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本文对关于微波和移动电话辐射等高频电磁辐射对生殖系统的损伤的研究加以总结,系统研究高频辐射对生殖的影响. 相似文献
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电磁辐射对人类健康的影响 总被引:3,自引:0,他引:3
电磁波在推动社会发展的同时,也影响了我们的生活。阐述了电磁辐射污染对人类产生的主要危害、损伤机制以及应对措施,从而减少电磁辐射对人类健康产生的危害。 相似文献
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电磁辐射是一种复合电磁波,而人体生命活动包含一系列的生物电活动,这些生物电对环境的电磁波敏感,因此,电磁辐射可对人体造成危害.关于电磁辐射诱导的生物效应研究虽多,然而其具体机制尚不清楚.近年来,发现烟酰胺腺嘌呤二核苷酸磷酸氧化酶(NADPH氧化酶),又称呼吸爆发氧化酶(respiratory burst oxidase homologue,Rboh)在电磁辐射产生的生物学效应中扮演重要角色,电磁辐射可直接或间接活化NADPH氧化酶复合体,然后NADPH氧化酶可以将细胞内NADPH的电子转移而形成活性氧,或者通过一系列炎症因子和相关基质金属蛋白酶等参与炎症、防御以及组织修复等生命过程.本文对NADPH氧化酶在电磁生物学效应中的作用进行了综述. 相似文献
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电磁辐射可导致动物心血管、神经、生殖、免疫等多系统不同程度损伤,严重威胁人类健康,电磁损伤的诊断和防治已成为亟待解决的问题。本文针对电磁辐射对靶器官的损伤作一综述,为电磁辐射的预防、诊断、防治和护理提供依据。 相似文献
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陈家森 《现代生物医学进展》2004,4(2):33-35
随着信息社会的到来 ,电磁波的应用愈来愈广泛 ,愈来愈深入到千家万户 ,因此伴随而来的电磁辐射是否对生命体有影响的问题开始为人们所重视。这一问题的最早出现是西方发达国家的流行病学的调查报告。他们认为美国丹佛 ,克拉拉都州在功率线附近的居民死于白血病的比例较高 ,另外有作者调查得到信息 :一条储有高功率变电站的小街附近发现居民的癌症比例较高的结果 ,甚至有人提出计算机终端及电视机均会给健康带来影响。在移动电话广泛使用的今天 ,有人认为过多的使用会引起脑癌及白血病。在美国还出现波音公司的职工因患癌症而向公司申诉说是… 相似文献
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本文用RGNTF单克隆抗体及抗独特型单克隆抗体的免疫组织化学反应,对RGNTF及其受体在 大鼠体内的分布进行了研究.结果显示,大鼠的肾脏、肾上腺、下颌下腺、胃底腺,以及睾丸的生精细胞对 RGNTIF均呈现强阳性免疫反应,并对RGNTF抗独特型单克隆抗体也呈现阳性免疫反应,表明 RGNTF及其受体有较广泛的分布,这种情况与神经生长因子(NGF)及睫状节神经诱向(营养)因子 (CNTF)相类似.但是,RGNTF及其受体的分布特点和NGF、CNTF的分布是不完全相同的,提示作者 分离的RGNTF与NGF和CNTF不是同源物。这样肾上腺皮质、下颌下腺的浆液腺泡及导管上皮细胞、 胃底腺上皮细胞和生精细胞不仅能够产生RGNTF,也能合成RGNTF受体。因此,它们对RGNTF可能 有自分泌的功能,RGNTF对这些细胞可能有自身调节的效应。 相似文献
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PCR—ELISA在检测血清中丙型肝炎病毒上的应用 总被引:1,自引:0,他引:1
建立了一个替代目前使用的套式PCR的血清中丙型肝炎病毒RNA检测的新方法,该方法只需经过一次PCR扩增,即可通过对掺入标记物的PCR产物的ELISA检测得到与套式PCR相同的结果。与套式PCR相比,该方法具有耗时少、易操作、较少产生假阳性等特点。 相似文献
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建立了一个替代目前使用的套式PCR的血清中丙型肝炎病毒RNA检测的新方法。该方法只需经过一次PCR扩增,即可通过对掺入标记物的PCR产物的ELISA检测得到与套式PCR相同的结果。与套式PCR相比,该方法具有耗时少、易操作、较少产生假阳性等特点。 相似文献
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重组轮状病毒SA11 Vp4抗原表位诱导广泛交叉中和抗体反应 总被引:10,自引:0,他引:10
本文报导在RHV-RNA2载体系统中表达的轮状病毒(RV)Vp4胰酶切割位点区抗原位可诱导动物产生具有广泛交叉中和反应的血清抗体。携带有抗原表位REA、REB和REC,及其组合REA+REB+REC基因的pET重组质粒,高水平表达了这些与载体蛋白嵌合的抗原表位。进一步研究结果表明,这些抗原表位所诱导的动物血清抗体,具有广泛识别同源及异源血清型RV抗原的能力,和体外中和这些同源及异源血清型RV病毒感 相似文献
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正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases 相似文献
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Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme
responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare
the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show
that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by
distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of
demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least
one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of
the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable
potent antiproliferative synthetic drugs. 相似文献
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The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle. 相似文献
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Meng Miao Gang Deng Xiaobei Xiong Yang Qiu Wenda Huang Meng Yuan Fei Yu Shimei Bai Xi Zhou Xiaolu Zhao 《中国病毒学》2022,37(2):314-317
Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions. 相似文献
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions. 相似文献
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Dong Liu Xin Wang Yisong Wang Peigang Wang Dongying Fan Sichang Chen Yuguang Guan Tianfu Li Jing An Guoming Luan 《中国病毒学》2018,33(5):402-409
Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8+ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8+ T cells are involved in the pathogenesis of RE. 相似文献
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Shen Jia-Yuan Li Man Xie Lyu Mao Jia-Rong Zhou Hong-Ning Wang Pei-Gang Jiang Jin-Yong An Jing 《中国病毒学》2021,36(1):145-148
正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016). 相似文献
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Renfei Lu Xiuming Wu Zhenzhou Wan Yingxue Li Lulu Zuo Jianru Qin Xia Jin Chiyu Zhang 《中国病毒学》2020,35(3):344-347
In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans. 相似文献