促进我国环境微生物学的发展—“第十次全国环境微生物学术研讨会”专刊序言

我国是世界上环境污染最为严重的国家之一,环境治理工作日趋重要.随着分子生物学技术的发展,在环境微生物学领域的科研工作者的不懈努力下,我国在环境微生物学方面取得了许多重要成果,使微生物在环境保护中发挥着越来越重要的作用.为了展现国内环境微生物科研工作者取得的最新进展,<微生物学通报>针对"第十次全国环境微生物学术研讨会"组织出版了这期"环境微生物专刊",期望该专刊的出版有助于我国环境微生物学相关领域的交流和发展.     

快速发展中的环境微生物科学与技术—“第十二次全国环境微生物学学术研讨会”专刊序言

第十二次全国环境微生物学术研讨会于2009年11月在武汉华中科技大学顺利召开,本次会议围绕"环境微生物与人类健康"的主题,在环境微生物学前沿、微生物与环境健康及人类健康、环境微生物资源挖掘与利用,以及环境微生物技术与环境污染防治、生态修复、废弃物资源化利用和再生能源等诸多领域展开深入研讨,充分反映了我国环境微生物学界取得的最新进展,为了展现国内环境微生物及相关交叉领域科研工作者取得的最新进展,《微生物学通报》针对"第十二次全国环境微生物学术研讨会"组织出版了这期"环境微生物专刊",期望该专刊的出版有助于促进我国环境微生物学相关领域的交流和发展。     

促进我国环境微生物学的发展—“第十次全国环境微生物学术研讨会”专刊序言

我国是世界上环境污染最为严重的国家之一, 环境治理工作日趋重要。随着分子生物学技术的发展, 在环境微生物学领域的科研工作者的不懈努力下, 我国在环境微生物学方面取得了许多重要成果, 使微生物在环境保护中发挥着越来越重要的作用。为了展现国内环境微生物科研工作者取得的最新进展,《微生物学通报》针对“第十次全国环境微生物学术研讨会” 组织出版了这期“环境微生物专刊”, 期望该专刊的出版有助于我国环境微生物学相关领域的交流和发展。     

我国环境微生物学发展现状与面临的挑战—“第十三次全国环境微生物学学术研讨会”专刊序言

第十三次全国环境微生物学术研讨会于2010年11月在南京大学顺利召开,本次会议围绕"环境微生物与社会发展"的主题,在环境微生物学研究前沿、环境微生物与节能减排、环境微生物与气候变化、环境微生物资源发掘与应用、环境保护工程、污染环境生物修复、蓝藻水华衍生污染物与生态风险等诸多领域阐述了最新研究进展并展开了深入的研讨。为了展现国内环境微生物及相关交叉领域科研工作者取得的最新进展,《微生物学通报》针对"第十三次全国环境微生物学学术研讨会"组织出版了这期"环境微生物专刊",期望该专刊的出版有助于促进我国环境微生物学相关领域的交流与发展。     

创新发展中的我国环境微生物学研究

2016年11月,"第十九次全国环境微生物学学术研讨会"在重庆市召开。八百多名国内外与会者围绕环境微生物学前沿基础、污染物降解与微生物修复、废弃物资源化利用与环境生物技术、微生物生态、微生物资源与分布等五个主题进行了多种形式的交流讨论。会议充分展现了我国环境微生物学研究、应用进展和良好的发展前景,其中部分领域的研究工作国际领先。《微生物学通报》针对本次研讨会组织出版了本期《环境微生物学主题刊》,旨在展示我国环境微生物学最新的研究进展和成果,促进环境微生物学及相关学科的交流和发展。     

抓住机遇,迎接挑战 维系我国环境微生物事业健康有序发展—“第十四次全国环境微生物学学术研讨会”专刊序言

"第十四次全国环境微生物学术研讨会暨简浩然先生诞辰100周年纪念"于2011年11月25 28日在福建厦门隆重召开,本次会议围绕"环境微生物与生态保护"的主题,在环境微生物学研究前沿、微生物资源发掘与应用、节能减排、循环经济、污染环境生物修复与环境保护工程等诸多领域阐述了最新研究进展并展开了深入的研讨。为了展现国内环境微生物及相关交叉领域科研工作者取得的最新进展,《微生物学通报》针对"第十四次全国环境微生物学学术研讨会"组织出版了这期"环境微生物专刊",期望该专刊的出版有助于促进我国环境微生物学相关领域的交流与发展。     

抓住机遇，迎接挑战维系我国环境微生物事业健康有序发展

“第十四次全国环境微生物学术研讨会暨简浩然先生诞辰100周年纪念”于2011年11月25?28日在福建厦门隆重召开, 本次会议围绕“环境微生物与生态保护”的主题, 在环境微生物学研究前沿、微生物资源发掘与应用、节能减排、循环经济、污染环境生物修复与环境保护工程等诸多领域阐述了最新研究进展并展开了深入的研讨。为了展现国内环境微生物及相关交叉领域科研工作者取得的最新进展, 《微生物学通报》针对“第十四次全国环境微生物学学术研讨会”组织出版了这期“环境微生物专刊”, 期望该专刊的出版有助于促进我国环境微生物学相关领域的交流与发展。     

微生物菌种资源及其特性是国内环境微生物研究热点

环境微生物研究是我国微生物界发展最快、也是最活跃的重要领域之一.根据《微生物学通报》发表论文的统计数据,2014年本刊共发表文章308篇,其中发表数量名列前茅的是环境微生物领域(40篇),紧随其后的是农业微生物(30篇)和工业微生物(29篇).在环境微生物研究工作中,微生物菌种资源及其特性相关文章以16篇位居榜首.     

快速发展的我国环境微生物学——“第十一次全国环境微生物学学术研讨会”专刊序言

2008年11月“第十一次全国环境微生物学学术研讨会”在江苏无锡顺利召开, 这次大会充分反映了我国环境微生物学界取得的最新进展。为了展现我国环境微生物学工作者取得的新成果,《微生物学通报》在08年“环境微生物专刊”的基础上, 针对“第十一次全国环境微生物学学术研讨会”组织出版了新一期专刊, 期望该专刊的出版能进一步推动我国环境微生物学相关领域的交流和发展。     

新时代下的我国环境微生物学研究

环境微生物学作为微生物学与环境科学相结合的交叉学科，已经在环境污染物质降解、废弃物资源化利用和元素生物地球化学循环等方面发挥着重要作用。《微生物学通报》本期推出的“环境微生物学主题刊”报道了研究报告11篇、专论与综述12篇，内容涵盖环境微生物与环境工程、环境微生物生理学及生物制剂、环境微生物资源的发掘与利用、环境微生物学方法学、环境微生物遗传与生理、环境污染修复与微生物多样性、环境微生物与环境健康、环境微生物学研究前沿等应用领域，期望该主题刊的出版有助于加强我国环境微生物学研究者间的交流与合作，推动环境微生物学学科的进一步发展。     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.