Luminescence of the near‐ultraviolet blue‐emitting Ba9Al2Si6O24:Ce3+ phosphor

A near‐ultraviolet (NUV) blue‐emitting phosphor Ba₉Al₂Si₆O₂₄:Ce³⁺ (BAS:Ce³⁺) was synthesized using a high‐temperature solid‐state reaction. BAS:Ce³⁺ had an excitation band peak at about 328 nm and showed a blue emission band. The NUV‐blue emission band had a peak at about 386 nm with a band width of about 60 nm, attributed to the 5d–4f transition of Ce³⁺. Fluorescent decay showed an exponential model with a lifetime of 27.2 nsec. At 150°C, the luminescence intensity decreased to 68.7% compared with the intensity at room temperature.     

The effect of sulfur-containing nitrogen fertilizers on the elemental composition of celery (Apium graveolens) grown on a polluted marsh soil

Summary In order to investigate elemental composition of celery, and to quantify the influence of sulfur-containing N-fertilizers on the trace element uptake, a field trial with celery was carried out on marsh soil polluted with municipal wastes. The research yielded the following results:Compared to leaves at harvest time, bulbs showed significantly lower concentrations of Mo, S and Sb, but higher contents of B, Br and Cr and Cu. Since the acidifying effect of the fertilizers was suppressed by the free calcium carbonate in the soil, no significant changes in concentrations of cationic trace elements were detected in plants fertilized with ammonium sulfate compared to those which received urea or calcium ammonium nitrate. On the other hand, in these plants the conspicuous increase in total sulfur was accompanied by a significant decrease in concentrations of up to 30% for B, Br and Sb, 50% for As, 60% for Se and 80% for Mo.According to these results, in plant production on contaminated soils certain plant parts may be marketable due to their low tendency to accumulate toxic elements, and furthermore it may be feasible to reduce the contents of some of these elements in plants by the use of sulfur-containing fertilizers.     

不同超级杂交稻组合期剑叶14C-同化物的转运及分配与早衰关系的研究

选取具有不同早衰特性的超级杂交稻组合两优培九、Y两优1号和培两优E32为供试材料,借助14C同位素示踪技术对其不同生育期剑叶14C同化物分配及转化进行了研究。结果表明:随着生育期的推进,剑叶(源)同化物向穗中(库)的转运比例逐渐增加,在供试组合中以两优培九分配效率最高,Y两优1号次之,培两优E32最低;剑叶14C-同化物在供试组合中的转运能力也有类似的趋势,在3个超级杂交稻组合中,以两优培九"源、库、流"的协调性最好,Y两优1号次之,培两优E32最差。     

~(90)锶对鲫鱼胚胎发育的影响及鲫仔鱼对~(90)锶吸收积累的研究

在胚胎发育过程中,用不同比放射性的~(90)锶试液处理受精卵,各处理组都有畸形和死亡现象。畸形的高峰一般出现在囊胚期和晶体形成期,畸形的类型一般为脊椎弯曲、体短、胸腔和卵黄囊扩大,头和眼畸形。随后即出现死亡高峰。例如:游动期的死亡率分别是:21%(对照);36%(5×10~(-11)居里/升);40%(5×1-~(-10)居里/升);45%(5×10~(-9)居里/升)。鲫仔鱼对~(90)锶吸收积累的结果表明:鲫仔鱼体中比放射性大小与试液的比放射性大小成正比,并随试验吋间的延长,生物量的增加而增加,鲫仔鱼的积累系数则不依试液的比放射性大小和生物量的多少为转移。     

MicroPET观察姜黄素对9月龄AD小鼠脑葡萄糖代谢的影响

目的通过氟18-脱氧葡萄糖MicroPET(18F-FDG microPET)影像技术观察姜黄素对9月龄AD小鼠的脑葡萄糖代谢影响。方法随机挑选9月龄(3月龄小鼠,干预6个月)模型组、西药组和姜黄素大、中、小剂量组AD小鼠各3只,以及同月龄C57BL/6J正常对照组小鼠3只,通过吸入2%异氟烷麻醉后,每例弹丸式从尾静脉注射放射性示踪剂18F-FDG约14.8～16.5 MBq,摄取1 h后采集10 min MicroPET图像。计算每组小鼠每克脑组织(除小脑)18F-FDG的摄取率并比较分析其差异。结果姜黄素中剂量组小鼠和西药组小鼠每克脑组织18F-FDG的摄取率高于正常对照组和模型组。结论姜黄素治疗后,9月龄AD模型小鼠脑18F-FDG的摄取有所改善,提示AD模型脑糖代谢所反映的脑功能得到改善,姜黄素发挥了神经保护作用。     

