医院岗位设置管理的做法与体会

目的 探讨医院实施岗位设置管理工作的做法,确保医院岗位设置管理工作顺利实施。方法 按照上级人事部门核准的事业单位岗位设置审核方案,结合自身实际,制定切实可行的医院岗位设置管理实施方案。结果 医院岗位设置管理工作顺利实施,效果显著。结论 要确保医院岗位设置管理工作顺利实施,领导重视是关键,全员参与是保障,公平公开是前提,按需设置是基础,激励约束是目的。     

对临床输血病案文书质量的调查与分析

目的 探讨临床输血病案文书的内涵质量。方法 采取随机抽查的方法对某院2009—2010年已经归档的输血病案,按卫生部“医院管理年和医疗质量万里行”活动内容进行调查。结果 发现多份病历不合格。结论 临床输血病案文书是临床医师对患者治疗过程的原始记录,是当时事态的真迹,是医疗事故或纠纷在认定是非、判明责任,以及医疗技术鉴定或司法鉴定时赖以立论的依据。因此,写好病案文书可减少医疗纠纷的发生。     

基于DEA的Malmquist指数的我国大型综合医院跨期效率研究

目的 评价大型综合医院效率。方法 采用DEA的CCR模型、BCC模型进行年度分析，再采用Malmquist指数进行跨期分析。结果 在所研究的22所大型综合医院中，2006—2007年有68.2%的医院处于规模报酬固定阶段；2006—2007年，63.6%的医院生产率变化主要是受到技术变化的影响，13.6%生产率变化是受到效率变化的影响，其他变化则是技术变化和效率变化共同作用。结论 研究期间，22所大型综合医院纯技术效率基本稳定，多数医院处于规模报酬固定阶段，生产率主要受技术变化的影响。     

中南大学湘雅系统医疗对口支援工作的创新

??????? 目的 探讨大学及附属医院如何在对口支援工作中发挥更好的作用的方法。方法 回顾性分析中南大学及附属医院在国家新医改背景下对医疗对口支援工作模式和机制的创新和效果。结果 该校通过模式和机制创新,医疗对口支援工作取得良好成效。结论 大学及附属医院利用学科建设和人才培养等优势,创新性地开展医疗对口支援工作,可取得更好成效。     

公立医院卫生资源配置和服务利用效率的分析及思考

?????? 目的 了解我国公立医院的卫生资源配置与利用效率情况。方法 运用数据包络分析法(DEA)对6家公立医院2010的投入与产出情况进行分析。结果 2家二级公立医院的效率评价排名优于4家三级医院。结论 加大对基层医疗单位的卫生资源投入力度,加强对三级公立医院卫生资源的整合重组,以提高公立医院的卫生资源配置与利用效率。     

患方对医院投诉管理的认知和诉求分析

目的 了解患方对医院投诉管理的认知和诉求状况,为制定医院投诉管理规范提供参考。方法 采用现场问卷调查的方法对4家医院的200名患者进行调查并对结果进行统计分析。结果 患方对医院投诉的知晓度有限;患方对完善投诉管理的重要性认同度较高;患方对系统规范化的投诉处理机制有强烈诉求;患方对医院投诉管理的现状并不满意。结论和建议 高度重视医疗投诉,加大对医疗投诉的宣传力度;完善投诉渠道,塑造缓和医患矛盾的内外部环境;建立投诉处理反馈机制,加强对投诉信息的有效利用。     

持续改进围术期预防性抗菌药物不合理使用成效分析

?????? 目的 分析围术期预防性抗菌药物使用中不合理使用的原因,并采取相应的干预对策。方法 2005年以来定期调查围术期抗菌药物预防使用状况,根据调查和反馈的结果不断改进干预措施。积极使用计算机网络和HIS的后台管理进行干预,同时将查出问题反馈给手术医生等一系列干预措施。结果 通过连年的综合干预,围术期抗菌药物带入手术室使用率从51.19%上升到97.33%,围术期预防性抗菌药物使用品种合格率从25.03%上升到79.68%,围术期预防性抗菌药物使用平均天数I类手术从5.49天下降到1.72天,II类手术从6.29下降到3.79天。结论 多部门联动、综合干预、持续改进是取得成效的关键。     

