通过对慢性上颌窦炎患者32例进行下鼻道开窗术治疗,并与同期进行上颌窦根治术31例比较.结果：下鼻道开窗术组一次手术痊愈率93.7%,上颌窦根治术组一次手术痊愈率93.5%,两组手术效果统计学处理无显著性差异,（u=1.24,u〉0.05）.结论：下鼻道开窗术替代传统的上颌窦根治术,疗效相同,而且具有无面部肿胀麻木及牙齿酸胀等并发症.能够达到上颌窦根治的目的并具有微创的特点.     

真菌球型上颌窦炎鼻内镜下两种手术路径的临床研究

目的:比较鼻内镜下中鼻道联合下鼻道小视窗双路径术和单独下中鼻道开窗术治疗真菌球型上颌窦炎的临床疗效。方法:采用前瞻性随机对照试验,将2013年8月~2015年5月在我院择期行手术治疗的50例真菌球型上颌窦炎患者分为观察组与对照组,每组25例,对照组行鼻内镜单独下中鼻道开窗术,观察组在对照组的基础上联合下鼻道小视窗术。术前及术后6个月采用鼻腔鼻窦结局测试20条量表(SNOT-20)对两组患者进行评分,术后6个月对鼻黏膜纤毛清除功能及疗效进行评估,比较两组手术时间及术中出血量。结果:术后6个月两组SNOT-20量表评分显著低于术前,且观察组显著低于对照组(P0.05)。术后6个月观察组粘膜纤毛传输时间(MTT)显著低于对照组(P0.05)。两组总有效率、手术时间及术中出血量比较,差异均无统计学意义(P0.05)。结论:鼻内镜下以上两种手术路径治疗真菌球型上颌窦炎的疗效相近,但鼻内镜下中鼻道联合下鼻道小视窗双路径术更有利于减轻患者症状及促进鼻黏膜纤毛清除功能恢复。     

正畸患者埋伏牙患病情况的流行病学研究

目的:调查分析正畸患者埋伏牙的基本患病情况。方法:第四军医大学口腔正畸科2008.1.1-2011.4.23就诊的6876例患者中,以确诊的589例埋伏牙患者为研究对象,对其性别,年龄,部位和数量等基本情况进行流行病学研究。结果:埋伏牙在第四军医大学口腔正畸患者中患病率为8.56%,以上颌好发,上颌尖牙患病率最高,其次为埋伏多生牙;以单发为主;女性较男性多发。结论:埋伏牙在正畸门诊患者中患病率较高,尤其是上颌尖牙,提示正畸医生在患者就诊时要注意埋伏牙的早发现及早治疗。     

3D数字辅助超声骨刀技术在胸椎管黄韧带骨化症中的短期疗效评价

摘要 目的：探讨使用3D数字技术结合超声骨刀技术在胸椎管黄韧带骨化症中的临床疗效和安全性。方法：回顾性分析我院诊断为胸椎管骨化症,在2016.01至2019.01行手术治疗的共计38例患者。根据手术方法的不同,将其分为3D+超声骨刀组（观察组,17例）与磨钻治疗组（对照组,21例）。比较两组患者的如下三大项指标：手术指标（术中出血、椎板切除时间等）,疗效指标（术后JOA评分等）及并发症指标（脑脊液漏等）。结果：两组患者在性别、年龄、椎体节段等指标中无统计学差异(P>0.05)。3D+超声骨刀组患者在出血量,椎板切除时间等指标中,显著优于对照组,存在统计学差异(P<0.05)。两组患者在术后JOA评分较手术前均有显著改善(P<0.05),且3D+超声骨刀组显著优于对照组。3D+超声骨刀组中出现4例脑脊液漏患者,而对照组中出现8例脑脊液漏患者。两组患者间无显著性差异 (P>0.05)。其中,3D+超声骨刀组中未出现器械损伤硬膜者,对照组中有2例出现器械损伤硬膜。结论：与传统的磨钻技术相比,使用3D打印技术+超声骨刀技术能够在提高临床疗效的同时,缩短手术时间与术中出血,并且具备较好的安全性。     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Entwicklungsgeschichte und Ultrastruktur von Pollenkitt und Exine bei nahe verwandten entomophilen und anemophilen Angiospermensippen derAlismataceae,Liliaceae, Juncaceae,Cyperaceae, Poaceae undAraceae

Some closely related members of the monocotyledonous familiesAlismataceae, Liliaceae, Juncaceae, Cyperaceae, Poaceae andAraceae with variable modes of pollination (insect- and wind-pollination) were studied in relation to the ultrastructure of pollenkitt and exine (amount, consistency and distribution of pollenkitt on the surface of pollen grains). The character syndromes of pollen cementing in entomophilous, anemophilous and intermediate (ambophilous or amphiphilous) monocotyledons are the same in principal as in dicotyledons. Comparing present with former results one can summarize: 1) The pollenkitt is always produced in the same manner by the anther tapetum in all angiosperm sub-classes. 2) The variable stickiness of entomophilous and anemophilous pollen always depends on the particular distribution and consistency of the pollenkitt, but not its amount on the pollen surface. 3) The mostly dry and powdery pollen of anemophilous plants always contains a variable amount of inactive pollenkitt in its exine cavities. 4) A step-by step change of the pollen cementing syndrome can be observed from entomophily towards anemophily. 5) From the omnipresence of pollenkitt in all wind-pollinated angiosperms studied one can conclude that the ancestors of anemophilous angiosperms probably have been zoophilous (i.e. entomophilous) throughout.

     

Identification and Characterization of the First Equine Parainfluenza Virus 5

正Dear Editor,Parainfluenza virus 5 (PIV5), known as canine parainfluenza virus in the veterinary field, is a negative-sense,nonsegmented, single-stranded RNA virus belonging to the Paramyxoviridae family (Chen 2018). The virus was first reported in primary monkey kidney cells in 1954 (Hsiung1972), then it has been frequently discovered in various     

Pathogenic Characterization and Full Length Genome Sequence of a Reassortant Infectious Bursal Disease Virus Newly Isolated in Pakistan

<正>Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segments of double-stranded RNA (segments A and B), targets B lymphocytes of bursa of Fabricious leading to immunosuppression. In Pakistan,poultry farming is the second biggest industry and IBD is the second biggest disease threating the poultry sector.However, there is limited genome information of IBDV