山东宁阳早更新世哺乳动物化石(英文)

１９９９年,作者收到王元青博士转来胡长康老师未研究的一批哺乳动物化石。这些化石由山东省博物馆工作人员采自山东宁阳县伏山的裂隙堆积物中。根据化石围岩判断这批化石可归入同一动物群。该动物群包含１２种：松鼠科１种（Ｓｃｉｕｒｏｔａｍｉａｓ　ｓｐ．）,兔科２种（Ｂｒｅｖｉｌａｇｕｓ ｂｒａｃｈｙｐｕｓ,Ｌｅｐｕｓ ｓｐ．）,食肉目５种（Ｐａｃｈｙｃｒｏｃｕｔａ ｐｅｒｒｉｅｒｉ,Ｎｙｃｔｅｒｅｕｔｅｓ　ｓｉｎｅｎｓｉｓ,Ｃａｎｉｓ ｖａｒｉａｂｉｌｉｓ, Ｈｏｍｏｔｈｅｒｉｕｍ ｓｐ．和Ｍｅｌｅｓ ｓｐ．）,牛科２种（Ｇａｚｅｌｌａ ｓｐ．, Ｏｖｉｂｏｖｉｎａｅ ｇｅｎ ｅｔｓｐ．ｉｎｄｅｔ．）,鹿科２种（Ｃｅｒｖｕｓ　ｓｐ．,Ｃｅｒｖｉｄａｅ　ｇｅｎ　ｅｔ　ｓｐ．ｉｎｄｅｔ．）。其中,Ｐａｃｈｙｃｒｏｃｕｔａ　ｐｅｒｒｉｅｒｉ个体明显小于桑氏鬣狗（Ｐａｃｈｙｃｒｏｃｕｔａ ｌｉｃｅｎｔｉ）,ｐ２后附尖较发育,ｐ４前附尖高,ｍｌ三角座窄。四川巫山原鉴定为桑氏鬣狗的标本中至少有一件下颌骨（重庆自然博物馆,ＣＶ８７７）应当归入此种。Ｍｅｌｅｓ ｓｐ．具有较周口店第１８点发现的Ｍｅｌｅｓ ｃｈｉａｉ及中更新世常见的Ｍｅｌｅｓ　ｍｅｌ?     

广西十大功劳属(小檗科)一新种

小叶十大功劳新种图１ＭａｈｏｎｉａｍｉｃｒｏｐｈｙｌａＴ．Ｓ．ＹｉｎｇｅｔＧ．Ｒ．Ｌｏｎｇ,ｓｐ．ｎｏｖ．Ｆｉｇ．１Ｓｐｅｃｉｅｓｖａｌｄｅｉｎｓｉｇｎｉｓｆｏｌｉｏｌｉｓ１０～１４ｊｕｇｉｓ,ｍａｒｇｉｎｅｉｎｔｅｇｒｉｓ,２．５～３．５ｃｍｌｏ...     

新疆准噶尔盆地中生代直脉科(昆虫纲,长翅目)昆虫化石

描述了采自新疆准噶尔盆地克拉玛依吐孜沟下侏罗统八道湾组和乌苏县四棵树煤矿之南哈尔沙拉上三叠统小泉沟群直脉科昆虫化石１０种。它们被归入３属，其中５种为新种，即：Ｏｒｔｈｏｐｈｌｅｂｉａｅｘｃｕｌｐｔａｓｐ．ｎｏｖ．，Ｏ．ｃｏｌｏｒａｔａｓｐ．ｎｏｖ．，Ｍｅｓｏｐａｎｏｒｐａｄｅｎｓａｓｐ．ｎｏｖ，Ｍ．ｍｏｎｓｔｒｏｓａｓｐ．ｎｏｖ．和Ｐｒｏｔｏｒｔｈｏｐｈｌｅｂｉａｓｔｒｉｇａｔａｓｐ．ｎｏｖ．。对中国的直脉科昆虫进行了详细的讨论。     

安徽淮南下寒武统馒头组的遗迹化石

产于安徽淮南下寒武统馒头组上部浅水台地相灰岩和棕褐色页岩中的遗迹化石鉴定为５属５种,包括１新种,它们是Ｂｅａｃｏｎｉｃｈｎｕｓ ｉｃｈｎｏｓｐ．Ｄｉｐｌｉｃｈｎｉｔｅｓ ｉｃｈｎｏｓｐ．,Ｐｈｏｅｂｉｃｈｎｕｓ ｍｉｎｏｒ ｉｃｈｎｏｓｐ．ｎｏｖ．,Ｔｈａｌａｓｓｉｎｎｏｄｅｓ ｈｏｒｉｚｏｎｔａｌｉｓ Ｍｙｒｏｗ,１９９５和Ｈｅｌｍｉｎｔｈｏｉｄａ ｉｎｄｅｔ．ｉｃｈｎｏｓｐ．。对它们的形成方式     