医护人员心理契约满足及其测量

??????? 目的 ? 探讨医护人员心理契约满足的内容结构,了解医护人员心理契约满足的维度,加强对医护人员心理契约管理。方法? 对294名临床科室医护人员进行心理契约问卷调查,并进行统计分析。结果? 医护人员心理契约满足为三维结构。发展责任,对总变异的贡献率为46.010%;规范责任,对总变异的贡献率为8.797%;人际责任,对总变异的贡献率为6.888%。表明该量表可靠性良好,也充分表明了心理契约量表的维度具有文化特性。结论?量表可靠性良好,充分表明了心理契约量表的维度具有文化特性,对医院人力资源管理具有指导性意义,有助于提升医院管理水平。     

公立医院理事会绩效评价指标体系的构建

目的 构建公立医院法人治理结构改革试点理事会绩效评价的指标体系。方法 首先通过文献研究和个人深入访谈法构建北京公立医院理事会绩效评价初步指标体系，然后通过德尔菲专家咨询法对指标体系进行优化。结果 专家打分结果显示，三级指标中，有4个指标的均值在重要性、可操作性和敏感性中只有一个维度小于7分，有3个指标的变异系数在重要性、可操作性和敏感性中只有一个维度大于0.3。结论 理事会绩效评价指标体系中理事会结构较理事会运作过程和结果的可操作性高，但重要性敏感性较低；有3个增加的三级指标分别是“战略与政策制定的效果评价”、“理事的培训效果评价”和“卫生行政部门对医院的绩效评价。     

北京大学所属医院洁净手术部质量管理监测结果分析

目的 通过对医院洁净手术部综合性能和管理现状监测结果的分析,发现质量管理中存在的问题,促进医院加强管理,保障洁净手术部有效运行。方法 回顾性分析洁净手术部检查资料,了解质量管理中存在的问题及薄弱环节,提出有效的改进措施。结果 洁净手术部的管理还存在着一定的缺陷,应进一步加强管理力度,定期监测。结论 洁净手术部的管理涉及多专业,多学科,多部门,是对医院感染管理工作的挑战。需要制定与此相适应的科学合理的运行和管理的措施,以保障洁净手术部的安全运行。     

利用集聚度评价卫生资源配置公平性的方法学探讨

卫生资源配置公平性评价是卫生系统研究的重要内容之一。文章将经济学领域中的集聚度概念引入卫生资源配置评价中,创新提出卫生资源配置集聚度（HRAD）的概念,在兼顾人口和地理因素的基础上,探索其在卫生资源配置公平性评价中的可行性,并利用2007—2012年我国医院床位规模数据进行实证研究,强调使用卫生资源集聚度方法的注意点。     

埃博拉诊疗中心病区突发事件应急处置预案及其应用

为提高我国援利医疗队医护人员对埃博拉诊疗中心（ETU）病区内突发事件的应急处置能力,对利比里亚多家已投入运行的ETU病房进行实地调研。围绕晕倒、锐器刺伤、意外跌倒、护理相关性损伤、病人逃离等发生频率较高的突发事件,研究建立了中国ETU病区突发事件应急处置预案。经过一段时间的运行,突发事件得到有效控制,处置过程未发生感染暴露事件。文章介绍的中国ETU病区突发事件应急处置预案与实践经验,可为国内外烈性传染病防治过程中病区突发事件的预防和处置提供参考借鉴。     

Chromosome-based gene co-expression analysis reveals regions associated with cancers: chromosome 1 as an example

Gene co-expression network analysis has been widely performed in systems biology. Here, I use a chromosome-based strategy to find potential chromosome regions associated with disease, and show an example of cancer. All results are available at http://bioinformatics.fafu.edu.cn/chrom-WGCNA/.

