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1.
Mauro Musto Daniele Cardinale Pietro Lucia Daniela Faraone 《Journal of applied animal welfare science : JAAWS》2016,19(3):217-233
This study evaluated whether showing a video of the different ways of raising goats for milk affected consumer acceptability. Four combinations, 2 Videos (intensive [INT] and semiextensive [SEM] system) × 2 Milk Types (semiskimmed [S] and whole [W] milk), were evaluated by 70 habitual consumers of goat milk, who scored their liking and purchase intention during blind (B), expected (E), and informed (I) acceptability sessions. In the B session, consumers tasted both milk types without information. S samples were preferred over W samples. In the E session, SEM video created high expectations in terms of milk liking and purchase intent, whereas the opposite happened when showing INT video. In the I session, consumers showed a clear preference for combinations created using SEM video, regardless of milk type. W-SEM and S-INT were worse (negative disconfirmation) and better (positive disconfirmation) than expected, respectively. A complete assimilation toward expectations occurred only for S-INT. INT video adversely affected the acceptability of S samples. Concerning purchase intent, W-SEM and S-SEM were worse than expected, but the assimilation was complete only for S-SEM: SEM video increased purchase intent for S samples. 相似文献
2.
Asymptotic distributions of kappa statistics and their differences with many raters,many rating categories and two conditions 下载免费PDF全文
Luca Grassano Guido Pagana Marco Daperno Enrico Bibbona Mauro Gasparini 《Biometrical journal. Biometrische Zeitschrift》2018,60(1):146-154
In clinical research and in more general classification problems, a frequent concern is the reliability of a rating system. In the absence of a gold standard, agreement may be considered as an indication of reliability. When dealing with categorical data, the well‐known kappa statistic is often used to measure agreement. The aim of this paper is to obtain a theoretical result about the asymptotic distribution of the kappa statistic with multiple items, multiple raters, multiple conditions, and multiple rating categories (more than two), based on recent work. The result settles a long lasting quest for the asymptotic variance of the kappa statistic in this situation and allows for the construction of asymptotic confidence intervals. A recent application to clinical endoscopy and to the diagnosis of inflammatory bowel diseases (IBDs) is shortly presented to complement the theoretical perspective. 相似文献
3.
Joana Darc Souza Chaves Jaqueline Lopes Damasceno Marcela Cristina Ferreira Paula Pollyanna Francielli de Oliveira Gustavo Chevitarese Azevedo Renato Camargo Matos Maria Cristina S. Lourenço Denise Crispim Tavares Heveline Silva Ana Paula Soares Fontes Mauro Vieira de Almeida 《Biometals》2015,28(5):845-860
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Morgenfeld Mauro M. Vater Catalina F. Alfano E. Federico Boccardo Noelia A. Bravo-Almonacid Fernando F. 《Transgenic research》2020,29(3):295-305
Transgenic Research - Chloroplast transformation has many potential advantages for the production of recombinant proteins in plants. However, it has been reported that chloroplast expression of... 相似文献
6.
Flow cytometry is a widely recognized method of rapidly assessing the ploidy and proliferation status of experimental and solid tumors. In the present work, a variety of human cancers from various sites (lung, head and neck, etc.), of traditional interest in our laboratory, have been analyzed. In agreement with a number of recent reports, a general heterogeneity of human solid tumors can be evidenced. In particular: (a) solid tumors are characterized by a variable degree of aneuploidy; (b) the internal structure of solid tumors is highly heterogeneous especially with respect to the fraction of aneuploid malignant cells and their distribution through the cycle phases; and (c) some solid tumors are also characterized by the presence, to a variable extent, in the tumor of mass of multiple cell clones. Static fluorimetry of Feulgen-stained (mitotic) single cells offers a way to confirm this kind of observations. 相似文献
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Fulvia Gloria-Bottini Nazzareno Lucarini Ricciotti Palmarino Mauro La Torre A. Amante E. Bottini 《Human genetics》1997,101(2):158-164
We have studied the pattern of association between the season of conception and cytosolic low molecular weight phosphotyrosine
phosphatase (ACP1) genetic polymorphism in 329 consecutively newborn infants from the population of Penne and 361 consecutively
newborn infants from the population of Rome. In addition, 329 mothers were studied in the population of Penne. A concordant,
highly significant association was observed in the two populations between ACP1 parameters and the season of conception of
newborn infants. The total activity of ACP1 shows a minimum in infants conceived in January–February and a maximum in those
conceived at the end of the solar year. Analysis of the joint mother-newborn ACP1 distribution in relation to the season of
fertilisation has shown that among mothers carrying ACP1*A (the allele showing the lowest activity), the proportion of newborns
carrying this allele is higher in those conceived in the first months of the year than in those conceived subsequently. Since
ACP1 probably functions as a phosphotyrosine phosphatase and as a flavin mononucleotide phosphatase, low activity could enhance
the metabolic rate and would be advantageous in a cold environment. The cycle of variation of ACP1 in infants follows the
cycle of solar illumination. It is possible that individuals who have a genetic background allowing them to adapt easily and
readily to seasonal demand are more successful in reproducing themselves. The population of zygotes conceived in a given season
would therefore reproduce the pattern of gene combination more fit for that season.
Received: 15 June 1997 / Accepted: 31 July 1997 相似文献
10.
Cristina Cereda Emanuela Leoni Pamela Milani Orietta Pansarasa Giuliano Mazzini Stefania Guareschi Elena Alvisi Andrea Ghiroldi Luca Diamanti Stefano Bernuzzi Mauro Ceroni Emanuela Cova 《PloS one》2013,8(10)
Several lines of evidence support the hypothesis of a toxic role played by wild type SOD1 (WT-SOD1) in the pathogenesis of sporadic amyotrophic lateral sclerosis (SALS). In this study we investigated both distribution and expression profile of WT-SOD1 in leukocytes from 19 SALS patients and 17 healthy individuals. Immunofluorescence experiments by confocal microscopy showed that SOD1 accumulates in the nuclear compartment in a group of SALS subjects. These results were also confirmed by western blot carried out on soluble nuclear and cytoplasmic fractions, with increased nuclear SOD1 level (p<0.05). In addition, we observed the presence of cytoplasmic SOD1 aggregates in agreement with an increased amount of the protein recovered by the insoluble fraction. A further confirmation of the overall increased level of SOD1 has been obtained from single cells analysis using flow cytometry as cells from SALS patients showed an higher SOD1 protein content (p<0.05). These findings add further evidence to the hypothesis of an altered WT-SOD1 expression profile in peripheral blood mononuclear cells (PBMCs) from patients with ALS suggesting that WT-SOD1 species with different degrees of solubility could be involved in the pathogenesis of the disease. 相似文献