广西,贵州的Zellia及其地层分布

标本采自广西宜山、天等和贵州独山、紫云等地的早二叠世地层中。Ｚｅｌｌｉａ富集于层面,大多和Ｐｓｅｕｄｏｓｃｈｗａｇｅｒｉｎａ,Ｓｐｈａｅｒｏｓｃｈｗａｇｅｒｉｎａ,Ｒｏｂｕｓｔｏｓｃｈｗａｇｅｒｉｎａ共生,在确定石炭－二叠系界线时具有一定的地层意义。现对Ｚｅｌｌｉａ的属征加以阐述、讨论和归并,并对其地理地层分布作一简介。     

假希瓦格属(Pseudoschwagerina)和球希瓦格属(Sphaeroschwagerina)

Ｐｓｅｕｄｏｓｃｈｗａｇｅｒｉｎａ属的系统渊源、地质历程、分布范围均不同于Ｓｐｈａｅｒｏｓｃｈｗａｇｅｒｉｎａ属,二者在地理分布上亦具差异。以它们命名的生物地层延限带顶、底界均不等同。     

广西天等地区晚石炭世-早二叠世含䗴地层及化石带

简要地介绍了广西天等地区晚石炭世－早二叠世含Ｔｉｎｇ地层,对Ｔｉｎｇ类动物群进行了较详细的研究,自下而上建立了７个化石带,分别为：１．Ｍｏｎｔｉｐａｒｕｓ ｍｏｎｔｉｐａｒｕｓ带;２．Ｔｒｉｔｉｃｉｔｅｓ ｖａｒｉａｂｉｌｉｓ带;３．Ｐｓｅｕｄｏｓｃｈｗａｇｅｒｉｎａ ｂｅｅｄｅｉ带;４．Ｓｐｈａｅｒｏｓｃｈｗａｇｅｒｉｎａ ｓｐｈａｅｒｉｃａ带;５．Ｍｃｃｌｏｕｄｉａ ｏｖａｔａ带;６．Ｓｃｈｗ     

云南墨江下密地早二叠世常么期含 地层及 化石带

简要介绍云南墨江下密地早二叠世常么期含Ｔｉｎｇ地层,对其中Ｔｉｎｇ类动物群特征作了归纳,记述７属２９种,其中包括４新种。依据Ｔｉｎｇ类化石在该剖面中的垂直分布在常么组建立Ｅｏｐａｒａｆｕｓｕｌｉｎａ ｇｒａｃｉｌｉｓ－Ｅｏ．ｍｅｊｉａｎｇｅｎｓｉｓ带和Ｃｈａｌａｒｏｓｃｈｗａｇｅｒｉｎａ ｖｕｌｇａｒｉｓ－Ｃｈａｌａｒｏｓｃｈｗａｇｅｒｉｎａ ｐｓｅｕｄｏｖｕｌｇａｒｉｓ带。并与国内外相关地层进行     

假希瓦格Ting属（Pseudoschwagerina）和球希瓦格Ting属（Sphaer…

Ｐｓｅｕｄｏｓｃｈｗａｇｅｒｉｎａ属的系统渊源,地质历程,分布范围均不同于Ｓｐｈａｅｒｏｓｃｈｗａｇｅｒｉｎａ 属,二者在地理分布上亦具差异。以它们命名的生物地层限带顶,底界均不等同。     

桂西北早,中二叠世常么期和栖霞期Ting类动物群

桂西北早、中二叠世常么期和栖霞期Ｔｉｎｇ类十分丰富,自下而上可建立５带４亚带：１）Ｐａｍｉｒｉｎａ－Ｓｃｈｗａｇｅｒｉｎａ带（Ｐａｍｉｒｉｎａ ｐｕｌｉｃｈｒａｇ亚带;Ｓｃｈｗａｇｅｒｉｎａ ｃｕｓｈｍａｎｉ亚带）;２）Ｓｃｈｗａｇｅｒｉｎａ ｇｕｅｍｂｅｌｉ带;３）Ｃｈａｌａｒｏｓｃｈｗａｇｅｒｉｎａ－Ｒｏｂｕｓｔｏｓｃｈｗａｇｅｒｉｎａ带（Ｃｈａｌａｒｏｓｃｈｗａｇｅｒｉｎａ ｖｕｌｇａｒｉｓ     

