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61.
Brent M. Graves 《Evolutionary ecology》2007,21(5):663-668
Although the basic theories concerning evolution of senescence have been generally accepted for a half-century, interpretation
of this paradigm has been constrained by an over-reliance on mortality as both the cause and the measure of senescence. Consideration
of both survival and fecundity as components of reproductive value, and integration of sexual selection theory with senescence
theory allows reconciliation of long-standing, as well as recent, discrepancies between data and theory. This approach demonstrates
that sexual selection on males in polygynous mating systems can have significant effects on the evolution of senescence that
could overshadow the selection effects of mortality rates among such animals. 相似文献
62.
This study determined the effects of contact with DEET on guinea pig skin on mortality, probing time, blood feeding rate, engorgement time, and fecundity responses in female Anopheles quadrimaculatus Say. Exposure, in this manner, to 10% DEET (in ethanol) for 5 min, resulted in 98% mortality in mosquitoes after 24h. The median probing time (PT(50)) required by females, when exposed to 0.1%, 1.0%, and 10% DEET, was significantly (P<0.0001) longer (12.5, 12.1, and 19.1s, respectively) than the 6.8s required by females to probe ethanol-treated skin (control). Similarly, mean blood feeding rates in populations of females exposed to 1.0% DEET for < or = 5 min (14.4%) was 6x lower (P<0.001) (85.5%) than in females exposed to ethanol-treated skin, whereas the mean engorgement time on skin treated with 1.0% DEET (66.3s) was significantly shorter (P<0.0001) than for females feeding on the control guinea pigs (105.9s). The mean number of mature o?cytes per female (fecundity) in treatment (1.0% DEET) and control mosquitoes was not significantly different. The responses to DEET observed in this study suggest that repeated exposure of female A. quadrimaculatus populations to this repellent, in laboratory bioassays, could result in confounding of toxicant and repellent effects and inaccurate estimates of DEET repellency. 相似文献
63.
Reading CJ 《Oecologia》2007,151(1):125-131
There is general consensus that climate change has contributed to the observed decline, and extinction, of many amphibian
species throughout the world. However, the mechanisms of its effects remain unclear. A laboratory study in 1980–1981 in which
temperate zone amphibians that were prevented from hibernating had decreased growth rates, matured at a smaller size and had
increased mortality compared with those that hibernated suggested one possible mechanism. I used data from a field study of
common toads (Bufo bufo) in the UK, between 1983 and 2005, to determine whether this also occurs in the field. The results demonstrated two pathways
by which global warming may cause amphibian declines. First, there was a clear relationship between a decline in the body
condition of female common toads and the occurrence of warmer than average years since 1983. This was paralleled by a decline
in their annual survival rates with the relationship between these two declines being highly correlated. Second, there was
a significant relationship between the occurrence of mild winters and a reduction in female body size, resulting in fewer
eggs being laid annually. Climate warming can, therefore, act on wild temperate zone amphibians by deleteriously affecting
their physiology, during and after hibernation, causing increased female mortality rates and decreased fecundity in survivors. 相似文献
64.
The influence of depth,site exposure and season on the intensity of iceberg scouring in nearshore Antarctic waters 总被引:5,自引:3,他引:2
Ice scour disturbance has a significant effect on the physical and biological characteristics of polar benthos. A series of
grids, each consisting of 25 markers, were deployed along depth transects and replicated at two contrasting study sites at
Adelaide Island, West Antarctic Peninsula. Markers were surveyed and replaced every 3 months for 2 years in order to assess
the frequency and intensity of iceberg impacts. Depth, site, season and year were all highly significant factors influencing
ice scouring frequency. We observed a high variation in the duration of winter fast ice between sites and years, which had
a marked effect on ice scouring frequency. The ecological effects of the disturbance regime are likely to include depth zonation
of benthic assemblages, patchiness of communities at varying stages of recovery and the near denudation of sessile fauna in
the shallow subtidal.
相似文献
Dan A. SmaleEmail: |
65.
