中小型公立医院卫生人力资源配置存在问题与对策

随着医改的不断深入,中小型公立医院卫生人力资源配置面临着新的发展机遇和挑战,这就需要医院管理者对中小型公立医院的卫生人力资源进行深入思考。针对中小型公立医院卫生人力资源管理存在的诸多问题,从更新理念、人力规划、人才培养、构建团队、考核机制、契约机制以及医院文化等方面进行探讨,提出了卫生人力资源管理新策略。     

以实施新财会制度为契机构建医院财务管理平台

公立医院如何根据新《医院会计制度》和新《医院财务制度》,转变现有的医院财务管理体制,构建新型医院财务管理平台,已成为公立医院的内部管理体制改革的焦点。以江苏省人民医院为例,针对在新医改背景下,公立医院在构建新型医院财务管理平台过程中,如何处理新财会制度实施中面临的问题,做好新旧财会制度对接,提出应对措施和对策建议。     

基于JCI标准的医院质量管理体系建设

质量管理体系构建是医院质量管理的核心,也是“以病人为中心”的各项制度有效落实的根基。从剖析质量管理系统存在的问题入手,按照JCI医院评审标准,建立了全员参与、职责分明的四级质量管理体系及一体化的责任流程和监控体系;完善了不良事件上报管理体系,塑造了质量安全至上、精细化管理的价值理念;通过推广SPEAK方针,引导和鼓励患者及家属参与到质量持续改进中来。     

公立医院改革下护理管理的创新思路

公立医院改革是新医改的核心。加强护理工作是实现医改目标的重要措施之一,是构建和谐医患关系的客观要求。在推进公立医院改革的进程中,从医院层面开展“文化护理管理”、建立护理后勤、创新护理服务等方面的工作,探索公立医院护理管理创新思路。     

《医院财务制度（征求意见稿）》中公立医院国有资产管理的优化分析

国有资产管理是医院财务管理的重要内容,但我国公立医院国有资产管理存在着管理目标不当、范围界定不清、权责不明确、信息披露不全面等问题,无法适应新医改的要求。分析了这些不足并探讨了《医院财务制度（征求意见稿）》中公立医院国有资产管理在管理目标和管理范围方面的变化,提出落实医院独立法人地位、完善内部控制制度等改革方向。     

公立医院实施国家基本药物制度的可行性分析

在新医改的进程中,国家基本药物制度已在基层医疗卫生机构得到了很好的应用,而在公立医院改革过程中,国家基本药物制度的实施是否应该同步成为一个普遍关注的问题。文章通过对公立医院实施国家基本药物制度可行性的分析,阐明公立医院在改革的过程中应该切实推进国家基本药物制度,并提出了相应的制度保障措施。     

我院医院文化建设发展的途径探索

基于西安医学院第一附属医院医院文化建设实践,探索通过人才文化、创新文化、制度文化等主要途径,实现医院文化的落地生根,使医院文化为增强凝聚力、提高医疗质量和技术服务水平、提升医院核心竞争力发挥更加积极的作用。

     

我国公立医院开展岗位分析的探讨

自新医改方案公布以来,为顺应公立医院改革的精神,我国各级公立医院纷纷开展了岗位管理,这预示着我国医院的管理工作正逐步朝着科学管理的方向发展。其中,岗位分析是开展岗位管理工作的基础环节,就我国公立医院岗位分析的研究现状及其存在的问题展开探讨,并提出相关建议。

     

Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis

It has now been over twenty years since a novel herpesviral genome was identified in Kaposi's sarcoma biopsies. Since then, the cumulative research effort by molecular biologists, virologists, clinicians, and epidemiologists alike has led to the extensive characterization of this tumor virus, Kaposi's sarcoma-associated herpesvirus(KSHV; also known as human herpesvirus 8(HHV-8)), and its associated diseases. Here we review the current knowledge of KSHV biology and pathogenesis, with a particular emphasis on new and exciting advances in the field of epigenetics. We also discuss the development and practicality of various cell culture and animal model systems to study KSHV replication and pathogenesis.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

The structure, reproduction and taxonomy of Vidalia and Osmundaria (Rhodophyta, Rhodomelaceae)

Comprises species occurring mostly in subtidal habitats in tropical, subtropical and warm-temperate areas of the world. An analysis of the type species, V. spiralis (Sonder) Lamouroux ex J. Agardh, a species from Australia, establishes basic characters for distinguishing species in the genus. These characters are (1) branching patterns of thalli, (2) flat blades that may be spiralled on their axis, (3) width of the blade, (4) primary or secondary derivation of sterile and fertile branchlets and (5) position of sterile and fertile branchlets on the thalli. Application of the latter two characters provides an important basic method for separation of species into three major groups. Osmundaria , a genus known only in southern Australia, was studied in relation to Vidalia , and its separation from the Vidalia assemblage is not accepted. Species of Vidalia therefore are transferred to the older genus name, Osmundaria. Two new species, Osmundaria papenfussii and Osmundaria oliveae are described from Natal. Confusion in the usage of the epithet, Vidalia fimbriala Brown ex Turner has been clarified, and Vidalia gregaria Falkenberg, described as an epiphyte on Osmundaria pro/ifera Lamouroux, is revealed to be young branches of the host, Osmundaria prolifera.     

New or rare chromosome counts in Artemisia L. (Asteraceae, Anthemideae) and related genera from Kazakhstan

Fifteen chromosome counts of six Artemisia taxa and one species of each of the genera Brachanthemum, Hippolytia, Kaschgaria, Lepidolopsis and Turaniphytum are reported from Kazakhstan. Three of them are new reports, two are not consistent with previous counts and the remainder are confirmations of very scarce (one to four) earlier records. All the populations studied have the same basic chromosome number, x = 9, with ploidy levels ranging from 2x to 6x. Some correlations between ploidy level, morphological characters and distribution are noted.