芫菁科不同种类成虫体内斑蝥素的含量

芫菁体内含有斑蝥素，是一种重要的药用昆虫。近年来我国对斑蝥素的临床应用研究表明：斑蝥素及其衍生物对治疗原发性肝癌疗效显著。为了摸清我国芫菁科昆虫的自然资源和虫体内斑蝥素的含量，作者调查了不同地区、不同寄主植物上芫菁科昆虫的种类分布，并利用气相色谱内标法测定了不同性别以及交尾高峰前后的芫菁成虫体内斑蝥素的含量。发现雄性成虫体内斑蝥素的含量均高于雌性成虫。交配高峰后的芫菁雌性成虫体内斑蝥素含量高于交配高峰前的芫菁雌性成虫体内斑蝥素含量。

The natural resource and content of cantharidin in the adult of meloids in China

Cantharidin, a terpenoid substance, is contained in a group of widely spreading insects—the blister beetles (Coleoptera: Meloidae) in the world. It has been used medicinally for its irritant proprieties, both in China and in the western countries for a long time. In China, in recent years, the clinical practice of cantharidin and its derivatives proved their curative effect on the primary liver cancer and some of other tumors to certain extent. In order to conserve and use the resource of Meloidae more effectively, an extensive survey of Meloidae and quantitative determinations of cantharidin in the adult of beetles were carried out. A total of 38 specimens in 9 species was collected on various host-plants from different districts in China. The cantharidin was isolated by HCl extraction of dry bodies of adults and quantitatively analyzed by GC with internal standard. The results showed that the maximum content of cantharidin was 2.932% of dry body in male Mylabris mongolica from Inner Mongolia Autonomous Region. All specimens contain cantharidin and the content of cantharidin was higher in the male than that in the female of the same species. In addition, the cantharidin content in the female collected after the copulation peak was higher than that before copulation peak, this suggested that transfer of cantharidin from male to female occurred during copulation.