全文获取类型
收费全文 | 1174篇 |
免费 | 115篇 |
出版年
2023年 | 8篇 |
2022年 | 3篇 |
2021年 | 22篇 |
2020年 | 14篇 |
2019年 | 19篇 |
2018年 | 29篇 |
2017年 | 27篇 |
2016年 | 33篇 |
2015年 | 73篇 |
2014年 | 75篇 |
2013年 | 93篇 |
2012年 | 93篇 |
2011年 | 61篇 |
2010年 | 42篇 |
2009年 | 59篇 |
2008年 | 59篇 |
2007年 | 57篇 |
2006年 | 56篇 |
2005年 | 56篇 |
2004年 | 50篇 |
2003年 | 42篇 |
2002年 | 59篇 |
2001年 | 11篇 |
2000年 | 19篇 |
1999年 | 12篇 |
1998年 | 19篇 |
1997年 | 18篇 |
1996年 | 15篇 |
1995年 | 21篇 |
1994年 | 13篇 |
1993年 | 9篇 |
1992年 | 13篇 |
1991年 | 12篇 |
1990年 | 9篇 |
1989年 | 6篇 |
1988年 | 4篇 |
1987年 | 7篇 |
1985年 | 4篇 |
1984年 | 3篇 |
1982年 | 4篇 |
1981年 | 4篇 |
1979年 | 3篇 |
1976年 | 6篇 |
1975年 | 4篇 |
1974年 | 4篇 |
1973年 | 4篇 |
1969年 | 8篇 |
1967年 | 5篇 |
1966年 | 4篇 |
1965年 | 3篇 |
排序方式: 共有1289条查询结果,搜索用时 19 毫秒
1.
2.
The non-recombining nature of the Y-chromosome determines the non-independence of alleles between loci. The evolution of short tandem repeat (STR) loci in the Y-chromosome is the result of different factors such as differential mutation rates, mutation modes, gene conversion, selection and demographic processes. The degree of correlation between loci is dependent on the magnitude of these processes. The simulation of data is a routine tool used for testing hypotheses in population and evolutionary studies. The most basic parameters hitherto used in lineage haplotype simulations are the allele frequency distributions and mutation rates, assuming either full independence or linkage between loci. In this study we introduce use of the Spearman correlation coefficient to estimate the degree of dependence between non-recombining loci. Then, both the interdependence between loci and the allele frequency distributions at multi-allelic loci are incorporated in an algorithm for simulating haplotypes. We illustrate the method using published and unpublished Y-chromosome STR data. 相似文献
3.
4.
PM Visscher 《遗传、选种与进化》1995,27(4):335-345
5.
Summary The activated dimonophosphate of 3-deoxyadenosine (cordycepin) undergoes oligomerization to produce a new family of pyrophosphate-linked oligomers in which the average repeating unit involves a nine-atom structural group. The presence of a poly(U) template increase the relative yields of higher oligomers, although the template-free reaction is itself extremely efficient.For the previous paper in this series see Schwartz et al. (1987) 相似文献
6.
J. Visscher R. van der Woerd C. G. Bakker Alan W. Schwartz 《Origins of life and evolution of the biosphere》1989,19(1):3-6
Evidence is presented that a poly(U) template selectively favors the oligomerization of the activated, 3–5 pyrophosphate-linked dimer pdAppdAp, in comparison with the 3–3 and 5–5 linked dimers. In the absence of poly(U), the 5–5linked dimer is the most reactive, and chains are formed which are more than 60 monomer units in length.Nucleic Acid-Like Structures V. For the previous paper in this series see Visscher and Schwartz (1988). 相似文献
7.
Ralf Steudel Gabriele Holdt Pieter T. Visscher Hans van Gemerden 《Archives of microbiology》1990,153(5):432-437
Cultures of Chromatium vinosum, devoid of sulfur globules, were supplemented with sulfide and incubated under anoxic conditions in the light. The concentrations of sulfide, polysulfides, thiosulfate, polythionates and elemental sulfur (sulfur rings) were monitored for 3 days by ion-chromatography and reversed-phase HPLC. While sulfide disappeared rapidly, thiosulfate and elemental sulfur (S6, S7 S8 rings) were formed. After sulfide depletion, the concentration of thiosulfate decreased fairly rapidly, but elemental sulfur was oxidized very slowly to sulfate. Neither polysulfides (S
x
2–
), polythionates (SnO
6
2–
, n=4–6), nor other polysulfur compounds could be detected, which is in accordance with the fact that sulfide-grown cells were able to oxidize polysulfide without lag. The nature of the intracellular sulfur globules is discussed. 相似文献
8.
Koen Martens 《Hydrobiologia》1985,124(1):81-83
Salinity tolerance, and the effects of temperature upon it, of the Australian ostracod Mytilocypris henricae (Chapman) was determined in direct transfer experiments using adults. Animals were subjected to a combination of 11 salinities (ranging between 0.0 g · 1–1 and 45.0 g · 1–1) and 4 temperatures (10, 15, 20 and 25 °C). Survival was analysed using two statistical techniques: the logit linear model and the proportional hazards model. Results show that both salinity and temperature have a significant effect on survival, but there is no significant interaction between temperature and salinity. 相似文献
9.
10.
Lactate dehydrogenase subunits B and A are produced by genes at separate loci. LDH-1, the most anodal of the five isozymes observed after gel electrophoresis, is composed of four B subunits. It has recently been shown that the LDH-1s of most primates are electrophoretically the same. N. coucang (slow loris) is one of the exceptions, possessing an LDH-1 which migrates more slowly than that common to most other primates. We have observed in some members of N. coucang a band at the site of the common primate LDH-1 in addition to the LDH-1 normally present. Since one of the animals in which this observation was made was heterozygous at the LDH B locus, we concluded that in N. coucang two gene loci coding for the B polypeptide are probably present.This investigation was supported in part by contract AF 29 (600)-5587 and NSF grant GB-7426. 相似文献