滑绥螨属一新种（蜱螨亚纲：革螨股：裂胸螨科）

记述滑绥螨属1新种：长毛骨绥螨Leioseius dolichotrichus,sp.nov.,模式标本保存于吉林省白城市全国鼠疫布氏菌病防治基地。     

宁夏角绥螨属一新种(蜱螨亚纲,囊螨科)

记述囊螨科Ascidae角绥螨属Antennoseius Berlese,1916一新种,宁夏角绥螨Antennoseius ningxiaensis sp.nov..标本采自宁夏回族自治区中卫县红泉乡蚂蚁Myrmos sp.巢穴内,保存于军事医学科学院微生物流行病研究所医学昆虫标本馆.文内测量单位均为μm.     

美绥螨属一新种(蜱螨亚纲,美绥螨科)

记述美绥螨科Ameroseiidae美绥螨属Ameroseius Berlese,19031新种,青海美绥螨Ameroseius qinghaiensis sp.nov.,新种与曲美绥螨Ameroseius curvatus Gu,Wang et Bai,1989近似,但有明显区别。模式标本采自青海省湟中县总寨乡褐家鼠Rattus norvegicus和长尾仓鼠Cricetulus longicaudatus体上,保存于青海省地方病预防控制所。     

毛绥螨属一新种(蜱螨亚纲,裂胸螨科)

记述裂胸螨科Aceosejidae毛绥螨属Lasioseius Berlese,1916一新种,多毛毛绥螨Lasioseius multisetus sp.nov..标本采自宁夏回族自治区银川市南郊天牛洞道,保存于军事医学科学院微生物流行病研究所医学昆虫标本馆.文内测量单位均为μm.     

中国钝螨属一新种和肛厉螨属一新纪录(蜱螨亚纲,寄螨科,裂胸螨科)

记述钝革螨属Amblygamasus Berlese,1904 1新种,龚氏钝革螨,新种Amblygamasus gongzhengdai sp.nov.,和肛厉螨属Proctolaelaps Berlese,1923中国新纪录,长毛肛厉螨Proctolaelaps longipilis(Chant,1958),标本采自银川市花卉市场,模式标本保存于军事医学科学院微生物流行病研究所昆虫标本馆,北京.     

裂胸螨科4新种和中国2新纪录属：蜱螨亚纲：革螨股

记述裂胸螨科4新种:陈氏毛绥螨Lasioseius chenpengi sp.nov.,杵状肛厉螨Proctolaelaps pis-tilli sp.nov.,疏毛北绥螨Arctoseius oligotrichus sp.nov.和巨肛伊(虫穴)螨中Iphidozercon magnanalis sp.nov.。其中北绥螨属Arctoseius Thor,1930和伊(虫穴)螨属Iphidozercon Berlese,1903为中国首次纪录。     

广厉螨属一新种(蜱螨亚纲,厉螨科)

记述厉螨科Lealapidae Berlese,1892广厉螨属Cosmolaelaps Berlese,1892 1新种,即网纹广厉螨Cosmolaelaps retirugi sp.nov..标本采自青海省西宁市湟中县总寨地区褐家鼠Rattus norvegicus体上.模式标本存放在青海省地方病预防控制所,文内测量单位均为μm.     

中国革螨2新记录（蜱螨亚纲：裂胸螨科，角绥螨科）

报道中国革螨2新记录：半裂北绥螨Arctoseius semiseissus（Berlese,1892）和奥氏角绥螨Antennoseius oudemansi（S．Thor,1930）。     

中国厚厉螨科二新种(蜱螨亚纲,中气门亚目)(英文)

记述厚厉螨科2新种:长白厚厉螨Pachylaelaps changbaiensis sp.nov.和桓仁厚绥螨Pachyseius huanrenensis sp.nov.,模式标本保存于辽宁省沈阳农业大学植物保护学院.     

中国手绥螨属一新种和足角螨属一新纪录种(蜱螨亚纲,中气门亚目,裂胸螨科,足角螨科)

记述裂胸螨科手绥螨属1新种凤凰手绥螨Cheiroseius fenghuangensis sp.nov.和足角螨科足角螨属一中国新纪录种青木足角螨Podocinum aokii Isikawa,1970,模式标本保存于辽宁省沈阳农业大学植物保护学院.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.