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为探讨针刀联合曲安奈德、正清风痛宁、利多卡因治疗肩周炎的临床疗效及安全性分析,本研究选取2016年1月至2017年12月来东南大学附属中大医院疼痛科就诊肩周炎患者120例,随机数字表法分为药物治疗组40例(曲安奈德+正清风痛宁+利多卡因+臭氧治疗),针刀治疗组40例,综合治疗组40例(曲安奈德+正清风痛宁+利多卡因+臭氧+针刀治疗),对比分析各组治疗前后肩关节功能评分、视觉模拟评分法(visual analogue score, VAS)评分、不良反应发生率。结果显示,组内比较,3组治疗后VAS和肩关节功能评分与治疗前比较,差异具有统计学意义(p<0.001)。组间比较,治疗前3组VAS和肩关节功能评分比较,差异不具有统计学意义;综合治疗组各时间点VAS评分均低于药物及针刀治疗组,综合治疗组肩关节功能评分在治疗后1个月和2个月高于药物及针刀治疗组,差异具有统计学意义(p<0.001)。3组的不良反应发生率,差异不具有统计学意义(p>0.05)。综上所述,针刀治疗联合曲安奈德、正清风痛宁、利多卡因及臭氧在关节腔及关节周围注射治疗肩周炎安全有效,值得在临床中推广应用。 相似文献
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Kamichika Hayashi Takeshi Onda Hirona Honda Natsuo Ozawa Hitoshi Ohata Nobuo Takano Takahiko Shibahara 《Biochemistry and Biophysics Reports》2019
No effective, reliable treatment for stomatitis associated with cancer therapy has been established. This study focused on the its effectiveness of ozone nano-bubble water (ONBW) for the treatment of chemotherapy-induced stomatitis. Oral mucositis was induced in 14-week-old male Sprague-Dawley rats (N = 21). The animals were randomly divided into 3 groups: 7 without treatment (control); 7 treated with physiological salt solution (saline); and 7 treated with ONBW. Animals were weighed on Days 7, 9, 11, and 16. Stomatitis grade evaluation and bacterial count measurements were performed before rinsing in all animals 3, 5, and 10 days after acetic acid irritation (Days 9, 11, and 17 respectively). Weight loss after stomatitis creation was observed in all groups, with significant differences between the control and ONBW groups and between the saline and ONBW groups on Day 16. The stomatitis grade did not worsen during the experimental period in any group, with the lowest grades in the ONBW group on Days 11 and 16. Significant differences were identified between the control and ONBW groups and between the saline and ONBW groups on Days 11 and 16. Oral bacterial counts tended to decrease over time in all three groups, with the greatest decrease in the ONBW group, followed by the saline group. The decrease in the bacterial count was steepest in the ONBW group. Rinsing out the oral cavity with ONBW decreased bacterial counts and encouraged the healing of oral chemotherapy-induced stomatitis. ONBW may be an effective treatment for chemotherapy-induced stomatitis. 相似文献
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Tropospheric ozone concentrations (O3) are continuously increasing with harmful effects on vegetation. Ozone uptake triggers oxidative stress that may promote adverse changes in various plant physiological processes. The aim of this study was to evaluate the relationship between meteorological conditions and O3 exposure in foliar injuries, gas exchanges and antioxidant enzyme activity in Psidium guajava Paluma. Saplings of Paluma were exposed in a site contaminated by O3. Foliar injuries, gas exchanges, and the activity of superoxide dismutase (SOD), ascorbate peroxidase (APX) and glutathione reductase (GR) were evaluated weekly. Results were analyzed by multivariate analysis. The O3 exposure reduced carbon assimilation and induced the onset of foliar injuries. The enzymatic activities were more related to meteorological conditions than to O3 exposure, indicating that these enzymes are not this species’ first line of defense. However, our finding indicates that Paluma may be considered a response indicator, given its presentation of foliar injuries even at low O3 concentrations. 相似文献
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To investigate the possible interactive effects of elevated atmospheric ozone (O3) concentrations and periodic drought stress on physiology of Shantung maple (Acer truncatum Bung), an experiment was conducted from the growth season of 2012 to 2013 with open-top chambers (OTCs) in Changping district, a suburb of Beijing, China. Four treatments were administered with three replications in twelve OTCs which were NN (well watered + ambient air), NO (well watered + add 100 nl l? 1 O3 above ambient air), DN (drought stress + ambient air) and DO (drought stress + add 100 nl l? 1 O3 above ambient air). Leaf area (LA), leaf mass per area (LMA), individual leaf weight (ILW), carbon(C), nitrogen (N) and sulfur (S) contents in early and late leaves were measured at the end of the second year. The results showed: (1) Both elevated O3 concentration and drought