共查询到20条相似文献,搜索用时 31 毫秒
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Kannan Tharakaraman Leonardo Mari?o-Ramírez Sergey L Sheetlin David Landsman John L Spouge 《BMC bioinformatics》2006,7(1):408
Background
Many DNA regulatory elements occur as multiple instances within a target promoter. Gibbs sampling programs for finding DNA regulatory elements de novo can be prohibitively slow in locating all instances of such an element in a sequence set. 相似文献3.
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Raffaella Di Lisi Anne Picard Simonetta Ausoni Stefano Schiaffino 《BMC molecular biology》2007,8(1):78
Background
We reported previously that the cardiac troponin I (cTnI) promoter drives cardiac-specific expression of reporter genes in cardiac muscle cells and in transgenic mice, and that disruption of GATA elements inactivates the cTnI promoter in cultured cardiomyocytes. We have now examined the role of cTnI promoter GATA elements in skeletal muscle cells. 相似文献7.
Shlomit Goldman David H Lovett Eliezer Shalev 《Reproductive biology and endocrinology : RB&E》2009,7(1):41
Background
Although the MMP-2 promoter lacks a canonical progesterone response element (PRE), the hormone inhibits MMP-2 expression and is part of treatment protocols in gynecological invasive pathologies, including endometriosis and endometrial hyperplasia. This study aimed to explore the mechanism by which progesterone inhibits MMP-2 expression. 相似文献8.
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Ahamed Khan Ankita Shrestha Kashyap Bhuyan Indu B. Maiti Nrisingha Dey 《Plant molecular biology》2018,96(1-2):179-196
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Background
Many sequenced bacterial genomes harbor phage-like elements or cryptic prophages. These elements have been implicated in pathogenesis, serotype conversion and phage immunity. The e14 element is a defective lambdoid prophage element present at 25 min in the E. coli K-12 genome. This prophage encodes important functional genes such as lit (T4 exclusion), mcrA (modified cytosine restriction activity) and pin (recombinase). 相似文献12.
Muriel Gaillard Nicolas Pradervand Marco Minoia Vladimir Sentchilo David R Johnson Jan Roelof van der Meer 《BMC microbiology》2010,10(1):153
Background
Integrative and conjugative elements (ICE) form a diverse group of DNA elements that are integrated in the chromosome of the bacterial host, but can occasionally excise and horizontally transfer to a new host cell. ICE come in different families, typically with a conserved core for functions controlling the element's behavior and a variable region providing auxiliary functions to the host. The ICEclc element of Pseudomonas knackmussii strain B13 is representative for a large family of chromosomal islands detected by genome sequencing approaches. It provides the host with the capacity to degrade chloroaromatics and 2-aminophenol. 相似文献13.
Hwang Y.-S. Karrer E.E. Thomas B.R. Chen L. Rodriguez R.L. 《Plant molecular biology》1998,36(3):331-341
Expression of -amylase genes during seedling development plays a key role in production of sugar from the starch stored in the cereal seed. Rice -amylase Amy3D promoter/GUS constructs in transgenic rice cell lines were studied to identify cis elements in the promoter of this metabolite-regulated gene. Three sequences having the greatest effects on Amy3D gene expression included the amylase element (TATCCAT), the CGACG element, and a G box-related element (CTACGTGGCCA). These promoter cis elements are needed for high-level expression of Amy3D under conditions of sugar starvation. The involvement of G box cis-elements in environmental stress responses suggest a link between the nutrient stress and the environmental stress responses of the plant. 相似文献
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Bruce Hopenfeld 《Biomedical engineering online》2006,5(1):60-14
Background
In some cases, it may be necessary to combine distinct finite element meshes into a single system. The present work describes a scheme for coupling a finite element mesh, which may have curvilinear elements, to a voxel based finite element mesh. 相似文献18.
Background
Numerous completely sequenced bacterial genomes harbor prophage elements. These elements have been implicated in increasing the virulence of the host and in phage immunity. The e14 element is a defective lambdoid prophage element present at 25 min in the Escherichia coli K-12 genome. e14 is a well-characterized prophage element and has been subjected to in-depth bioinformatic analysis. 相似文献19.