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1.
《Saudi Journal of Biological Sciences》2017,24(8):1879-1883
ObjectiveTo study the early predictive value of cord blood bilirubin and dynamic monitoring of transcutaneous bilirubin for hyperbilirubinemia of newborns.Methods389 newborns delivered from June 2014 to December 2015 were enrolled as the research subjects; detailed records were made about the general data of newborns and mothers, and after cord blood bilirubin being graded, the incidence of hyperbilirubinemia was counted, and the prediction efficiency of cord blood bilirubin was analyzed by receiver operator characteristic (ROC) curve. At the same time, the transcutaneous bilirubin was detected continuously when the neonate was born and 24 h, 48 h and 72 h after birth, and the relativity between transcutaneous bilirubin at 72 h and serum bilirubin was analyzed.ResultsNo significant difference was found in the hyperbilirubinemia group and the non-hyperbilirubinemia group concerning general data of the newborns and their mothers. With the concentration of cord blood bilirubin increased, the incidence of hyperbilirubinemia also increased; separate prediction of hyperbilirubinemia by cord blood bilirubin showed a sensitivity and specificity of 71.4% and 65.6% respectively, and they need further dynamic monitoring. The daily mean of transcutaneous bilirubin in hyperbilirubinemia group was significantly higher than that in non-hyperbilirubinemia group at 24 h, 48 h and 72 h, and the measurement value of transcutaneous bilirubin at 72 h had a high correlation with serum bilirubin. When transcutaneous bilirubin value is higher than 18, the incidence of hyperbilirubinemia should be considered.ConclusionsThe increase of cord blood bilirubin effectively predict the occurrence of neonatal hyperbilirubinemia. There is a good correlation between levels of transcutaneous bilirubin and serum bilirubin. Moreover, combined detection of transcutaneous bilirubin and cord blood bilirubin can significantly improve the prediction accuracy of hyperbilirubinemia. 相似文献
2.
Kenji Tsuji Shinji KitamuraHirofumi Makino 《Biochemical and biophysical research communications》2014
The kidneys are exposed to hypoxic conditions during development. Hypoxia-inducible factor (HIF), an important mediator of the response to hypoxia, is believed to have an important role in development. However, the relationship between HIF and branching morphogenesis has not been elucidated clearly. 相似文献
3.
4.
The laminated structure of the optic tectum is formed by radial and tangential cell migration during development. Studies of developing chick optic tectum have revealed two streams of tangential cell migration in the middle and superficial layers, which have distinctive origins, migratory paths, modes of migration, and destinations. We will review the process of the two types of tangential migrations, in order to elucidate their roles in the formation of the optic tectum layers. 相似文献
5.
Understanding the state of forest resource utilization in China and correctly evaluating the role and function of forest resources in national economic development are essential for realizing balanced development of forests, the environment, and the economy. This is especially true given the present situation of increasingly scarce forest resources. Using data from Chinese forest industry statistical yearbooks, forestry development reports, and other documents, this paper examines the current state of forest resource utilization in China from the angle of combining quantities and values based on input–output tables. We show that demand for and input use of forest resources varies greatly across industrial sectors; the paper products and furniture manufacturing industries have the greatest direct consumption coefficient for timber use. When considering direct and indirect demand, it is clear that forest resources restrict different industrial sectors in diverse ways. These results provide an important set of reference values regarding the utilization of forest resources and coordinated industrial development in China. 相似文献
6.
Maria Weinert Tharakeswari Selvakumar Travis S. Tierney Kambiz N. Alavian 《Journal of visualized experiments : JoVE》2015,(96)
Degeneration of mesencephalic dopaminergic (mesDA) neurons is the pathological hallmark of Parkinson’s diseae. Study of the biological processes involved in physiological functions and vulnerability and death of these neurons is imparative to understanding the underlying causes and unraveling the cure for this common neurodegenerative disorder. Primary cultures of mesDA neurons provide a tool for investigation of the molecular, biochemical and electrophysiological properties, in order to understand the development, long-term survival and degeneration of these neurons during the course of disease. Here we present a detailed method for the isolation, culturing and maintenance of midbrain dopaminergic neurons from E12.5 mouse (or E14.5 rat) embryos. Optimized cell culture conditions in this protocol result in presence of axonal and dendritic projections, synaptic connections and other neuronal morphological properties, which make the cultures suitable for study of the physiological, cell biological and molecular characteristics of this neuronal population. 相似文献
7.