treatments significantly reduced early leaf LMA, LA, ILW, leaf N and S contents, with a reduction of 28.7, 45.7, 61.3, 39.6, 16.1% by O3 stress and 12.5, 46.8, 53.5, 15.45 and 22% by drought stress, respectively, while only LMA of late leaf was reduced 12.1% by O3 treatments and LA and ILW were significantly reduced 23.3% and 30% by drought treatments. (2) Significant interactions of elevated atmospheric O3 concentration and mild drought were detected on LMA, LA, ILW, N and C contents in early leaves and LMA in late leaves. Except for LA, the decreases under interactive treatments were all less than independent O3 effects. In conclusion, late leaf had less responses to elevated O3 and drought stresses than early leaves which need to be considered separately. The interactive effects suggested drought had antagonistic effects with O3 on growth indicators except for LA, indicating drought could mitigate the adverse efforts from O3 effects. 相似文献
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K. Ryu M. Watanabe H. Shibata K. Takagi M. Nomura Takayoshi Koike 《Landscape and Ecological Engineering》2009,5(2):99-106
For sustainable use and suitable management of larch plantations, we must clarify the ecophysiological responses of larch
species to environmental changes. The physical environment has been changing dramatically, e.g., increase in atmospheric CO2 concentration ([CO2]), nitrogen (N) deposition, and atmospheric ozone concentration ([O3]), and these changes may negatively affect growth of larch species. This review summarizes the previous experimental studies
on the ecophysiological responses of larch species to elevated [CO2], soil acidification, elevated [O3], and N load. Based on the advanced studies, although elevated [CO2] will stimulate the productivity of larch, increase of [O3] and severe soil acidification will reduce it. Increase of N deposition, at least, will not negatively affect larch productivity.
Finally, we propose the future direction for investigation to understand the mechanism of the responses of larch species and
to predict the associated risk. 相似文献
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Life cycle assessment of Australian automotive door skins 总被引:1,自引:0,他引:1
Prateek Puri Paul Compston Victor Pantano 《The International Journal of Life Cycle Assessment》2009,14(5):420-428
Background, aim, and scope Policy initiatives, such as the EU End of Life Vehicle (ELV) Directive for only 5% landfilling by 2015, are increasing the
pressure for higher material recyclability rates. This is stimulating research into material alternatives and end-of-life
strategies for automotive components. This study presents a Life Cycle Assessment (LCA) on an Australian automotive component,
namely an exterior door skin. The functional unit for this study is one door skin set (4 exterior skins). The material alternatives
are steel, which is currently used by Australian manufacturers, aluminium and glass-fiber reinforced polypropylene composite.
Only the inputs and outputs relative to the door skin production, use and end-of-life phases were considered within the system
boundary. Landfill, energy recovery and mechanical recycling were the end-of-life phases considered. The aim of the study
is to highlight the most environmentally attractive material and end-of-life option.
Methods The LCA was performed according to the ISO 14040 standard series. All information considered in this study (use of fossil
and non fossil based energy resources, water, chemicals etc.) were taken up in in-depth data. The data for the production,
use and end-of-life phases of the door skin set was based upon softwares such as SimaPro and GEMIS which helped in the development
of the inventory for the different end-of-life scenarios. In other cases, the inventory was developed using derivations obtained
from published journals. Some data was obtained from GM-Holden and the Co-operative research Centre for Advanced Automotive
Technology (AutoCRC), in Australia. In cases where data from the Australian economy was unavailable, such as the data relating
to energy recovery methods, a generic data set based on European recycling companies was employed. The characterization factors
used for normalization of data were taken from (Saling et. al. Int J Life Cycle Assess 7(4):203–218 2002) which detailed the method of carrying out an LCA.
