脂肪干细胞治疗下肢缺血的研究进展

下肢缺血性疾病是临床常见的严重危害中老年人健康的疾病之一。目前，临床针对下肢缺血性疾病的治疗方法多样，但远 期疗效欠佳，对于肢体严重缺血的患者往往需要进行截肢处理。脂肪干细胞（adipose-derived stemcells, ADSCs）作为再生医学用 于治疗下肢缺血的种子细胞具有广阔的应用前景。本文将对ADSCs 治疗下肢缺血的研究进展进行综述。     

犊牛沙门氏杆菌病预防与治疗

本文主要论述了犊牛沙门氏杆菌病的病原,传播途径,临床症状等等,结合这些情况给出预防和治疗该病的方法。     

植物基因转移方法

基因工程的诞生和发展是与基因转移方法的出现和发展分不开的。为了实现不同的目标，就需要各种各样的基因转移方法。一般来说，向植物中转移基因，存在的困难要比微生物和动物多些；但由于植物基因工程对作物改良的重要性，近年来获得了迅速发展，各种基因转移方法层出不穷。本文系统地介绍了现有的植物基因转移方法。     

中西医结合治疗五步蛇咬伤54例

五步蛇民间又称“棋盘蛇”、“尖吻蝮蛇”等 ,它是一种剧毒蛇 ,我院自 1 991年至 2 0 0 1年共收治五步蛇伤患者 5 4例 ,除 1例转上级专科医院 ,2例伤肢有肌肉萎缩后遗症外 ,其余全部治愈 ,现将资料报道如下。1　临床资料1 .1　一般资料　 5 4例患者均确诊为五步蛇咬伤 ,其中男 48例 ,女 6例 ;年龄最小 6岁 ,最大 67岁 ;咬伤部位绝大多数为四肢远端 ,而大腿和臀部各 1例。1 .2　病型分类　 ( 1 )轻型 2 4例 :伤口皮肤灼痛 ,局部轻度肿胀或肿胀超过 1个关节 ,伤口少许流血 ,全身症状有头昏、眼花、胸闷、视物模糊等。( 2 )重型 2 0例 :伤口剧…     

深度解读商业地图——呼吸器疾病治疗药

欧洲专利局（EPO）撤销了英国AstraZeneca公司的支气管哮喘治疗药富马酸福莫特罗（Formoterol Fumarate）和布地奈德（Budesonide）合剂Symbicort的重要专利之一。     

追溯山茱萸科植物的性状进化和生物地理学历史——方法选择的影响?

This study compares results on reconstructing the ancestral state of characters and ancestral areas of distribution in Cornaceae to gain insights into the impact of using different analytical methods. Ancestral character state reconstructions were compared among three methods (parsimony, maximum likelihood, and stochastic character mapping) using MESQUITE and a full Bayesian method in BAYESTRAITS and inferences of ancestral area distribution were compared between the parsimony-based dispersal-vicariance analysis (DIVA) and a newly developed maximum likelihood (ML) method. Results indicated that among the six inflorescence and fruit characters examined, "perfect" binary characters (no homoplasy, no polymorphism within terminals, and no missing data) are little affected by choice of method, while homoplasious characters and missing data are sensitive to methods used. Ancestral areas at deep nodes of the phylogeny are substantially different between DIVA and ML and strikingly different between analyses including and excluding fossils at three deepest nodes. These results, while raising caution in making conclusions on trait evolution and historical biogeography using conventional methods, demonstrate a limitation in our current understanding of character evolution and biogeography. The biogeographic history favored by the ML analyses including fossils suggested the origin and early radiation of Cornus likely occurred in the late Cretaceous and earliest Tertiary in Europe and intercontinental disjunctions in three lineages involved movements across the North Atlantic Land Bridge (BLB) in the early and mid Tertiary. This result is congruent with the role of NALB for post-Eocene migration and in connecting tropical floras in North America and Africa, and in eastern Asia and South America. However, alternative hypotheses with an origin in eastern Asia and early Trans-Beringia migrations of the genus cannot be ruled out.     

溶栓治疗急性脑梗塞的现状与进展

及时有效地治疗急性脑梗塞（ACI）是现代医学急需解决的一个问题，近年来，在这方面取得了许多进展，针对脑梗死周围缺血性半暗区的治疗已成为研究热点，本文就目前研究较多的超早期溶栓治疗和脑细胞保护剂的应用两方面作一综述。