V.N. Pavlenko 《Journal of Russian & East European Psychology》2016,53(4):15-27
The article examines the problem of the relationship between universal and specific forms of cultural–historical development of mental processes. From different methodological approaches, the author prefers an activity approach which emphasizes genetic primacy of external practical activity. This approach allows, according to the author, universality of internalization and at the same time ethnic uniqueness of mental processes. The article clarifies the problem of internalization through two practical examples: 1) the development of mental counting actions and 2) the process of human goal setting. 相似文献
8.
The regional level has been recognized as a good scale for implementing actions towards sustainable development (SD). An important pathway to improve regional sustainability is to locally carry out long-term ecological planning. In order to reduce environmental impacts from fast economic growth, several eastern provinces of China began Ecological Province Construction (EPC) at the end of 1990s. This paper presented a case for analyzing the progress of EPC in China via both qualitative and quantitative methods. We studied Shandong Eco-province Construction (SEPC) and evaluated its outcomes with its pre-set indicators in 2003–2010. A further evaluation with eco-efficiency and de-linking indices was conducted. The results indicated the pre-set indicators could not effectively reflect of the ecological province construction. It was recommended to introduce an evaluated framework combined with eco-efficiency and de-linking indices to indicate ecological planning at the regional scale. 相似文献
9.
《Geobios》2014,47(5):305-313
An increasingly important source of annually resolved palaeoenvironmental proxy data originates from cross-dated incremental chronologies summarizing the shell growth of several individuals. Here, we have analysed annual increment variations in a collection of radiocarbon-dated shells of ocean quahog (Arctica islandica) from early Holocene prodelta deposits in north Norway. Radiocarbon dating of the shell material showed that the increments were formed contemporaneously during Preboreal times. The biologically youngest shell contains 35 annual increments, whereas the oldest shell shows 169 increments. Time-series of annual increments demonstrated clear age trends with the widest increments during the very early years of bivalve life, followed by a notable decline in increment widths as the bivalves aged. Subsequent to removing these biological trends from the series, a sclerochronological cross-dating was carried out and resolved the temporal alignments of the shell growth increment records relative to each other. The resulting shell growth increment chronology evidences vigorous growth variations. Spectral analysis of the chronology revealed 3.7- and 4.3-year periodicities, indicative of Preboreal environmental oscillations. Periodicities of longer period were not detected. Our results prove the value of radiocarbon-dated shell assemblages to build “floating” geochronologies for periods and regions where dead shells from museum collections or seabed are not obtainable. Increasing constructions of such chronologies enhance the potential of sclerochronological cross-dating of annual shell growth increment chronologies to depict and detail annually-resolved climate variability not only for late Holocene, as previously illustrated, but also for early Holocene times, when large-scale oscillations punctuated the global climate dynamics. Development of longer chronologies with higher sample replication remains an attainable interdisciplinary target. 相似文献
10.
The expression of the genes for two types of myrosinase (EC 3.2.3.1), designated MA and MB, during embryo and seedling development was investigated in Sinapis alba L. by in-situ and RNA slot-blot analyses. The expression of MA and MB genes followed similar temporal profiles during embryogenesis, but MB mRNA was present in considerably higher amounts than MA mRNA. In the embryo, both MA and MB genes are activated in cotyledons and axis. The MB genes are preferentially expressed in the cotyledons whereas MA genes are preferentially expressed in the axis. In the developing seedling, MA mRNA was not present in the organs investigated. By contrast, MB mRNA was found in appreciable amounts in hypocotyls, cotyledons and developing leaves. The MB genes seem to be activated preferentially in tissues undergoing rapid cell division and — or cell expansion.Abbreviations DAP
days after pollination
- MA, MB
A type, B type myrosinases in Sinapis alba
Anna-Stina Höglund (Uppsala Genetic Center) is gratefully acknowledged for valuable discussion, Anders Gobl (Department of Immunology, Uppsala University) for kindly advice with the labeling of probes and Qingzhu Zhai (Department of Pharmaceutical Biosciences, Uppsala University) for help with seed harvest. This work was supported by grants from the Swedish Research Council for Forestry and Agriculture. 相似文献