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发酵工程课程实践性强且直接影响学生就业。近年来针对课程特点和授课对象,我们从教学理念、模块划分和授课方式等方面进行了改革和探索。课程改革以"能力培养为宗旨、课程模块为单元、多种教学资源为平台",探索了模块化、立体式教学模式,依据教学内容将理论课程划分为发酵工程设备、固体发酵、液体发酵和产品分离四个模块;实践教学紧密结合地方特色,以葡萄酒发酵全过程作为发酵基础实验,并通过工厂实习和科技作品试验提高学生的实践能力和创新意识;教学方式采用课堂教学、实验室操作和生产车间参观、实习相结合,实现课堂、实验室、车间立体结合,理论、实验与生产实践的有机链接。经三届共240多名学生的实践,证实对提高学生的社会实践能力和创新能力都有显著的促进作用。 相似文献
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“发酵工程原理与技术”是理工科高校生物专业的核心课程之一,具有较强的应用性和实践性。然而目前以线下教学为主的传统教学方式不利于学生对知识的理解和掌握。同时,该课程实验教学环节存在发酵设备更新不及时、缺乏大型工艺设备、易受场地限制等问题,严重影响实践教学效果。线上线下相结合的混合式教学模式是丰富教学资源和提升教学质量的重要手段。我们以“抗生素发酵生产工艺与工程实践”内容为例,基于虚拟仿真平台设计并构建虚拟仿真实验项目,同时结合课堂教学和实验室教学等线下教学方式,形成线上线下高度融合的混合式教学新模式。混合式教学强化了课堂教学与在线教学、虚拟实验与实体实验的有机结合,促进了学生扎实掌握理论知识和实验技能,培养了学生的创新精神和实践能力,提高了学生的综合素质。 相似文献
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"发酵工程实验"是生物工程专业的工程类重要主干课之一,是培养学生工程设计、工程实践和创新思维的重要课程。基于构思—设计—实现—运行(conceive—design—implement—operate,CDIO)理念,"发酵工程实验"通过构建模块化课程内容,以构思、设计、实现、运作的项目导向模块开展课程设计,进行目标导向的教学模式改革。以"发酵工程实验"课程为载体,将工程基础知识、发酵工程系统实践能力、团队合作能力、创新能力培养等融为一体。建立基于成果导向教育(outcome-based education,OBE)理念的学生学习效果评价体系,完成"发酵工程实验"课程教学任务。学生对改革后的"发酵工程实验"课程满意度明显提高,教学效果显著。 相似文献
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基于翻转课堂理论,结合以问题为基础的学习(Problem-based learning,PBL)教学法的"问题设置"、"问题解决"等特点与优势,构建了适用于实验操作类课程的教学模式,并以"水体疑遭粪便污染"这一实际问题作为情景进行的综合设计性实验为例,对高等教育环境相关本科专业基础课程"环境生物学实验"进行了创新性教学设计和实践。该教学模式通过课前准备、课中实施和课后反馈3个过程对实际问题进行分析和解决。课前准备包括教学团队针对实际问题设置若干相关实验场景,制作和搜集相应教学视频等教学资源,安排学生学习和完成任务;课中实施时教师直接指导学生进行实验操作,强调观察和记录实验现象,提出问题引导学生思考;课后反馈为学生提交实验结果与讨论、完成巩固练习和反馈问题等。实践表明,该教学模式在一线教学中行之有效,能取得较好的教学效果,值得推广。 相似文献
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介绍了探究教学模式在初中生物学实验教学中的实践与应用.课堂教学过程分为3个步骤:A.实验前讨论研究的问题并作实验设计;B.实验过程中获取数据;C.实验后学生讨论得出实验结论.整个教学过程中突出了学生的主动性和创造性,突出了如何将探究实验与学生获得的概念联系起来.突出了培养学生的逻辑型思维能力. 相似文献
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Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis
It has now been over twenty years since a novel herpesviral genome was identified in Kaposi's sarcoma biopsies. Since then, the cumulative research effort by molecular biologists, virologists, clinicians, and epidemiologists alike has led to the extensive characterization of this tumor virus, Kaposi's sarcoma-associated herpesvirus(KSHV; also known as human herpesvirus 8(HHV-8)), and its associated diseases. Here we review the current knowledge of KSHV biology and pathogenesis, with a particular emphasis on new and exciting advances in the field of epigenetics. We also discuss the development and practicality of various cell culture and animal model systems to study KSHV replication and pathogenesis. 相似文献
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正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases 相似文献
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Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme
responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare
the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show
that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by
distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of
demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least
one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of
the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable
potent antiproliferative synthetic drugs. 相似文献
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RICHARD E. NORRIS 《Botanical journal of the Linnean Society. Linnean Society of London》1991,106(1):1-40
Comprises species occurring mostly in subtidal habitats in tropical, subtropical and warm-temperate areas of the world. An analysis of the type species, V. spiralis (Sonder) Lamouroux ex J. Agardh, a species from Australia, establishes basic characters for distinguishing species in the genus. These characters are (1) branching patterns of thalli, (2) flat blades that may be spiralled on their axis, (3) width of the blade, (4) primary or secondary derivation of sterile and fertile branchlets and (5) position of sterile and fertile branchlets on the thalli. Application of the latter two characters provides an important basic method for separation of species into three major groups. Osmundaria , a genus known only in southern Australia, was studied in relation to Vidalia , and its separation from the Vidalia assemblage is not accepted. Species of Vidalia therefore are transferred to the older genus name, Osmundaria. Two new species, Osmundaria papenfussii and Osmundaria oliveae are described from Natal. Confusion in the usage of the epithet, Vidalia fimbriala Brown ex Turner has been clarified, and Vidalia gregaria Falkenberg, described as an epiphyte on Osmundaria pro/ifera Lamouroux, is revealed to be young branches of the host, Osmundaria prolifera. 相似文献
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JOAN VALUÈS MONTSERRAT TORRELL NÚRIA GARCIA JACAS 《Botanical journal of the Linnean Society. Linnean Society of London》2001,137(4):399-407
Fifteen chromosome counts of six Artemisia taxa and one species of each of the genera Brachanthemum, Hippolytia, Kaschgaria, Lepidolopsis and Turaniphytum are reported from Kazakhstan. Three of them are new reports, two are not consistent with previous counts and the remainder are confirmations of very scarce (one to four) earlier records. All the populations studied have the same basic chromosome number, x = 9, with ploidy levels ranging from 2x to 6x. Some correlations between ploidy level, morphological characters and distribution are noted. 相似文献