神蕊螨属一新种述：（蜱螨亚纳：长须螨科）

本文记述神蕊螨属Ａｇｉｓｔｅｍｕｓ Ｓｕｍｍｅｒｓ一新种,黄山神蕊螨Ａｇｉｓｔｅｍｕｓ ｈｕａｎｇｓｈ－ａｎｅｎｓｉｓ ｓｐ．ｎｏｖ。     

植绥螨科四新种记述（蜱螨亚纲：植绥螨科）

本文记述植绥螨科４新种：长囊钝绥螨Ａｍｂｌｙｓｅｉｕｓ ｌｏｎｇｉｓａｃｃａｔｕｓ ｓｐ．ｎｏｖ．,钩囊钝绥螨Ａ．ｓｔｒｏｂｏｃｏｒｙｃｕｓ ｓｐ．ｎｏｖ．,新裴济钝绥螨Ａ．ｎｅｎｆｉｊｉｅｎｓｉｓ ｓｐ．ｎｏｖ．及侧膜盲走螨Ｔｙｐｈｌｏｄｒｏｍｕｓ ｌａｔｅｒｉｓ ｓｐ．ｎｏｖ．。     

曲美绥螨雄螨和洮儿河美绥螨前若螨描述（蜱螨亚纲：革螨股：美绥螨科）

描述曲美绥螨Ａｍｅｒｏｓｅｉｕｓ ｃｕｒｖａｔｕｓ Ｇｕ．Ｗａｎｇ ｅｔ Ｂａｉ,１９８９雄螨和洮儿河美绥螨Ａｍｅｒｏｓｅｉｕｓ ｔａｏｅｒｈｅｎｓｉｓ,Ｍａ,１９９５前若螨。     

广西瘤瘿螨属四新种记述：蜱螨亚纲：瘿螨科

４个新种是紫薇瘤瘿螨Ａｃｅｒｉａ ｌａｇｅｒｓｔｒｏｅｍｉａｅ Ｋｕａｎｇｅｔ Ｙａｎｇ,ｓｐ．ｎｏｖ．,路边青瘤瘿螨Ａｃｅｒｉａ ｇｅｉ Ｋｕａｎｇ ｅｔＬｕ,ｓｐ．ｎｏｖ．,广西瘤瘿螨Ａｃｅｒｉａ ｇｕａｎｘｉｅｎｓｅ ＫｕａｎｇｅｔＬｕ,ｓｐ．ｎｏｖ．和梧州瘤瘿螨Ａｃｅｒｉａ ｗｕｚｈｏｕｅｎｓｉｓ Ｋｕａｎｇｅｔ Ｙａｎｇ,ｓｐ．ｎｏｖ。     

湖北阳厉螨属一新种(蜱螨亚纲:革螨股:厉螨科)

记述阳厉螨属１新种,即叉阳厉螨Ａｎｄｒｏｌａｅｌａｐｓｔｒｉｆｕｒｃａｔｏｉｄｅｓｓｐ．ｎｏｖ．。     

青海省阳厉螨属一新种：蜱螨亚纲：厉螨科

本文记述从青海省湟中长尾仓鼠Ｃｒｉｅｃｔｕｌｕｓ ｌｏｎｇｉｃａｕｄａｔｕｓ巢中采得的阳厉螨属一新种,即九棘阳厉螨Ａｎｄｒｏｌａｅｌａｐｓ ｎｏｖｅｍｓｐｉｎｏｓｕｓ ｓｐ．ｎｏｖ。新种与三叉阳厉螨Ａ．ｔｒｉｆｕｒｃａｔｕｓ Ｗａｎｇ ｅｔ ＬｉＲＵＶ ＲＰ     

中国叶刺瘿螨亚科四新种记述(蜱螨亚纲:瘿螨总科)

文内新种为樱花刺皮瘿螨Ａｃｕｌｏｐｓ ｙｉｎｇｈｕａｅ Ｋｕａｎｇ,ｓｐ．ｎｏｖ。,西宁刺皮瘿螨Ａｃｕｌｏｐｓ ｘｉｎｉｎｇｅｎｓｉｓ Ｋｕａｎｇ,ｓｐ．ｎｏｖ．,湟中刺瘿螨Ａｃｕｌｕｓ ｈｕａｎｇｚｈｏｎｇｅｎｓｉｓ Ｋｕａｎｇ,ｓｐ．ｎｏｖ．和白英叶刺瘿螨Ｐｈｙｌｌｏｃｏｐｔｅｓ ｓｏｌａｎｉ Ｋｕａｎｇ,ｓｐ．ｎｏｖ．。     

吉林省美绥螨属2新种（蜱螨亚纲：美绥螨科）

报道美绥螨属２新种：崔氏美绥螨Ａｍｅｒｏｓｅｉｕｓｃｕｉｑｉｓｈｅｎｇｉｓｐ．ｎｏｖ和洮儿河美绥螨Ａｍｅｒｏｓｅｉｕｓｔａｏｅｒｈｅｎｓｉｓｓｐ．ｎｏｖ采自吉林省白城的腐烂树皮下。     

云南土壤甲螨二新种（蜱螨亚纲：甲螨亚目：小隅甲螨科,步甲螨科）

本文记述土壤甲螨二新种：弯毛小隅甲螨Ｍｉｃｒｏｔｅｇｅｕｓ ｃｕｒｖｉｓｅｔｏｓｕｓ ｓｐ．ｎｏｖ．,大叶原步甲螨Ａｒｃｈｅｇｏｃｅｐｈｅｕｓ ｍａｃｒｏｆｏｌｉａｔｕｓ ｓｐ．ｎｏｖ．。模式标本存于白求恩医科大学生物教研室。     

中国瘿螨科三新种记述(蜱螨亚纲:瘿螨总科)

记述瘿螨科Ｅｒｉｏｐｈｙｉｄａｅ３新种：瘿螨亚科Ｅｒｉｏｐｈｙｉｄａｅ的相瘤瘿螨Ａｃｅｒｉａ ｃｅｌｔｉｄｉｓ Ｚｈａｏ ｅｔ Ｋｕａｎｇ,ｓｐ．ｎｏｖ．;叶刺瘿螨亚科Ｐｈｙｌｌｏｃｏｐｔｉｎａｅ的无花果中瘿螨Ｓｉｎａｃｕｓ ｃａｒｉｃａｅＺｈａｏ ｅｔ Ｋｕａｎｇ,ｓｐ．ｎｏｖ．和柳顶冠瘿螨Ｔ ｅｇｏｌｏｐｈｕｓ ｓａｌｉｃｉｓ Ｋｕａｎｇ ｅｔ Ｚｈａｏ,ｓｐ．ｎｏｖ．。display structure     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.