纤恙螨属恙螨一新种：蜱螨亚纲：恙螨科

从采自新疆博乐县阿拉山口(海拔290 m)室内灰仓鼠伏龙芝亚种 Cricetulus migratorius caesius耳壳内的一批纤恙螨标本鉴定中发现中国新记录亚属——爱柯纤恙螨亚属 Ericotrombidium中的一个新种,定名为博乐纤恙螨 Leptotrombidium (E.) bolei sp.nov.,它与美丽纤恙螨L.(E.)pulchrum(Sosnina,1950)及索氏纤恙螨L.(E.)sokolovi Kudryshova,1984比较近似,但本新种IP及盾板量度除 AM外均较大,PW-SB≥PL,可与前者区别;IP较小,平均787,幅度763—821,DS较少,排列规则:2+8.6.6.4.2=28,可与后者区别。     

江西省纤恙螨属二新种（蜱螨亚纲：恙螨科）

本文报道采自江西省武功山和庐山地区的纤恙螨属二新种:武功纤恙螨Lepfotrombidium (L.)wugongensis和庐山纤恙螨Leptotrombidium(L.)lushaneusis,并对该新种的形态特征作了详细描述,与近似种湖北纤恙螨 Leptatrombidium(L.)hupeca(Ma et Hsu)1965和曲靖纤恙螨Leptotrombidium(L.)quiingensis(Yu et al.)1981进行了分析比较。     

青海省纤恙螨属三新种（蜱螨亚纲：恙螨科）

本文描述采自青海的纤恙螨属Ｌｅｐｔｏｔｒｏｍｂｉｄｉｕｍ Ｎａｇａｙｏ ｅｔ ａｌ,１９１６,三个新种;巴颜纤恙螨Ｌ．（Ｌ．）ｂａｙａｎｅｎｓｉｓ ｓｐ．ｎｏｖ。,川纤恙螨Ｌ．（Ｌ．）ｈｕａｎｇｃｈｕａｎｅｎｓｉｓ ｓｐ．ｎｏｖ．,乌兰纤恙螨Ｌ．（Ｌ．）ｗｕｌａｎｅｎｓｉｓ ｓｐ．ｎｏｖ．模式标本均保存在青海省地方病防治研究所。     

辽宁省恙螨生态地理分布

辽宁省已知恙螨25种,分属于2科3亚科10属。本文依据四个不同地理景观区内恙螨的优势种、常见种和罕见种,对其生态地理分布作了讨论。(1)辽东山地及半岛丘陵区：有恙螨22种。其中东方纤恙螨为优势种;姬鼠纤恙螨、仓纤恙螨、林姬纤恙螨、皆貌纤恙螨、塔米新恙螨、鸡新棒恙螨等为罕见种.(2)辽河平原区：有恙螨8种。优势种为须纤恙螨;辽姬纤恙螨为罕见种。(3)辽西低山丘陵区：有恙螨8种。其中高丽新恙螨为优势种;凹邃合轮恙螨、膜嗜翼手恙螨等为罕见种。(4)黄土丘陵台地干草原区：有恙螨2种,均为常见种,其中脆弱无前恙螨数量较多。     

昆明西山纤恙螨一新种：真螨目：恙螨科

1958年在昆明西山采得1种恙螨,经鉴定系1新种,定名为昆西纤恙螨,标本保存在昆明军事医学研究所。昆西纤恙螨Leptotrombidlum(L.)kunxi Xiang et Wen,新种(图1-6) 标本:正模、幼虫,昆明西山,海拔2110m,1958-Ⅸ-26,向容炯、陈祖武采,宿主为普通树鼩中华亚种Tupaia glis chinenis,寄生在肛门周围。 鉴别:本新种与纤恙螨属的Leptotrombidium(L.)pesudofulmentum V.-G.et     

纤恙螨属一新种：真螨目：恙螨科

本文报道1983年采自吉林省和龙县棕背(鼠平) Clethrionomys rufocanus 体上的一种新恙螨,棕(鼠平)纤恙螨 Leptotrombidium rufoconum sp.nov,模式标本分别存放福建医学院寄生虫学教研室和沈阳军区后勤部军事医学研究所。     

纤恙螨属一新种(蜱螨亚纲,恙螨科)

记述纤恙螨属Leptotrombidium Nagayo et al．,1916 1新种,即尖扎纤恙螨Leptotrombidium(L．) jianzhaensis sp．nov．,标本采自青海省黄南州尖扎县坎布拉地区红耳鼠兔Ochotona erythrotis体上。模式标本存放在青海省地方病预防控制所。文内量度单位均为μm。     

恙螨子代幼虫群体形态在分类上的应用

采自湖南吉首和福建永定的两群形态相似的纤恙螨在实验室中饲养。将它们1雌1雄进行配对。当幼虫孵出后测量并比较其体各部的测量数,同时将其成虫与地里纤恙螨成虫酯酶同工酶酶谱进行比较。结果表明此两群形态相似的纤恙螨系英帕纤恙螨(Leptotrombidium imphalum)的不同地理亚种,它们形态与福建东部地区恙虫病媒介微红纤恙螨十分相似。恙螨子代幼虫群体形态的测量数系恙螨分类中的主要参数。     

五种恙螨染色体核型的研究

恙螨染色体的研究迄今仅Shirai等(1984)简要地报道了三种纤恙螨的染色体核型。本实验采用压片法和改良空气干燥法,研究观察五种恙螨有丝分裂染色体核型。初静止化蛹1—3天的成蛹阶段是制作恙螨有丝分裂染色体标本的最佳虫期。微红纤恙螨,地里纤恙螨和巨螫齿恙螨染色体数目为2n=14;苍白纤恙螨和小板纤恙螨为2n=16。染色体呈大小不等的小棒状,单着丝粒,但多不清晰,仅可见着丝点区浅染。部分核型出现染色体异型现象。核型性别未明,性别决定机制不清。     

纤恙螨属一新种(蜱螨亚纲,恙螨科)

记述纤恙螨属Leptotrombidium Nagayo et al.,19161新种,拟六毛纤恙螨Leptotrombidium(L.)subsexsetum Ma,Baiet Feng,sp.nov.,模式标本采自宁夏回族自治区六盘山自然保护区洮州绒鼠Cargomgseva Thomas,1911体,保存于军事医学科学院微生物流行病研究所医学昆虫标本馆。     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

鸡传染性法氏囊病病毒研究进展

传染性法氏囊病(Infection bursal disease, IBD)是由鸡传染性法氏囊病毒(Infectious bursal disease virus, IBDV)引起的鸡和火鸡的一种高度接触性传染病,给世界各国的禽养殖业带来了巨大损失.自IBDV发现至今新的变异株不断出现,分子结构的改变导致病毒致病力的改变及宿主对疫苗应答的改变,使得传统的疫苗已不能控制其流行,因此各国学者对其基因组结构和功能进行了广泛深入的研究,并积极研制新型有效的疫苗以达到防治的目的.     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.