微生物学实验多样化教学之初探

实验教学是微生物教学的重要组成部分,是培养学生动手能力、分析和解决问题等能力的重要教学环节.通过适当修改实验方案、整体设计实验、解决实际问题和开设综合性实验等途径实现多样化的教学模式,实践表明可以显著提高学生的学习兴趣,充分调动学生的积极性、主动性和创造性.     

微生物双语教学中的实施策略与实践—交互教学提升课堂活力

探讨了微生物双语教学中采用交互式教学以发挥学生主体地位以及教师鼓励作用的教学策略.为了“有助于达到人才培养目标”又保证培养质量,精选了英文原版教材和国内选编教材;基于双语教学资源平台,了解学情,灵活把握双语教学的中英文比例;通过微生物理论与实践相结合和英文演讲辩论等提升课堂活力;适度改革双语教学考核等方式提高微生物双语教学效果.     

密切联系实际，加强学生应用微生物技术能力的培养——高等农业院校植物生产类和资源环境类专业微生物学课程教学浅谈

《农业微生物学》既是高等农业院校植物生产类和资源环境类专业的专业基础课程,也是和应用微生物技术密切相关的课程。多年的教学实践表明,只有在教学中密切联系实际,强化学生应用微生物技术能力的培养,才能让学生既熟练掌握普通微生物学基础知识和基本技能,又能拓宽知识面,激发学生的学习兴趣。同时,根据人才培养方案、就业形势以及社会需求开设《实用微生物技术》和《食用菌生产》等选修课程,既满足学生对微生物实用技术学习的需要,也为生产企业培养了技术人员。     

临床微生物教学规范化、标准化研究

微生物形态特点各异,种类繁多复杂,而临床微生物教学不但担任着教学的责任,还身兼临床工作。为了培养具有扎实基础、较强实践能力的医学人才,在建立规范化和表转化的临床微生物教学,能够提高教学质量,能够提升学生综合分析问题和实践动手的能力,还能够使学生明确学习目的,从而促进临床微生物教学改革。     

微生物双语教学中的实施策略与实践

探讨了微生物双语教学中采用交互式教学以发挥学生主体地位以及教师鼓励作用的教学策略.为了“有助于达到人才培养目标”又保证培养质量,精选了英文原版教材和国内选编教材;基于双语教学资源平台,了解学情,灵活把握双语教学的中英文比例;通过微生物理论与实践相结合和英文演讲辩论等提升课堂活力;适度改革双语教学考核等方式提高微生物双语...     

改革微生物学实验教学 培养学生创新能力

对微生物学实验课程体系的教学内容、教学条件和手段、考核方法进行了改革和探索,创建适合于培养我校不同专业学生的微生物实验教学体系,从而提高学生动手能力,培养学生创新能力。     

传统教学法与PBL结合在医学微生物学教学中的应用

PBL教学方法是一种全新的自主性的教学模式.把PBL教学方法引入病原微生物教学中,与传统教学方法相结合,提高了学生的学习自主性和学习的效果,并且进一步培养了学生的学习能力.这一尝试取得了良好的效果.     

“微生物的利用”的教学构思

选修1“生物技术实践”模块均为实验内容．“微生物的利用”是其中的一个教学单元,本单元包含3个微生物实验。按照新课标对本模块的要求,实验涉及的基础知识主要通过学生自学来完成,教师的任务主要是指导学生进行实验设计、完成实验、收集整理数据、写出报告和讨论交流。实验课是发展学生科学探究能力的良好载体。在“微生物的利用”教学单元中,就如何培养学生实验技能,充分发展学生的科学探究能力谈谈自己的教学构思。     

慕课背景下“微生物工程”实验课开放式教学模式探索

慕课等线上学习平台是教育信息化的结果,结合慕课对传统教学进行突破是近年来教学改革的热点之一。"微生物工程"课程是高等院校生物技术、生物工程专业的必修课,该课程具有很强的应用性和实践性。为了加深学生对理论知识的理解、培养学生的科研思维,我们在微生物工程实验课的教学中引入了一种基于慕课教学资源的开放式教学模式。结果表明,这种慕课背景下的开放式教学在提升学生学习兴趣、锻炼学生创造性思维、增强学生科研素养、培养学生团队协作能力等方面都具有很好的效果。     

提高微生物学实验课教学效果的探索与尝试

针对传统实验教学法造成学生学习被动和积极性不高等问题,在微生物实验教学实践中我们以培养学生能力为重点,对实验教学内容、实验教学方式、实验教学管理以及考核方式等方面的改革进行了探索与尝试.教学实践证明从微生物学实验教学的正确定位出发,规范实验教学大纲,采用基本技能训练模块、综合实验模块和创新实验模块相结合的教学方式和实验室开放教学管理模式是提高微生物实验教学效果的成功之举,对提高学生综合素质具有重要作用.     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Entwicklungsgeschichte und Ultrastruktur von Pollenkitt und Exine bei nahe verwandten entomophilen und anemophilen Angiospermensippen derAlismataceae,Liliaceae, Juncaceae,Cyperaceae, Poaceae undAraceae

Some closely related members of the monocotyledonous familiesAlismataceae, Liliaceae, Juncaceae, Cyperaceae, Poaceae andAraceae with variable modes of pollination (insect- and wind-pollination) were studied in relation to the ultrastructure of pollenkitt and exine (amount, consistency and distribution of pollenkitt on the surface of pollen grains). The character syndromes of pollen cementing in entomophilous, anemophilous and intermediate (ambophilous or amphiphilous) monocotyledons are the same in principal as in dicotyledons. Comparing present with former results one can summarize: 1) The pollenkitt is always produced in the same manner by the anther tapetum in all angiosperm sub-classes. 2) The variable stickiness of entomophilous and anemophilous pollen always depends on the particular distribution and consistency of the pollenkitt, but not its amount on the pollen surface. 3) The mostly dry and powdery pollen of anemophilous plants always contains a variable amount of inactive pollenkitt in its exine cavities. 4) A step-by step change of the pollen cementing syndrome can be observed from entomophily towards anemophily. 5) From the omnipresence of pollenkitt in all wind-pollinated angiosperms studied one can conclude that the ancestors of anemophilous angiosperms probably have been zoophilous (i.e. entomophilous) throughout.

     

Identification and Characterization of the First Equine Parainfluenza Virus 5

正Dear Editor,Parainfluenza virus 5 (PIV5), known as canine parainfluenza virus in the veterinary field, is a negative-sense,nonsegmented, single-stranded RNA virus belonging to the Paramyxoviridae family (Chen 2018). The virus was first reported in primary monkey kidney cells in 1954 (Hsiung1972), then it has been frequently discovered in various     

Pathogenic Characterization and Full Length Genome Sequence of a Reassortant Infectious Bursal Disease Virus Newly Isolated in Pakistan

<正>Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segments of double-stranded RNA (segments A and B), targets B lymphocytes of bursa of Fabricious leading to immunosuppression. In Pakistan,poultry farming is the second biggest industry and IBD is the second biggest disease threating the poultry sector.However, there is limited genome information of IBDV