携带p53基因的重组腺病毒的构建及对肿瘤细胞抑制的研究

１　材料与方法１１　质粒ｐＣＭＶｐ５３ＢＡＭ由美国约翰·霍普金斯肿瘤中心ＢｅｒｔＶｏｇｅｌｓｔｅｉｎ教授赠送［５］;ｐＲＳｅｔＡ购于Ｉｎｖｉｔｒｏｇｅｎ公司;ｐＣＡ１３和ｐＢＨＧ１１为ＭｉｃｒｏｂｉｘＢｉｏｓｙｓｔｅｍＩｎｃ．产品。ｐＢＨＧ１１包含腺病毒Ａｄ５基因组３６ｋｂ中的约３４ｋｂ序列,但Ａｄ５Ｅ１区１８８ｂｐ至１３３９ｂｐ缺失,代之以氨苄青霉素抗性基因和复制起始位点。ｐＢＨＧ１１缺少包装信号φ（２２ｂｐ至３４２ｂｐ）和Ａｄ５Ｅ３区（２７８６５ｂｐ至３０９９５ｂｐ序列）。ｐＣＡ１３…     

内蒙古始新世梳趾鼠类化石

描述了４属１０种梳趾鼠类化石（Ｇｏｂｉｏｍｙｓ ｎｅｉｍｏｎｇｏｌｅｎｓｉｓ, Ｇ． ｅｘｉｇｕｕｓ（新种）, Ｇ． ｃｆ．Ｇ．ｅｘｉｇｕｕｓ,Ｇ．ａｓｉａｔｉｃｕｓ（新种）,Ｇｏｂｉｏｍｙｓ？ｓｐｐ．,Ａｄｖｅｎｉｍｕｓ　ｃｆ．Ａ．ｂｏｈｌｉｎｉ,Ａ．ｃｆ．Ａ．ｂｕｒｋｅｉ, Ｙｕｏｍｙｓ ｓｐ．和Ｐｒｏｔａｔａｒｏｍｙｓ　ｓｐ．）．以Ｍｅｒｇｅｎｏｍｙｓ　ｎｅｉｍｏｎｇｏｌｅｎｓｉｓ作属型种建了一新属,Ｇｏｂｉｏｍｙｓ。其特征是：门齿孔大;具Ｐ３;颊齿齿冠低,主尖明显,但不膨大,齿凹开阔;Ｐ４／ｐ４非臼齿化;上臼齿宽大于长,后脊较发育;Ｍ１和Ｍ２具内脊;下外脊和下次小尖位置偏外。Ｇ．ｅｘｉｇｕｕｓ的特点是：个体较小,上颌骨颧突根在Ｐ３之前,下臼齿缺下原失后臂舌部、下内尖臂和下前齿带．Ｇ．ａｓｉａｔｉｃｕｓ的上颌骨颧突后缘在Ｐ３的外方;臼齿具较发达的齿脊;上臼齿较宽短,后小尖较弱;下臼齿具较发达的内尖臂和前齿带。 Ｇｏｂｉｏｍｙｉｄａｅ新科包括Ｇｏｂｉｏｍｙｓ, Ｍｅｒｇｅｎｏｍｙｓ,Ｙｏｕｎｇｏｍｙｓ和哈萨克斯坦的未命名的新属等４属,组成与梳趾鼠科相对的姐妹群。其主要特征是,下颌骨缺咬肌窝上嵴。颊齿低冠,近于丘形     

吐鲁番盆地鄯善地区中、晚侏罗世介形类

报道吐鲁番盆地连木沁剖面七克以组及齐古组的介形类化石３属１０种,其中２新种１未定种;Ｔｈｅｒｉｏｓｙｎｏｅｃｕｍ？ｑｉｋｔｉｍｅｎｓｉｓ ｓｐ．ｎｏ。,Ｔｈ．ｈｕｏｙａｎｓｈａｎｅｎｉｓ ｓｐ．ｎｏｖ．,Ｄａｒｗｉｎｕｌａ ｓｐ．,根据化石组合面貌,自上而下可建立两个组合,即Ｄａｒｗｉｎｕｌａ－Ｍｅｔａｃｙｐｒｉｓ组合和Ｔｈｅｒｉｏｓｙｎｏｅｃｕｍ？－Ｄａｒｗｉｎｕｌａ组合,其时代分别为晚侏罗世和     

