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1.
There is a multitude of ecosystem service classifications available within the literature, each with its own advantages and drawbacks. Elements of them have been used to tailor a generic ecosystem service classification for the marine environment and then for a case study site within the North Sea: the Dogger Bank. Indicators for each of the ecosystem services, deemed relevant to the case study site, were identified. Each indicator was then assessed against a set of agreed criteria to ensure its relevance and applicability to environmental management. This paper identifies the need to distinguish between indicators of ecosystem services that are entirely ecological in nature (and largely reveal the potential of an ecosystem to provide ecosystem services), indicators for the ecological processes contributing to the delivery of these services, and indicators of benefits that reveal the realized human use or enjoyment of an ecosystem service. It highlights some of the difficulties faced in selecting meaningful indicators, such as problems of specificity, spatial disconnect and the considerable uncertainty about marine species, habitats and the processes, functions and services they contribute to. 相似文献
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Regulators face the problem of ensuring that wetland functions that are lost due to permitting actions are restored via mitigation of those impacts. While there has been considerable study of wetland function, little of it has been directed toward the practical assessment of mitigation success. Development of quantitatively based rapid assessment methods would provide valuable assistance to the regulatory community. Regional and local goal setting, including a determination of whether strict in-kind restoration or restoration of habitat balance is preferable, is needed to ensure that the ecological health of the area is restored to the greatest extent possible. 相似文献
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The spectra of k-mer frequencies can reveal the structures and evolution of genome sequences. We confirmed that the trimodal spectrum of 8-mers in human genome sequences is distinguished only by CG2, CG1 and CG0 8-mer sets, containing 2,1 or 0 CpG, respectively. This phenomenon is called independent selection law. The three types of CG 8-mers were considered as different functional elements. We conjectured that (1) nucleosome binding motifs are mainly characterized by CG1 8-mers and (2) the core structural units of CpG island sequences are predominantly characterized by CG2 8-mers. To validate our conjectures, nucleosome occupied sequences and CGI sequences were extracted, then the sequence parameters were constructed through the information of the three CG 8-mer sets respectively. ROC analysis showed that CG1 8-mers are more preference in nucleosome occupied segments (AUC > 0.7) and CG2 8-mers are more preference in CGI sequences (AUC > 0.99). This validates our conjecture in principle. 相似文献
4.
Yanli Zhang Lina Wang Wenhao Zhou Huijun Wang Jin Zhang Shanshan Deng Weihua Li Huawei Li Zuohua Mao Duan Ma 《Developmental biology》2013
Tissue factor pathway inhibitor-2 (Tfpi-2) is an important serine protease inhibitor in the extracellular matrix (ECM), but its precise physiological significance remains unknown. This work is part of a series of studies intended to investigate functional roles of Tfpi-2 and explore the underlying molecular mechanisms. First, we cloned and identified zebrafish Tfpi-2 (zTfpi-2) as an evolutionarily conserved protein essential for zebrafish development. We also demonstrated that ztfpi-2 is mainly expressed in the central nervous system (CNS) of zebrafish, and embryonic depletion of ztfpi-2 caused severe CNS defects. In addition, changes of neural markers, including pax2a, egr2b, huC, ngn1, gfap and olig2, confirmed the presence of developmental abnormalities in the relevant regions of ztfpi-2 morphants. Using microarray analysis, we found that members of the Notch pathway, especially her4 and mib, which mediate lateral inhibition in CNS development, were also downregulated. Intriguingly, both her4 and mib were able to partially rescue the ztfpi-2 morphant phenotype. Furthermore, Morpholino knockdown of ztfpi-2 resulted in upregulation of neuronal markers while downregulation of glial markers, providing evidence that the Notch pathway is probably involved in ztfpi-2-mediated CNS development. 相似文献
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双孔钾离子通道是一种背景钾离子通道,广泛分布于各种兴奋和非兴奋细胞中,并具有许多重要的生理功能。TASK-1是双孔钾离子通道家族的重要一员,它对缺氧和细胞外酸化敏感,参与形成心肌动作电位平台期,调节呼吸、肺动脉平滑肌收缩和醛固酮的分泌,并且是麻醉剂的作用靶点,人们不断对其进行研究并取得了很多重要结果,本文将概述双孔钾通道TASK-1的研究进展。 相似文献
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The four canonical bases that make up genomic DNA are subject to a variety of chemical modifications in living systems. Recent years have witnessed the discovery of various new modified bases and of the enzymes responsible for their processing. Here, we review the range of DNA base modifications currently known and recent advances in chemical methodology that have driven progress in this field, in particular regarding their detection and sequencing. Elucidating the cellular functions of modifications remains an ongoing challenge; we discuss recent contributions to this area before exploring their relevance in medicine. 相似文献
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哺乳类两大嗅觉系统功能的研究进展 总被引:1,自引:0,他引:1
近年来对于嗅觉系统的研究已成为动物学研究的热点之一,本文通过对以往关于哺乳类两大嗅觉系统功能的研究进行总结和回顾,对目前犁鼻器系统(VOE-AOB)和主嗅觉系统(MOE-MOB)功能结论上的争议做了初步探讨。通过概括和总结,发现目前对两大嗅觉系统功能还存在争议,其原因可能有以下几点:以前的研究方法上可能有不完善之处;不同的研究采用的物种不同,结论上的争议也许与不同物种间存在种间差异有关;动物的社会经验对研究结论可能也有一定影响。希望通过本文能进一步促进今后此方面的研究。 相似文献
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为揭示生态功能保护区归一化植被指数(NDVI)与气候因子相关性, 为今后该区域植被动态监测提供有用的信息, 该研究基于2000-2015年MODIS NDVI数据和逐月格点降水与气温数据, 采用生态功能保护区和像元两种空间尺度, 应用线性倾向分析、偏相关分析、复相关分析等方法研究了46个生态功能保护区NDVI变化及其与气候因子的关系, 在此基础上基于相关系数显著性水平对生态功能保护区NDVI动态进行了气候因子驱动分区。主要结果: (1)生态功能保护区NDVI总体呈增加趋势, 其增率加权平均值为0.045·a-1。像元分析表明, NDVI显著增加的区域主要分布在中部和东北部。(2)生态功能保护区NDVI与降水的偏相关系数在-0.30-0.72之间, 在32个分区呈正相关关系。NDVI与气温的偏相关性在-0.36-0.92之间, 在39个分区呈正相关关系。像元分析表明, 50.6%的像元NDVI与降水呈显著正偏相关关系, 主要分布在东北及西北地区。64.6%的像元NDVI与气温呈显著正偏相关关系, 主要分布在东北及青藏高原北缘地区。(3)气温-降水强驱动型是主要驱动类型, 占总面积的38.7%; 气温驱动型为次要驱动类型, 占27.3%; 非气候因子驱动型占17.6%。以上结果表明, 生态功能保护区NDVI与气温、降水气候因子改变具有显著相关性, 气候因子驱动的地区共占82.4%。研究气候变暖背景下生态功能保护区NDVI变化及其对气候因子的响应, 对于认识该区植被动态变化规律具有重要作用。 相似文献