额凹萤叶甲属一新种：鞘翅目：叶甲科：萤叶甲亚科

本文报道采自武陵山区萤叶甲亚科额凹萤叶甲属Ｓｅｒｍｙｌｏｉｄｅｓ一新种：王氏额凹萤叶甲Ｓ．ｗａｎｇｉ ｓｐ．ｎｏｖ．。     

中国大萤叶甲属的研究（鞘翅目：叶甲科：萤叶甲亚科）

大萤叶甲属Meristata 为Chapuis 1875年所建立,是东洋区分布的属,在我国主要分布在云南和西藏两省,中名以其体大型而得。目前全世界已知11种,中国有9种。本文对本属征进行了重新厘订,并对中国种类做了系统的研究及记述,它们是褐大萤叶甲Meristata dohrni (Baly), 长大萤叶甲Meristata elongata (Jacoby), 黑斑大萤叶甲Meristata fallax (Harold), 黑胸大萤叶甲Meristata fraternalis fraternalis (Baly), 黑胸大萤叶甲云南亚种Meristata fraternalis yunnanensis (Laboissiere), 象牙大萤叶甲Meristata pulunini (Bryant), 四带大萤叶甲Meristata quadrifasciata (Hope), 六斑大萤叶甲Meristata sexmaculata (Kollar et Redtenbacher), 黄腹大萤叶甲Meristata spilota (Hope)。亦对Meristata fraternalis yunnanensis 的分类地位进行了探讨,根据其鞘翅斑点及其雄性生殖器形状将原Meristata yunnanensis 降为Meristata fraternalis 的亚种。     

柱萤叶甲属研究（Ⅱ）五新种记述（鞘翅目：叶甲科：萤叶甲亚科）

本文是柱萤叶甲属研究报告之二,报道了前胸背板黑色的五新种：阿波柱萤叶甲Ｇａｌｌｅｒｕｃｉｄａ ａｐｕｒｖｅｌｌａ ｓｐ．ｎｏｖ．,黑龙江柱萤叶甲Ｇ．ｈｅｉｌｏｎｇｊｉａｎｇａｎａ ｓｐ．ｎｏｖ．,双刻柱萤叶甲Ｇ．ｎｏｔｈｏｒｎａｔａ ｓｐ．ｎｏｖ．,褐足柱萤叶甲Ｇ．ｐｏｓｔｉｆｕｓｃａ ｓｐ．ｎｏｖ．,及凹头柱萤叶甲Ｇ．ｓｏｌｅｎｏｃｅｐｈａｌａ ｓｐ．ｎｏｖ．。     

云南西双版纳地区的萤叶甲（鞘翅目：叶甲科）

本文是云南西双版纳地区萤叶甲亚科区系研究的一部分,记述了３新种及中国３新纪录种,它们分别为：云南萤叶甲Ｇａｌｅｒｕｃａ ｙｕｎｎａｎａ Ｙａｎｇ ｅｔＬｉ,ｓｐ．ｎｏｖ．、毛殊角萤叶Ａｇｅｔｏｃｅｒａ ｓｉｍｉｌｉｓ Ｃｈｅｎ,ｓｐ．ｎｏｖ．、黄胸摹萤叶甲Ｍｕｎｉｎａ ｆｌａｖｉｄａ Ｙａｎｇ ｅｔ Ｙａｏ,ｓｐ．ｎｏｖ．以及罗氏阿波萤叶甲Ａｐｌｏｓｏｎｙｘ ｒｏｂｉｎｓｏｎｉ（Ｊａｃｏｂｙ,１９     

萤叶甲亚科研究I.阿波萤叶甲属的补充描记及二新种记述（鞘翅目：叶甲科）

本文对阿波萤叶甲属的属征作了补充描述，并了采自我国武陵山区的二新种，头阿波萤叶甲及天平山阿波萤叶甲。     

川滇萤叶甲亚科之两新种(鞘翅目:叶甲科)

本文记述萤叶甲亚科两个新种,分隶于凹翅萤叶甲属Paleosepharia Laboissière和隶萤叶甲属Lirotis Weise.前者采自云南贡山,后者采自四川峨眉山。新种模式标本保存在中国科学院动物研究所。     

萤叶甲亚科研究Ⅰ．阿波萤叶甲属的补充描记及二新种记述（鞘翅目：叶甲科）

本文对阿波萤叶甲属Ａｐｌｏｓｏｎｙｘ的属征作了补充描记,并记述了采自我国武陵山区的二新种,黑头阿波萤叶甲Ａ．ｎｉｇｒｉｃｅｐｓｓｐ．ｎｏｖ．及天平山阿波萤叶甲Ａ．ｔｉａｎｐｉｎｇｓｈａｎｅｎｓｉｓｓｐ．ｎｏｖ．。     

柱萤叶甲属三新种及一新纪录种

本文报道了鞘翅目(Coleoptera)叶甲科(Chrysomelidae)萤叶甲亚科(Galerucinae)柱萤叶甲属Gallerucida的三新种:基红柱萤叶甲G.basalis sp.nov.褐缘柱萤叶甲G.limbatella sp.nov.、小柱萤叶甲G.parva sp.nov.及一新纪录种:黑缘柱萤叶甲G.limbata(Baly,1878)。     

武夷山萤甲一新种：（鞘翅目：叶甲科）

本文记述发现于福建武夷山的萤叶甲亚科１新种：棒角日萤叶甲Ｊａｐｏｎｉｔａｔａ ｃｌａｖａｔａ Ｙａｎｇ ｅｔ Ｗｕ,ｓｐ．ｎｏｖ．。新种模式标本存在中国科学院动物研究所     

柱萤叶甲属研究（I）鞘翅具黑色刻点的种类记述：（鞘翅目：叶甲科）

本文就萤叶甲亚科中柱萤叶甲属鞘翅具黑色刻点的种类进行研究,共记述４种,我国已记录３种,其中１种为新种。     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.