     

Apple gene function and gene family database: an integrated bioinformatics database for apple research

The apple (Malus domestica) is one of the most economically important fruit crops in the world, due its importance to human nutrition and health. To analyze the function and evolution of different apple genes, we developed apple gene function and gene family database (AppleGFDB) for collecting, storing, arranging, and integrating functional genomics information of the apple. The AppleGFDB provides several layers of information about the apple genes, including nucleotide and protein sequences, chromosomal locations, gene structures, and any publications related to these annotations. To further analyze the functional genomics data of apple genes, the AppleGFDB was designed to enable users to easily retrieve information through a suite of interfaces, including gene ontology, protein domain and InterPro. In addition, the database provides tools for analyzing the expression profiles and microRNAs of the apple. Moreover, all of the analyzed and collected data can be downloaded from the database. The database can also be accessed using a convenient web server that supports a full-text search, a BLAST sequence search, and database browsing. Furthermore, to facilitate cooperation among apple researchers, AppleGFDB is presented in a user-interactive platform, which provides users with the opportunity to modify apple gene annotations and submit publication information for related genes. AppleGFDB is available at http://www.applegene.org or http://gfdb.sdau.edu.cn/.     

Enhancing protein-vitamin binding residues prediction by multiple heterogeneous subspace SVMs ensemble

Background

Vitamins are typical ligands that play critical roles in various metabolic processes. The accurate identification of the vitamin-binding residues solely based on a protein sequence is of significant importance for the functional annotation of proteins, especially in the post-genomic era, when large volumes of protein sequences are accumulating quickly without being functionally annotated.

Results

In this paper, a new predictor called TargetVita is designed and implemented for predicting protein-vitamin binding residues using protein sequences. In TargetVita, features derived from the position-specific scoring matrix (PSSM), predicted protein secondary structure, and vitamin binding propensity are combined to form the original feature space; then, several feature subspaces are selected by performing different feature selection methods. Finally, based on the selected feature subspaces, heterogeneous SVMs are trained and then ensembled for performing prediction.

Conclusions

The experimental results obtained with four separate vitamin-binding benchmark datasets demonstrate that the proposed TargetVita is superior to the state-of-the-art vitamin-specific predictor, and an average improvement of 10% in terms of the Matthews correlation coefficient (MCC) was achieved over independent validation tests. The TargetVita web server and the datasets used are freely available for academic use at http://csbio.njust.edu.cn/bioinf/TargetVita or http://www.csbio.sjtu.edu.cn/bioinf/TargetVita.

Electronic supplementary material

The online version of this article (doi:10.1186/1471-2105-15-297) contains supplementary material, which is available to authorized users.     

Larval host records of butterflies in Japan

Using Japanese literature, we created a consolidated list of host records of butterflies in Japan. The list used the host records described in eight major illustrated reference books, two checklists, and 14 other pieces of literature. The presence of larvae on plants, the observation of larvae eating plants or insects in the field were considered as host records. We collected all species recorded in Japan. Scientific, family, and Japanese names of butterflies were consolidated using the BINRAN database (http://binran.lepimages.jp/). Scientific and Japanese names of host plants were based on the YList database (http://ylist.info/). If scientific names of host plants were not found in YList, we used scientific names based on The Plant List (http://www.theplantlist.org/). Family names of host plants were based on the Catalogue of Life database (http://www.catalogueoflife.org/). Scientific, family, and Japanese names of host insects were based on the MOKUROKU database (http://konchudb.agr.agr.kyushu-u.ac.jp/mokuroku/) for Hymenoptera and the catalogue of the Paraneoptera of Japan published by the Entomological Society of Japan for Hemiptera. We also provided the references of each host record and the original names described in the referred literature. Two datasets, HostDB and ReferenceDB, were created to include 3600 records of butterfly larval hosts in Japan, along with scientific and Japanese names of each species and a literature list. These datasets will be useful for basic and applied biological studies of butterflies. Data files are stored in the Ecological Research Data Archives (http://db.cger.nies.go.jp/JaLTER/ER_DataPapers/) and available from http://hostbj.lepumus.net/. These datasets are published under the Creative Commons License Attribution-ShareAlike 4.0 (CC BY-SA, https://creativecommons.org/licenses/by-sa/4.0/).     

糖尿病基层卫生适宜技术示范基地建设的实践探讨

针对基层医疗机构卫生服务技术水平和服务能力相对较低的现状,论述基层卫生适宜技术示范基地建设的重要性,并介绍糖尿病基层卫生适宜技术示范基地建设的经验以及取得的成效,为今后开展卫生适宜技术推广工作提供有益的借鉴。