Results The production phase results in maximum raw material consumption for all materials, and it is higher for metals than for the
composite. Energy consumption is greatest in the use phase, with maximum consumption for steel. Aluminium consumes most energy
in the production phase. Global Warming Potential (GWP) also follows a trend similar to that of energy consumption. Photo
Oxidants Creation Potential (POCP) is the highest for the landfill scenario for the composite, followed by steel and aluminium.
Acidification Potential (AP) is the highest for all the end-of-life scenarios of the composite. Ozone Depletion Potential
(ODP) is the highest for the metals. The net water emissions are also higher for composite in comparison to metals despite
high pollution in the production phases of metallic door skins. Solid wastes are higher for the metallic door skins.
Discussion The composite door skin has the lowest energy consumption in the production phase, due to the low energy requirements during
the manufacturing of E-glass and its fusion with polypropylene to form sheet molding compounds. In general, the air emissions
during the use phase are strongly dependent on the mass of the skins, with higher emissions for the metals than for the composite.
Material recovery through recycling is the highest in metals due to efficient separation techniques, while mechanical recycling
is the most efficient for the composite. The heavy steel skins produce the maximum solid wastes primarily due to higher fuel
consumption. Water pollution reduction benefit is highest in case of metals, again due to the high efficiency of magnetic
separation technique in the case of steel and eddy current separation technique in the case of aluminium. Material recovery
in these metals reduces the amount of water needed to produce a new door skin set (water employed mainly in the ingot casting
stage). Moreover, the use of heavy metals, inorganic salts and other chemicals is minimized by efficient material recovery.
Conclusions The use of the studied type of steel for the door skins is a poor environmental option in every impact category. Aluminium
and composite materials should be considered to develop a more sustainable and energy efficient automobile. In particular,
this LCA study shows that glass-fiber composite skins with mechanical recycling or energy recovery method could be environmentally
desirable, compared to aluminium and steel skins. However, the current limit on the efficiency of recycling is the prime barrier
to increasing the sustainability of composite skins.
Recommendations and perspectives The study is successful in developing a detailed LCA for the three different types of door skin materials and their respective
recycling or end-of-life scenarios. The results obtained could be used for future work on an eco-efficiency portfolio for
the entire car. However, there is a need for a detailed assessment of toxicity and risk potentials arising from each of the
four different types of door skin sets. This will require greater communication between academia and the automotive industry
to improve the quality of the LCA data. Sensitivity analysis needs to be performed such as the assessment of the impact of
varying substitution factors on the life cycle of a door skin. Incorporation of door skin sets made of new biomaterials need
to be accounted for as another functional unit in future LCA studies.
Discussion contributions to this article from the readership would the highly welcome. The authors 相似文献
9.
O3浓度升高对植物活性氧代谢系统影响的研究进展 总被引:1,自引:0,他引:1
为了揭示臭氧(O3)浓度升高对植物活性氧代谢系统的影响机理,从代谢生理角度,总结了近年来国内外关于臭氧浓度升高对植物活性氧自由基代谢速率、细胞膜脂过氧化程度、抗氧化系统及生物量和产量影响的研究进展,同时,就臭氧浓度升高与二氧化碳浓度升高的复合作用对植物活性氧代谢系统的影响,及阐明二者相互作用对植物抗氧化系统影响机理的研究进行了综述。在此基础上指出在未来研究中,要在分子水平上进一步深入研究植物活性氧代谢系统对高浓度臭氧、二氧化碳复合作用的响应机理,并应加强高浓度二氧化碳对臭氧胁迫下植物抗氧化系统影响的研究,为解决如何减轻臭氧浓度升高对植物造成的氧化伤害提供基础理论依据。 相似文献
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