全文获取类型
收费全文 | 394987篇 |
免费 | 44181篇 |
国内免费 | 172篇 |
出版年
2018年 | 4021篇 |
2017年 | 3768篇 |
2016年 | 5652篇 |
2015年 | 8330篇 |
2014年 | 9635篇 |
2013年 | 13064篇 |
2012年 | 15467篇 |
2011年 | 15593篇 |
2010年 | 10373篇 |
2009年 | 9361篇 |
2008年 | 13427篇 |
2007年 | 13906篇 |
2006年 | 13114篇 |
2005年 | 12674篇 |
2004年 | 12631篇 |
2003年 | 12158篇 |
2002年 | 11831篇 |
2001年 | 15084篇 |
2000年 | 14911篇 |
1999年 | 12273篇 |
1998年 | 4949篇 |
1997年 | 4677篇 |
1996年 | 4416篇 |
1995年 | 4380篇 |
1994年 | 4366篇 |
1993年 | 4307篇 |
1992年 | 10322篇 |
1991年 | 9890篇 |
1990年 | 9647篇 |
1989年 | 9325篇 |
1988年 | 8730篇 |
1987年 | 8319篇 |
1986年 | 7527篇 |
1985年 | 7703篇 |
1984年 | 6542篇 |
1983年 | 5682篇 |
1982年 | 4657篇 |
1981年 | 4152篇 |
1980年 | 3918篇 |
1979年 | 6382篇 |
1978年 | 4851篇 |
1977年 | 4540篇 |
1976年 | 4228篇 |
1975年 | 4492篇 |
1974年 | 4888篇 |
1973年 | 4860篇 |
1972年 | 4471篇 |
1971年 | 4167篇 |
1970年 | 3513篇 |
1969年 | 3413篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Early environment influences later performance in fishes 总被引:1,自引:0,他引:1
Conditions fish encounter during embryogenesis and early life history can leave lasting effects not only on morphology, but also on growth rate, life‐history and behavioural traits. The ecology of offspring can be affected by conditions experienced by their parents and mother in particular. This review summarizes such early impacts and their ecological influences for a variety of teleost species, but with special reference to salmonids. Growth and adult body size, sex ratio, egg size, lifespan and tendency to migrate can all be affected by early influences. Mechanisms behind such phenotypically plastic impacts are not well known, but epigenetic change appears to be one central mechanism. The thermal regime during development and incubation is particularly important, but also early food consumption and intraspecific density can all be responsible for later life‐history variation. For behavioural traits, early experiences with effects on brain, sensory development and cognition appear essential. This may also influence boldness and other social behaviours such as mate choice. At the end of the review, several issues and questions for future studies are given. 相似文献
2.
Helices are the most common elements of RNA secondary structure. Despite intensive investigations of various types of RNAs, the evolutionary history of the formation of new helices (novel helical structures) remains largely elusive. Here, by studying the nuclear ribosomal Internal Transcribed Spacer 2 (ITS2), a fast-evolving part of the eukaryotic nuclear ribosomal operon, we identify two possible types of helix formation: one type is “dichotomous helix formation”—transition from one large helix to two smaller helices by invagination of the apical part of a helix, which significantly changes the shape of the original secondary structure but does not increase its complexity (i.e., the total length of the RNA). An alternative type is “lateral helix formation”—origin of an extra helical region by the extension of a bulge loop or a spacer in a multi-helix loop of the original helix, which does not disrupt the pre-existing structure but increases RNA size. Moreover, we present examples from the RNA sequence literature indicating that both types of helix formation may have implications for RNA evolution beyond ITS2. 相似文献
3.
4.
An insufficiently known bivalve and gastropod assemblage from the Early-Middle Miocene (Tarkhanian-Chokrakian) of northern Sinop Province (Turkey), is analyzed. Environments of the assemblage are reconstructed for the Chokrakian as subtidal, with prevailing lime and sandy bottom and good aeration, and partially well vegetated. Impoverishment of the mollusk biocoenose in this part of the marine basin (only 18 bivalve and 22 gastropod species recorded) compared to other areas, including the closest regions, Bulgaria on the west and Georgia on the east, is emphasized. The relatively low diversity of the fauna is probably connected not only with insufficient collecting, but with special hydrological conditions. A special aspect of the fauna is highlighted by the presence of the bivalve Circomphalus foliaceolamellosus subplicatus (Orb.), which is rare in the Chokrakian. 相似文献
5.