不同植物构成的人工湿地对生活污水中氮的去除效应

测定由不同植物构成的人工湿地的氨态氮、硝态氮和亚硝态氮含量,对比不同植物对生活污水中氮的去除效率.结果表明,与不种植物的人工湿地相比,由风车草[Cyperus alternifolius L. ssp. flabelliformis (Rottb.) Kiikenth.]、香根草[Vertiveria zizanioides (Linn.) Nash]、芦苇(Phragmitas communis Trin.)和美人蕉(Canna indica Linn.)构成的人工湿地对氨态氮去除率分别提高6%、8%、11%和14%;对硝态氮去除率分别提高5%、6%、13%和9%;对亚硝态氮去除率分别提高5%、7%、10%和7%,说明种植芦苇和美人蕉的人工湿地对生活污水中的氮具有较好的去除效果.     

The diagnostic efficacy of circulating miRNAs in monitoring the early development of colitis-induced colorectal cancer

Early detection of colorectal cancer and monitoring the progress in colon carcinogenesis stages is essential to reduce mortality. Therefore, there is continuous search for noninvasive biomarkers with high stability and good sensitivity and specificity. miRNAs have attracted attention as promising biomarkers as they are stably expressed in circulation. The aim of our study is to evaluate the aberrant expression of circulating miRNAs during the stepwise progress of colitis-associated colon cancer. This was accomplished through assessing the expression levels of five miRNAs (miR-141, miR-15b, miR-17-3p, miR-21, and miR-29a) in serum and their corresponding tissue samples through the different cycles of colorectal carcinogenesis cascade using the azoxymethane/dextran sulfate sodium murine model. We also compared the diagnostic performance of these selected miRNAs with the conventional tumor biomarkers CEA and CA 19-9. The results of our study revealed that the expression levels of those miRNAs were dynamically changing in accordance with the tumor development state. Moreover, their aberrant expression in serum was statistically correlated with that in tissue. Our data also revealed that serum miR-15b, miR-21, and miR-29a showed the best performance in terms of diagnostic power. Our findings highlight the efficiency of these circulating miRNAs not only for early diagnostics purposes, but also for monitoring progress in the colorectal carcinogenesis process, and therefore encouraging integrating these noninvasive biomarkers into the clinical diagnostic settings beside the traditional diagnostic markers for accurate screening of the early progress of colon carcinogenesis.     

妊娠期糖尿病肾功能损害患者血清miR-135b、miR-141表达水平的变化及意义

摘要 目的：探讨血清miR-135b、miR-141在妊娠期糖尿病（GDM）肾功能损害患者中的表达及作用。方法：选取2019年3月至2020年12月在我院就诊的GDM患者200例作为GDM组,根据有无肾功能损伤分为GDM组（n=83）和GDM肾功能损伤组（n=117）,再将肾病患者根据尿白蛋白/肌酐比值（UACR）分为轻度65例、中度37例和重度15例。另选择同期在我院产检的正常妊娠孕妇100例为对照组。测定孕妇血清中miR-135b、miR-141水平及肾功能指标,Pearson法分析GDM肾病患者血清miR-135b、miR-141与肾功能指标的相关性。采用非条件Logistic 多元回归分析GDM肾功能损伤的危险因素。结果：GDM肾功能损伤组孕妇血清miR-135b、miR-141表达水平高于GDM组和对照组,GDM组明显高于对照组（P<0.05）。GDM肾功能损伤组肌酐（Scr）、β₂-微球蛋白（β₂-MG）、UCAR表达水平高于GDM组和对照组,肾小球滤过率（eGFR）低于GDM组和对照组,差异有统计学意义（P<0.05）。血清miR-135b、miR-141表达水平与Scr、β₂-MG、UCAR呈正相关（P<0.05）,与eGFR呈负相关（P<0.05）。肾功能重度损伤孕妇血清miR-135b、miR-141表达水平明显高于肾功能中度损伤和轻度损伤孕妇,且肾功能中度损伤明显高于轻度损伤（P<0.05）。非条件 Logistic 多元回归分析结果显示,miR-135b、miR-141表达水平是孕妇GDM发生的危险因素（P<0.05）。结论：GDM肾功能损伤患者血清miR-135b、miR-141水平异常升高,且随着肾功能损害的加重其水平逐渐增加,可为GDM肾功能损伤的预测和治疗提供一定参考。