OBE教育模式在生物工程专业英语教学中的应用研究CSCD

OBE教育模式是一种基于"学习产出"的教育新理念,已受到世界各国工程教育专业的认可,并成为工程教育质量评价的核心理念。为了提高生物工程专业英语教学质量,并与实际"学习产出"相结合,在生物工程专业英语教学中引入OBE教育理念,整合、归并和优化教学内容,并在教学中实施有效策略,切实提高学生专业英语综合运用能力。     

OBE教育模式在生物工程专业英语教学中的应用研究

OBE教育模式是一种基于"学习产出"的教育新理念,已受到世界各国工程教育专业的认可,并成为工程教育质量评价的核心理念。为了提高生物工程专业英语教学质量,并与实际"学习产出"相结合,在生物工程专业英语教学中引入OBE教育理念,整合、归并和优化教学内容,并在教学中实施有效策略,切实提高学生专业英语综合运用能力。     

英文医学班微生物学教学探讨

对英文医学班微生物学教学方法、教学内容、及教具改革方面进行了经验总结。对怎样使学生同时牢固地掌握医学基础知识和专业英语进行了探讨。为提高学生专业英语水平,为培养专业人才奠定良好的语言基础,提供了有效途径。     

医学实验动物学专业英语教学方法初探

本文结合作者参加医学实验动物专业英语教学和在美国访问学习经历,介绍了几种在专业英语教学中强化学生综合运用语言能力的方法,希望能够起到抛砖引玉的作用,为促进学生掌握该专业英语语言特点,提高学习效率和实际应用能力提供有益的参考。     

基于工程教育认证的“发酵工程”课程教学设计与实践

"发酵工程"是生物工程专业的核心主干课程,实践性和应用性较强。基于工程教育认证的产出导向理念,设定了"发酵工程"合理具体的课程目标,聚焦学生的工程知识掌握及问题分析、工程设计及研究能力培养。针对不同课程内容模块,以课程目标达成为导向,对教学内容及方法、教学设计与实施过程进行整合并优化,采用了多元化、注重课程形成性评价的考核方式。构建了课程目标达成评价模式,形成了"设计—实施—考核—评价—改进"闭环运行的课程质量保障体系。课程教学改革有效提高了学生理解、分析、设计、研究发酵工程问题的能力,增强了学生的科研兴趣和创新能力。     

植物学专业英语的特征和翻译——评《植物学词汇手册》

熟练掌握专业英语是开阔视野、了解国内外专业领域研究进展以及丰富专业知识的重要前提。专业英语的学习与应用和普通英语有所区别。在进行专业英语的学习和应用时,应重点关注并掌握专业英语的文体特征、词汇特点以及翻译技巧,这为提高专业英语应用能力,适应学术研究的国际大环境奠定坚实的语言基础,进而促进相关领域的研究与发展。     

国际工程教育认证下基于成果导向教育(OBE) 理念重构闭环式环境工程微生物学课程教学

工程教育专业认证是国际通行的工程教育质量保障制度,也是实现工程教育国际互认和工程师资格国际互认的重要基础。工程教育专业认证要求按照成果导向教育(Outcome Based Education,OBE)理念设计课程教学,教学过程要以学生为中心,最终形成持续改进的闭环式教学模式。环境工程微生物学是环境工程专业的核心课程之一,目前该课程的改革已经取得了一定成效,但其课程设置和教学方式等仍存在一些亟待解决的问题。本文就工程教育专业认证背景下,如何基于OBE理念明确环境工程微生物学对毕业要求贡献、设置课程目标、制定大纲、设计实验、跟踪评价学生、监控质量及持续改进等进行探讨,可为工程认证形势下课程的教学设计提供理论参考。     

生理学教学改革随想

范少光教授是我国著名生理学家,他五十余年致力于生理学教育事业,在生理学教育与教学改革的调研与实践上倾注了大量心血。他注重对学生进行专业素质教育及个性化培养,强调学生的专业英语学习,并主编了双语(中英文对照)人体生理学教科书。他主张人体生理学与临床相结合,并有独到见解。在他担任《生理科学进展》主编时,即创立了"生理科学与临床"栏目。范少光教授曾获"北京医科大学桃李奖"、北京市高等学校教学成果一等奖,以及北京市优秀教师等荣誉称号。他为人师表,勇于创新的精神,值得敬佩和学习。     

问题导向/翻转课堂教学在生物工程专业“化工原理”课程中的应用探索

新工科建设要求探索符合时代特征和工程教育规律的培养模式。针对“化工原理”课程特点和传统教学方法的局限性,将问题导向教学法与翻转课堂教学模式融合,用于生物工程等专业该课程的教学改革与实践。通过对课前知识学习、课中知识内化、课后巩固拓展3个阶段的系统教学设计,有效激发学生的学习兴趣和积极性,培养学生的自主学习能力和工程思维,取得了较好的教学效果,可为农业院校化工原理及食品工程原理课程建设和工程人才培养提供参考和借鉴。     

基于OBE理念的《生物化学》教学改革实践与探索

以成果导向教育理念为指导,结合《生物化学》课程的教学现状,本次教学改革将OBE理念运用到《生物化学》课程教学实践,从优化教学内容、引入典型案例、实现在线学习、引入学科前沿等多个方面设计实施课程改革。上述改革措施的实施有效解决了该课程以往教学中存在的问题,充分调动了学生的主观能动性,提升了学生解决问题的能力以及专业英语素养,大大提高了学生的学习成效。     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.