Multistep Photoluminescence Decay Reveals Dissociation of Geminate Charge Pairs in Organolead Trihalide Perovskites 下载免费PDF全文
Ramūnas Augulis Marius Franckevičius Vytautas Abramavičius Darius Abramavičius Shaik Mohammed Zakeeruddin Michael Grätzel Vidmantas Gulbinas 《Liver Transplantation》2017,7(17)
Charge carrier dynamics in organolead iodide perovskites is analyzed by employing time‐resolved photoluminescence spectroscopy with several ps time resolution. The measurements performed by varying photoexcitation intensity over five orders of magnitude enable separation of photoluminescence components related to geminate and nongeminate charge carrier recombination and to address the dynamics of an isolated geminate electron–hole pair. Geminate recombination dominates at low excitation fluence and determines the initial photoluminescence decay. This decay component is remarkably independent of the material structure and experimental conditions. It is demonstrated that dependences of the geminate and nongeminate radiative recombination components on excitation intensity, repetition rate, and temperature, are hardly compatible with carrier trapping and exciton dissociation models. On the basis of semiclassical and quantum mechanical numerical calculation results, it is argued that the fast photoluminescence decay originates from gradual spatial separation of photogenerated weakly bound geminate charge pairs. 相似文献
6.
Benjamin B Wheatley Gregory M Odegard Kenton R Kaufman Tammy L Haut Donahue 《Biomechanics and modeling in mechanobiology》2017,16(3):1011-1022
The passive properties of skeletal muscle are often overlooked in muscle studies, yet they play a key role in tissue function in vivo. Studies analyzing and modeling muscle passive properties, while not uncommon, have never investigated the role of fluid content within the tissue. Additionally, intramuscular pressure (IMP) has been shown to correlate with muscle force in vivo and could be used to predict muscle force in the clinic. In this study, a novel model of skeletal muscle was developed and validated to predict both muscle stress and IMP under passive conditions for the New Zealand White Rabbit tibialis anterior. This model is the first to include fluid content within the tissue and uses whole muscle geometry. A nonlinear optimization scheme was highly effective at fitting model stress output to experimental stress data (normalized mean square error or NMSE fit value of 0.993) and validation showed very good agreement to experimental data (NMSE fit values of 0.955 and 0.860 for IMP and stress, respectively). While future work to include muscle activation would broaden the physiological application of this model, the passive implementation could be used to guide surgeries where passive muscle is stretched. 相似文献
7.
Altitudinal distribution limits of aquatic macroinvertebrates: an experimental test in a tropical alpine stream 下载免费PDF全文
PHILIP B. MADSEN ANDRÉS MORABOWEN PATRICIO ANDINO RODRIGO ESPINOSA SOPHIE CAUVY‐FRAUNIÉ OLIVIER DANGLES DEAN JACOBSEN 《Ecological Entomology》2015,40(5):629-638
1. Temperature and oxygen are recognised as the main drivers of altitudinal limits of species distributions. However, the two factors are linked, and both decrease with altitude, why their effects are difficult to disentangle. 2. This was experimentally addressed using aquatic macroinvertebrates; larvae of Andesiops (Ephemeroptera), Claudioperla, (Plecoptera), Scirtes (Coleoptera) and Anomalocosmoecus (Trichoptera), and the amphipod Hyalella in an Ecuadorian glacier‐fed stream (4100–4500 m a.s.l.). The following were performed: (i) quantitative benthic sampling at three sites to determine altitudinal patterns in population densities, (ii) transplants of the five taxa upstream of their natural altitudinal limit to test the short‐term (14 days) effect on survival, and (iii) in situ experiments of locomotory activity as a proxy for animal response to relatively small differences in temperature (5 °C vs. 10 °C) and oxygen saturation (55% vs. 62%). 3. The transplant experiment reduced survival to a varying degree among taxa, but Claudioperla survived well at a site where it did not naturally occur. In the in situ experiment, Scirtes and Hyalella decreased their activity at lower oxygen saturation, whereas Andesiops and Anomalocosmoecus did so at a low temperature. The decrease in activity from a high to a low temperature and oxygen for the five taxa was significantly correlated with their mortality in the transplant experiment. 4. Together the present experiments indicate that even relatively small differences in temperature and oxygen may produce effects explaining ecological patterns, and depending on the taxon, either water temperature or oxygen saturation, without clear interacting effects, are important drivers of altitudinal limits. 相似文献
8.
9.
Galina Belostotskaya Alexey Nevorotin Michael Galagudza 《Cell cycle (Georgetown, Tex.)》2015,14(19):3155-3162
Cardiac stem cells are described in a number of mammalian species including humans. Cardiac stem cell clusters consisting of both lineage-negative and partially committed cells are generally identified between contracting cardiac myocytes. In the present study, c-kit+, Sca+, and Isl1+ stem cells were revealed to be located inside the sarcoplasm of cardiac myocytes in myocardial cell cultures derived from newborn, 20-, and 40-day-old rats. Intracellularly localized cardiac stem cells had a coating or capsule with a few pores that opened into the host cell sarcoplasm. The similar structures were also identified in the suspension of freshly isolated myocardial cells (ex vivo) of 20- and 40-day-old rats. The results from this study provide direct evidence for the replicative division of encapsulated stem cells, followed by their partial cardiomyogenic differentiation. The latter is substantiated by the release of multiple transient amplifying cells following the capsule rupture. In conclusion, functional cardiac stem cells can reside not only exterior to but also within cardiomyocytes. 相似文献
10.