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( Dept.of Math. Faculty of Science Mansoura Egypt Dept.of Math. Faculty of Education Kafr El-Sheikh Tanta University Egypt.) 《生物数学学报》1997,(3)
1IntreductionTheliteratUreonmulti-Criteriondecisionmaking(MCDM)problemshas~tremendouslyintherecentpast.TwomajorareashaveevolvedwhiChbothconcentrateondecisionmakingwithseveralcriteria:multiobjectivedecisionmaking(MODM)andmulti-attributedecisionmaking(MADM).TheformerconcentratesoncontinuousdecisionspaceandthelatterfocusesonproblemswithdiscreteSPace.FuzzysettheoryhascontributedtoMODMproblemsaswellastheMADMProblems.ThegeneralMODMproblemcanbedeft.edLllasfollows:Twostagescangenerallybe… 相似文献
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微藻生物技术是较新的生物技术领域之一。藻的生物技术本质上与农业相同,即利用光合成机制生产生物量,用作食物、饲料、化学药品和能源。 培养微藻作生物量的主要优点为: 1.藻是很有效的生物系统,是以太阳能通过光合成生产有机化合物的。 相似文献
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ZHU JINGDE 《Cell research》1995,(1)
INTanDUCTI0NMyeloidcelldifferentiati0n,inwhichmultip0tentialprogenitorcellsarec0nvertedint00neofthesixmaturedifferentiatedcells,i.e.,erythr0cytes,platelets(megakary-ocytes),macr0phages,neutr0phils,e0sinophilsandbas0phils,involvestemporalre-gulati0nofexpression0fanumberoflineage-anddifferentiationstage-specificgenes.Understandingthedevel0pmentalspecificationoflineageaJswellasmaturationstageassociatedpatterns0fgeneexpressioninmyel0idcelldifferentiationrequiresanin-sightintothecontrol0findivid… 相似文献
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研究江汉平原豆麦(大豆/小麦)和稻麦(水稻/小麦)轮作系统中冬小麦生长规律对氮肥运筹模式的响应,可为缩小两种轮作模式下的小麦产量差异提供理论依据。试验设置传统施肥(70%底肥,30%越冬期追肥)和优化施肥(1/3底肥,1/3越冬期追肥,1/3拔节期追肥)2个处理,并以不施氮处理为对照,分析了豆麦和稻麦轮作系统中冬小麦的生长规律、产量及产量构成因素、肥料利用率和施肥效益等。结果表明: 施氮和轮作模式均对小麦产量有显著影响,优化施肥产量显著高于传统施肥,两者产量差异在豆麦轮作系统下为920 kg·hm-2,在稻麦轮作系统下为2195 kg·hm-2。相同轮作模式下,传统施肥冬季、春季群体茎蘖数高于优化施肥,而优化施肥在整个生育期干物质总积累量较传统施肥高5%~31%(豆麦)和14%~28%(稻麦)。传统施肥下豆茬小麦产量较高的原因是穗数、成穗率、群体干物质积累量等均高于稻茬小麦;优化施肥下稻茬小麦产量较豆茬小麦增加幅度更大,表明优化氮肥模式可缩小豆麦与稻麦轮作中小麦的产量差异。两种轮作模式中小麦花后粒重分别呈现“慢-快-中”(豆麦)和“中-快-慢”(稻麦)的增加趋势;氮肥农学效率、小麦季纯收益等指标均以稻麦轮作优化施肥处理最高。综上,在江汉平原地区,稻麦轮作优化施肥处理下小麦群体结构合理,干物质积累量较高,产量和施肥效益增加显著,是江汉平原地区兼顾产量与施肥效益的最佳模式。 相似文献
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自噬是一个通过降解细胞组分如细胞器和蛋白质等以维持细胞存活和功能的重要的溶酶体途径。肝脏作为新陈代谢的中枢器官,肝脏高度依赖于自噬以发挥正常功能并防止疾病发展。肝细胞自噬的改变参与肝损伤,脂肪肝等肝病的病理变化,以自噬为靶点寻求治疗各种肝病的方法已成为热点研究领域,但自噬在肝脏蛋白质和脂质代谢中的作用极其机制尚不清楚。本文对自噬在肝脏蛋白质和脂质代谢中的作用的最新进展进行综述。 相似文献
7.
Herman AE Tisch RM Patel SD Parry SL Olson J Noble JA Cope AP Cox B Congia M McDevitt HO 《Journal of immunology (Baltimore, Md. : 1950)》1999,163(11):6275-6282
Particular HLA class II allelic sequences are associated with susceptibility to type I diabetes. To understand the mechanism, knowledge of the molecular nature of the specific TCR/peptide/class II interactions involved in the disease process is required. To this end, we have introduced the diabetes-associated human class II HLA-DQ8 allele (DQA1*0301/DQB1*0302) as a transgene into mice and analyzed T cell responses restricted by this molecule to an important Ag in human diabetes, human glutamic acid decarboxylase 65. Hybridomas were used to determine the particular peptides from this Ag presented by HLA-DQ8 to T cells and to map the core minimal epitopes required for T cell stimulation. Analysis of these core epitopes reveals a motif and relevant features for peptides that are immunogenic to T cells when presented by HLA-DQ8. The major immunogenic epitopes of glutamic acid decarboxylase 65 do not contain a negatively charged residue that binds in the P9 pocket of the HLA-DQ8 molecule. PBMC from HLA-DQ8+ diabetic and nondiabetic individuals respond to these peptides, confirming that the mouse model is a useful tool to define epitopes of autoantigens that are processed by human APC and recognized by human T cells. 相似文献
8.
WEI MIN NI XIAO YA CHEN ZHI HONG XU HONG WEI XUE. * National Laboratory of Plant Molecular Genetics Institute of Plant Physiology Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Partner Group of Max-Pla 《Cell research》2002,(Z1)
Polar auxin transport plays a divergent role in plant growth and developmental processes including root and embryo development, vascular pattern formation and cell elongation. Recently isolated Arabidopsis pin gene family was believed to encode a component of auxin efflux carrier (G(?)lweiler et al, 1998). Based on the Arabidopsis pin1 sequence we have isolated a Brassica juncea cDNA (designated Bjpin1), which encoded a 70-kDa putative auxin efflux carrier. Deduced BjPIN1 shared 65% identities at protein level with AtPINl and was highly homologous to other putative PIN proteins of Arabidopsis (with highest homology to AtPIN3). Hydrophobic analysis showed similar structures between BjPINl and AtPIN proteins. Presence of 6 exons (varying in size between 65 bp and 1229 bp) and 5 introns (sizes between 89 bp and 463 bp) in the genomic fragment was revealed by comparing the genomic and cDNA sequences. Northern blot analysis indicated that Bjpin1 was expressed in most of the tissues tested, with a relatively h 相似文献
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