榆社盆地第三纪晚期的Gazella羚羊

重新研究山西榆社盆地新第三纪晚期和第四纪早期的Ｇａｚｅｌｌａ羚羊。依据综合的分类标志，在种的水平上对它进行修正；三个新种被建立，它们是Ｇ．ｇａｏｚｈｕａｎｇｅｎｓｉｓ ｓｐ．ｎ，Ｇ．要和Ｇ．ｎｉｈｅｎｓｉｓ ｓｐ．ｎ．。根据头骨、角头和牙齿的形态特征，推测在该地马会组至海眼组中存在着Ｇａｚｅｌｌａ的两条演化线。Ｇ．ｇａｕｄｒｙｉ可能是它们的祖先类型。     

中国尾孢菌属及其近似属的研究Ⅱ.

５种尾孢菌和２种假尾孢菌,其中有３个新种：杜若尾孢Ｃｅｒｃｏｓｐｏｒａ ｐｏｌｌｉａｅ－ｊａｐｏｎｉｃａｅＹ．Ｌ．Ｇｕｏ＆Ｙ．Ｊｉａｎｇ,ｓｐ．ｎｏｖ．,日本锦带花尾孢Ｃ．ｗｅｉｇｅｌａｅ－ｊａｐｏｎｉｃａｅＹ．Ｌ．Ｇｕｏ＆Ｙ．Ｊｉａｎｇ,ｓｐ．ｎｏｖ．和旋覆花假尾孢Ｐｓｅｕｄｏｃｅｒｃｏｓｐｏｒａ ｉｎｕｌａｅＹ．Ｌ．Ｇｕｏ＆Ｙ．Ｊｉａｎｇ,ｓｐ．ｎｏｖ．,１个新组合：紫菀假尾孢Ｐｓｅｕｄｏｃｅ     

昆明附近早寒武世遗迹化石

报道了昆明地区下寒武统筇竹寺组玉案山段和沧浪铺组乌龙箐段所发现的遗迹化石共１３属１５种，其中１新属６新种为：ＱｉｐａｎｓｈａｎｉｃｈｎｕｓｇｙｒｕｓＬｕｏｅｔＴａｏｉｃｈｎｏｇｅｎ．ｅｔｉｃｈｎｏｓｐ．ｎｏｖ．，ＡｒｔｈｒｏｐｈｙｃｕｓｑｉｏｎｇｚｈｕｓｉｅｎｓｉｓＬｕｏｉｃｈｎｏｓｐ．ｎｏｖ．，ＢｉｆｕｎｇｉｔｅｓｋｕｎｙａｎｇｅｎｓｉｓＬｕｏｉｃｈｎｏｓｐ．ｎｏｖ．，ＣｒｕｚｉａｎａｂｅｉｆｅｎｇｗａｎｅｎｓｉｓＬｕｏｅｔＧａｏｉｃｈｎｏｓｐ．ｎｏｖ．，ＰａｌａｅｏｐｈｙｃｕｓｂｅｉｆｅｎｇｗａｎｅｎｓｉｓＬｕｏｉｃｈｎｏｓｐ．ｎｏｖ．，ＡｒｃｈａｅｉｃｈｎｉｕｍｋｕｎｍｉｎｇｅｎｓｉｓＬｕｏｉｃｈｎｏｓｐ．ｎｏｖ．。这些遗迹化石均产于开阔台地相潮下带的低能环境，为浅海相的Ｇｒｕｚｉａｎａ遗迹相。     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

鸡传染性法氏囊病病毒研究进展

传染性法氏囊病(Infection bursal disease, IBD)是由鸡传染性法氏囊病毒(Infectious bursal disease virus, IBDV)引起的鸡和火鸡的一种高度接触性传染病,给世界各国的禽养殖业带来了巨大损失.自IBDV发现至今新的变异株不断出现,分子结构的改变导致病毒致病力的改变及宿主对疫苗应答的改变,使得传统的疫苗已不能控制其流行,因此各国学者对其基因组结构和功能进行了广泛深入的研究,并积极研制新型有效的疫苗以达到防治的目的.     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.