Background
Implantable Cardioverter-defibrillators (ICD) reduce mortality in survivors of cardiac arrest (CA). We investigated the predictors of mortality after ICD implantation in survivors of CA.Methods
Retrospective review of clinical records and social security death index of all patients who received an ICD in a preexisting database of survivors of CA at the University of Pittsburgh Medical Center was performed. Multivariate analyses using the Cox proportional hazard model were performed with backward elimination to identify independent predictors of the time to death, and Kaplan-Meier curves were plotted.Results
Eighty patients (64 men) with a mean age of 64.4±12.5 years were followed for 4.7±2.3 years after ICD implantation. Survival rates were 93.8%, 65% and 50% at 1, 5, and 10 years, respectively. Independent predictors of time to death were determined to include age (hazard ratio (HR) = 1.91 per 10-year increase, p = 0.003), serum creatinine ≥ 1.3 mg/dL (HR = 2.56, p = 0.004), and QRS width >120 ms (HR = 5.14, p = 0.012).Conclusions
In this sample of ICD recipients secondary to CA, older age, elevated serum creatinine, and wider QRS duration were independent predictors of mortality. The presence of more than one risk factor in the same patient was associated with higher mortality rates. Whether interventions such as biventricular pacing can offset this increase risk of death warrants further investigation. 相似文献66.
Age of tooth emergence is a useful measure of the pace of life for primate species, both living and extinct. A recent study combining wild chimpanzees of the Taï Forest, Gombe, and Bossou by Zihlman et al. (2004) suggested that wild chimpanzees erupt teeth much later than captives, bringing into question both comparisons within the hominin fossil record and assessment of chimpanzees. Here, we assess the magnitude of the “wild effect” (the mean difference between captive and wild samples expressed in standard deviation units) in these chimpanzees. Tooth emergence in these wild individuals is late, although at a more moderate level than previously recorded, with a mean delay conservatively estimated at about 1 SD compared to the captive distributions. The effect rises to 1.3 SD if we relax criteria for age estimates. We estimate that the mandibular M1 of these wild chimpanzees emerges at about 3 2/3-3 ¾ years of age. An important point, often ignored, is that these chimpanzees are largely dead of natural causes, merging the effect of living wild with the effect of early death. Evidence of mortality selection includes, specifically: younger deaths appear to have been more delayed than the older in tooth emergence, more often showed evidence of disease or debilitation, and revealed a higher occurrence of dental anomalies. Notably, delay in tooth emergence for live-captured wild baboons appears lower in magnitude (ca. 0.5 SD) and differs in pattern. Definitive ages of tooth emergence times in living wild chimpanzees must be established from the study of living animals. The fossil record, of course, consists of many dead juveniles; the present study has implications for how we evaluate them. 相似文献
67.
Garamszegi LZ 《International journal for parasitology》2011,41(2):205-212
Plasmodium parasites, the causative agents of malaria, are generally considered as harmful parasites, but many of them cause mild symptoms. Little is known about the evolutionary history and phylogenetic constraints that generate this interspecific variation in virulence due to uncertainties about the phylogenetic associations of parasites. Here, to account for such phylogenetic uncertainty, phylogenetic methods based on Bayesian statistics were followed in combination with sequence data from five genes to estimate the ancestral state of virulence in primate Plasmodium parasites. When recent parasites were categorised according to the damage caused to the host, Bayesian estimates of ancestral states indicated that the acquisition of a harmful host exploitation strategy is more likely to be a recent evolutionary event than a result of an ancient change in a character state altering virulence. On the contrary, there was more evidence for moderate host exploitation having a deep origin along the phylogenetic tree. Moreover, the evolution of host severity is determined by the phylogenetic relationships of parasites, as severity gains did not appear randomly on the evolutionary tree. Such phylogenetic constraints can be mediated by the acquisition of virulence genes. As the impact of a parasite on a host is the result of both the parasite’s investment in reproduction and host sensitivity, virulence was also estimated by calculating peak parasitemia after eliminating host effects. A directional random-walk evolutionary model showed that the ancestral primate malarias reproduced at very low parasitemia in their hosts. Consequently, the extreme variation in the outcome of malaria infection in different host species can be better understood in light of the phylogeny of parasites. 相似文献
68.
