恶性疟原虫抗原表位的亚单位疫苗与DNA疫苗的联合免疫

构建了含有恶性疟原虫抗原基因 ( AWTE)的真核表达质粒 p CMV- AWTE,以及能在大肠杆菌中得到分泌性表达的原核表达质粒 p MC0 5 ,表达的蛋白 AWTE保持了疟原虫抗原的抗原性。将 p CMV- AWTE以及 AWTE两者混合各 1 0μg鼻腔免疫小鼠 ,一次后诱导机体产生了较高水平的体液免疫及细胞免疫     

N-糖蛋白去糖基化酶（PNGase）的研究进展

N-糖蛋白去糖基化酶（PNGase）是一种广泛存在于真菌、植物、哺乳动物中的去糖基化酶，可以水解N-糖蛋白或 N-糖肽上天冬酰胺与寡糖链连接的化学键，并释放出完整的N-寡糖。PNGase在生物体内参与蛋白质降解、器官发育、个体生长等过程。人PNGase基因功能缺陷会导致先天性去糖基化障碍，小鼠PNGase缺陷会导致胚胎致死性，线虫PNGase缺陷使其寿命下降。本文对PNGase在不同物种的分布、蛋白质结构、酶学功能及生物学功能进行阐述，为PNGase的生理病理功能及致病机制的基础研究提供思路，为PNGase作为糖生物学工具酶或药物开发的创新应用研究奠定基础。     

大冢制药公司在美国建新所着手细胞表面糖链的研究

大塚制药公司在美国开设的第2个生物所已确定明年2—3月起正式发展工作,主要进行阐明利用单克隆抗体的细胞表面糖链结构等项研究。这个研究所与基因操作中心的大冢马里兰工程研究所一起,建成在美国的从事细胞工程和基因工程研究的基地。     

轮虫

轮虫中浮游动物中的一个重要成员，广泛分布于各类淡水水域中，是经济水生动物的开口铒料和优质食物。有纤毛的头冠，骨质化的口器和焰茎球的原肾管是轮虫主要形态结构特征。研究轮虫可深入了解无脊椎动物的系统发育，亦可促进它的开发、利用。     

深圳大学校园规划建设的革新精神与人文内涵

深圳大学校园建筑被誉为学院派跨世纪佳作，是富有创新精神的深大人集体智慧的结晶，和许多大学比，其建筑结构与布局表现了先锋性（新）和独创性（异）、“异”指摆脱了老旧大学的传统建筑套路，“新”则在于体现了改革开放的时代精神和超前意识，校园民人和环境的协调关系，努力创造具有亲和力的“场”，顺应经济化的未来趋势，突出科技的地位和发展智能的重要性，寄寓“天地人和”的理想，从而使校园整体建构具有恒久的人价值     

濒危植物永瓣藤叶片功能性状对环境因子的响应

植物叶片功能性状能够响应环境条件的变化，反应了植物对环境的适应策略。当前，针对藤本植物叶片功能性状地理格局及其环境驱动力的研究较少。以国家重点保护植物永瓣藤（Monimopetalum chinense）为研究对象，对其分布区内11个种群的15个叶片功能性状进行测量，并结合气候、土壤因子来解释叶性状变异。比较叶片性状在局域和区域尺度上的种内变异程度，利用多元逐步回归分析环境因子对叶性状的影响。结果表明，在局域尺度上，永瓣藤叶功能性状变异系数介于3.0%-22.5%，其中，叶面积变异程度最大，叶片碳含量变异最小。永瓣藤叶片形状随纬度上升而变得宽且圆。叶片磷含量相对较低，永瓣藤的生长可能受到了磷限制。土壤与气候因子是叶片性状的重要驱动因素，解释了25%-97%的叶片性状变异。在温度和水分充足的情况下，永瓣藤叶片趋向于的慢速生长的保守策略。总体来说，永瓣藤叶片功能性状通过一定的种内变异和性状组合，并与气候、土壤因子相互作用，适应当前的环境条件。     

精胺和亚精胺影响水稻种子萌发与温度的关系(简报)

在25℃下以0．01～1．0mmol·L-1精胺和0．01～0．1mmol·L-1亚精胺预处理水稻种子48h，可以提高16℃下萌发指数和活力指数，但对28℃下的种子萌发无影响。种子萌发时胚芽中α-淀粉酶活性和胚芽、胚根的呼吸速率的变化规律基本上与活力指数相似。     

Fractal root system of Melica przewalskyi along different aspect in degraded grassland

Aims Fractal root system is phenotypic plasticity result of plant root architecture to respond to environmental heterogeneity, may reflect the growth strategy of plants to adapt to environmental conditions. Our objective was to explore the relationship between root fractal dimension and fractal abundance of fractal root system of Melica przewalskyi population in response to aspect variation in the northwest of China. Methods The study site was located in a degraded alpine grassland on the northern slope in Qilian Mountains, Gansu Province, China. Survey and sampling were carried out at 40 plots which were set up along four slope aspects transects with 20 m distance between adjacent plots. Handheld GPS was used to determine the elevation, longitude and latitude of each plot. ArcGIS was used to set up digital elevation model (DEM). Community traits were investigated and six individuals roots of M. przewalskyi were collected randomly at each plot. The samples were cleaned and divided into different organs, then scanning the root with the Win-RHIZO for measurements of fractal dimension and fractal abundance in laboratory, and their biomass were then measured after being dried at 80 °C in an oven. Important findings With the slope aspect turned from north to east, west, and south, the density, height and soil moisture content of the plant community displayed a pattern of initial decline, the height, density, root fractal abundance of M. przewalskyi increased and the root fractal dimension decreased. The root fractal dimension was negatively associated with the fractal abundance in all aspects, but the relationship varied along the slope aspects gradient; there was a highly significant negative correlation (p < 0.01) between the root fractal dimension and fractal abundance at north slope and south slope aspect, whereas the correlation only reached a significant level (p < 0.05) at the east slope aspect and west slope aspect; indicating that there is a trade-off between the root fractal dimension and fractal abundance. In addition, when the slope aspect changed from north to east, west and south, the standardized major axis (SMA) slope of the regression equation in the scaling relationships between root fractal dimension and fractal abundance increased (p < 0.05), indicating that the roots of M. przewalskyi at the droughty southern slope have less branch and more sparse in the same soil volume of root exploitation and utilization. Consequently, the resource allocation pattern on reasonable trade-off between root fractal dimension and fractal abundance in different slope aspect of M. przewalskyi, reflects the relationship between the income and the cost of construction of plant root architecture.