桂西北早、中二叠世常么期和栖霞期类动物群

桂西北早、中二叠世常么期和栖霞期类十分丰富,自下而上可建立５带４亚带：１）ＰａｍｉｒｉｎａＳｃｈｗａｇｅｒｉｎａ带（Ｐａｍｉｒｉｎａｐｕｌｃｈｒａｇ亚带;Ｓｃｈｗａｇｅｒｉｎａｃｕｓｈｍａｎｉ亚带）;２）Ｓｃｈｗａｇｅｒｉｎａｇｕｅｍｂｅｌｉ带;３）ＣｈａｌａｒｏｓｃｈｗａｇｅｒｉｎａＲｏｂｕｓｔｏｓｃｈｗａｇｅｒｉｎａ带（Ｃｈａｌａｒｏｓｃｈｗａｇｅｒｉｎａｖｕｌｇａｒｉｓ亚带;Ｒｏｂｕｓｔｏｓｃｈｗａｇｅｒｉｎａｌｏｎｇｌｉｎｅｎｓｉｓ亚带）;４）Ｂｒｅｖａｘｉｎａｄｙｈｒｅｎｆｕｒｔｈｉ带;５）Ｍｉｓｅｌｉｎａｃｌａｕｄｉａｅ带。并对研究区类动物群的特征,岩相和沉积环境进行了探讨。     

福建漳平早二叠世Schwagerina cushmani筳类动物群

福建漳平早二叠世Ｓｃｈｗａｇｅｒｉｎａｃｕｓｈｍａｎｉ动物群的层位介于梁山组与含假希瓦格亚科分子的马平组之间。动物群分子以Ｓｃｈｗａｇｅｒｉｎａｃｕｓｈｍａｎｉ,Ｄａｒｖａｓｉｔｅｓｓｉｎｅｎｓｉｓ,Ｐｓｅｕｄｏｆｕｓｕｌｉｎａｇａｌｏｗａｙｉ为主,与湘东南的Ｓｃｈｗａｇｅｒｉｎａｃｕｓｈｍａｎｉ类群、江苏宁镇山区的Ｄａｒｖａｓｉｔｅｓｏｒｄｉｎａｔｕｓ类群相一致。     

两淮煤田太原组蜓类生态环境的初步研究

本文概括地介绍了两淮地区太原组的岩性特征。根据所含　类动物群的垂直分布情况,该区太原组可建立Ｓｐｈａｅｒｏｃｈｗａｇｅｒｉｎａ带（可细分为下部的Ｑｕａｓｉｆｕｓｕｌｉｎａｇｒａｃｉｌｉｓ－Ｂｏｕｌｔｏｎｉａｗｉｌｌｓｉ亚带和上部的Ｓｐｈａｅｒｏｓｃｈｗａｇｅｒｉｎａｓｕｂｒｏｔｕｎｄａ亚带）,其时代应属晚石炭世晚期。通过对太原组灰岩的沉积特征、　类分异度及其共生生物群保存情况等方面综合研究,较详细地讨论了海水盐度、温度、深度、浑浊度、水动力条件等生态因素对　类的限制作用。     

福建漳平早二叠世SchwagerinacushmaniTing类动物群

福建涧产早二叠世Ｓｈｗａｇｅｒｉｎａｃｕｓｈｍａｎｉ动物群的层位介于梁山组与含假瓦格Ｔｉｎｏｇ亚科分子的马平组之间。动物群分子以Ｓｈｗａｇｅｒｉｎｃｕｓｈｍａｎｉ,Ｄａｒｖａｓｉｔｅｓｓｉｎｅｎｓｉｓ,Ｐｓｅｕｄｏｆｕｓｕｌｉｎａｇａｌｌｏｗａｙｉ为主,与湘东南的ＳｃｈｗａｇｅｒｉｎａｃｕｓｈｍａｎｉＴｉｎｇ类群,江苏宁镇山区的ＤａｒｖａｓｉｔｅｓｏｒｄｉｎａｔｕｓＴｉｎｇ类群相一致。     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.