M. Kamrul Islam Ulf-G. Gerdtham Bo Gullberg Martin Lindstrm Juan Merlo 《Economics & Human Biology》2008,6(1):19-42
We conceptualize social capital as an aggregate factor affecting health production and analyze the effect of community social capital (CSC) externalities on individual mortality risk in Sweden. The study was based on a random sample from the adult Swedish population of approximately 95,000 individuals who were followed up for 4-21 years. Two municipality-level variable--registered election participation rate and registered crime rate--were used to be a proxy for CSC. The impact of CSC on mortality was estimated with an extended Cox model, controlling for the initial health status and a number of individual characteristics. The results indicate that both proxies of CSC were associated with individual risk from all-cause mortality for males older than 65+ (p=0.013 and p=0.008) but not for females. A higher election participation rate negatively and significantly associated with the mortality risk from cancer for males (p=0.007), and may also have exerted protective associations for cardiovascular mortality (p=0.134) and deaths due to "suicide" (p=0.186) or "other external causes" (p=0.055). Similar associations were observed for the crime rate variable. The findings were robust to alternative specifications examined in the sensitivity analysis. 相似文献
69.
Summary . A distributed lag model (DLagM) is a regression model that includes lagged exposure variables as covariates; its corresponding distributed lag (DL) function describes the relationship between the lag and the coefficient of the lagged exposure variable. DLagMs have recently been used in environmental epidemiology for quantifying the cumulative effects of weather and air pollution on mortality and morbidity. Standard methods for formulating DLagMs include unconstrained, polynomial, and penalized spline DLagMs. These methods may fail to take full advantage of prior information about the shape of the DL function for environmental exposures, or for any other exposure with effects that are believed to smoothly approach zero as lag increases, and are therefore at risk of producing suboptimal estimates. In this article, we propose a Bayesian DLagM (BDLagM) that incorporates prior knowledge about the shape of the DL function and also allows the degree of smoothness of the DL function to be estimated from the data. We apply our BDLagM to its motivating data from the National Morbidity, Mortality, and Air Pollution Study to estimate the short-term health effects of particulate matter air pollution on mortality from 1987 to 2000 for Chicago, Illinois. In a simulation study, we compare our Bayesian approach with alternative methods that use unconstrained, polynomial, and penalized spline DLagMs. We also illustrate the connection between BDLagMs and penalized spline DLagMs. Software for fitting BDLagM models and the data used in this article are available online. 相似文献
70.
After considering the observed long-term trends in average monthly temperatures distribution in Moscow, the authors evaluated
how acute mortality responded to changes in daily average, minimum and maximum temperatures throughout the year, and identified
vulnerable population groups, by age and causes of death. A plot of the basic mortality–temperature relationship indicated
that this relationship was V-shaped with the minimum around 18°C. Each 1°C increment of average daily temperature above 18°C
resulted in an increase in deaths from all non-accidental causes by 2.8%, from coronary heart disease by 2.7%, from cerebrovascular
diseases by 4.7%, and from respiratory diseases by 8.7%, with a lag of 0 or 1 day. Each 1°C drop of average daily temperature
from +18°C to −10°C resulted in an increase in deaths from all non-accidental causes by 0.49%, from coronary heart disease
by 0.57%, from cerebrovascular diseases by 0.78%, and from respiratory diseases by 1.5%, with lags of maximum association
varying from 3 days for non-accidental mortality to 6 days for cerebrovascular mortality. In the age group 75+ years, corresponding
risks were consistently higher by 13–30%. The authors also estimated the increase in non-accidental deaths against the variation
of daily temperatures. For each 1°C increase of variation of temperature throughout the day, mortality increased by 0.3–1.9%,
depending on other assumptions of the model. 相似文献