苏铁蕨的化学成分

从蕨类植物苏铁蕨( Brainea insignis) 中分离得到1 个新的苯乙烯基吡喃酮苷, 利用波谱技术鉴定了其结构。此外, 还得到了1 个已知的苯乙烯基吡喃酮苷和4 个其它已知化合物。同时, 还测定了分离得到的两个苯乙烯基吡喃酮苷化合物的DPPH 自由基清除活性。     

清香木姜子的化学成分

从清香木姜子（Litsea euosma W．W．Smith）的枝叶中分离得到1个新化合物-α-吡喃酮衍生物（1）以及3个已知化合物：阿魏酸酯衍生物（2）,6-氧-棕榈酰-β-胡萝卜甙（3）和葡萄糖（4）,经波谱学鉴定新化合物α-吡喃酮衍生物的结构为：5-经基-6-甲基-3-（10-十一烯基）-5,6-二氢吡哺-2-酮。     

鹿蹄草化学成分研究

从鹿蹄草(Pyrola callianthaH.Andres)中分离得到11个化合物,经光谱分析确定其结构为(4R)-1-四氢萘酮(1),(4S)-1-四氢萘酮(2),夹竹桃麻素(3),没食子酸(4),3,4-二羟基苯甲酸(5),鹿蹄草素(6),5-羟甲基糠醛(7),金丝桃苷(8),2″-O-没食子酰基金丝桃苷(9),鹿蹄草苷B(10),4-羟基-2,7-二甲基萘基-1-O-β-D-吡喃葡萄糖苷(11)。其中化合物1,2,3,5,6,11为首次从该植物中分离得到,化合物7为首次从该属中分离得到。     

牛筋条的新化合物

从牛筋条（Dichotomanthes tristaniaecarpa)地上部分分离得到8个化合物,经^1HNMR,^13CNMR,MS等波谱分析,它们被分别鉴定为羽扇豆醇（1）,白桦脂醇（2）,5,7-二羟基色酮（3）,（-）-表儿茶素（4）,圣草酚3′-O-β-D-葡萄糖苷（5）,圣草酚7-O-β-D-（6′-乙酯基）-吡喃葡萄糖醛酸苷（6）,圣草酚7-O-β-D-（6′-甲酯基）-吡喃葡萄糖醛酸苷（7）,野蔷薇苷（8）,其中化合物6,7为新化合物。     

脱脂亚麻籽的化学成分研究(英文)

从脱脂亚麻籽(Linum usitatissimum L.)中共分离出8个化合物,经过波谱分析确定其结构分别是:正二十四烷(1),十四烷酸(2),硬脂酸(3),月桂酸乙酯(4),β-谷甾醇(5),胡萝卜苷(6),α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖(7)和α-D-吡喃葡萄糖基-β-呋喃果糖(8).化合物1,2,4,7,8首次从亚麻籽中分离得到.     

秃叶黄皮树叶子的化学成分研究(英文)

从秃叶黄皮树叶子(Phellodendron chinensevar.glabriusculumSchneid)分离到7个化合物,经波谱解析鉴定为6-O-乙酰基黄柏苷(1),6-O-乙酰基二氢黄柏苷(2),(2R)-4′,5-二羟基-7-O-β-D-吡喃葡萄糖基-8-异戊烯基-二氢黄酮(3),黄柏苷(4),2-O-β-D-吡喃葡萄糖基-6-羟基-苯甲酸苄酯(5),柑橘素C(6),3-羰基齐墩果烷(7),其中化合物1～3,5～7为首次从秃叶黄皮树叶子中分离得到。     

鞭打绣球中的一个新单萜苷

从鞭打绣球(Hemiphragma　heterophyllum　Wall.)全草中分离到1个新单萜苷和7个已知化合物。通过波谱数据分析,新单萜苷的结构鉴定为(4S)-α-萜烯醇-8-O-β-D-吡喃木糖-(1→6)-β-D-吡喃葡萄糖苷,已知化合物分别鉴定为globularin　(2)、(2S,　3S,　4R,　9E)-1,　3,　4-trihydroxy-2-[(2'R)-hydroxy-tetracosanoylamino]-9-octadecene　(3)、　β-香树素(4)、齐墩果酸　(5)、肉桂酸　(6)、β-谷甾醇　(7)和胡萝卜甙　(8)。除化合物2外,其余化合物均为首次从鞭打绣球中分离得到。     

玫瑰红景天化学成分研究

采用大孔吸附树脂、硅胶柱、ADS-5C反相柱和制备HPLC色谱技术对新疆产玫瑰红景天根茎中的植物化学成分进行提取分离和纯化研究,从中分离得到15个化合物。通过理化方法及1H、13C NMR等方法鉴定为:对-O-β-吡喃葡萄糖基-苯-2-丁酮(1)、6’-O-没食子酰-红景天苷(2)、对-O-β-吡喃葡萄糖基-苯丙烯酸(3)、7-甲氧基香豆素(4)、表没食子儿茶素-3-没食子酸酯(5)、苯乙基-6-O-β-葡萄糖苷(6)、对羟基苯甲酸(7)、红景天苷(8)、肉桂醇-6’-O-α-吡喃阿拉伯糖基-O-β-吡喃葡萄弹苷(9)、肉桂醇-6’-O-α-吡喃木糖-O-β-吡喃葡萄弹苷(10)、肉桂醇-6’-O-α-呋喃阿拉伯糖基-O-β-吡喃葡萄弹苷(11)、肉桂醇-O-β-D-吡喃葡萄弹苷(12)、对-羟基-苯乙醇(13)、3,7-二甲基-2,6-二烯-1,4-二辛醇(14)、3,7-二甲基-2,6-二烯-1,4-二辛醇-O-β-吡喃葡萄糖苷(15)。其中化合物1～4为首次在玫瑰红景天发现。     

板蓝根中甙类成分的研究

从板蓝(Bophicacanthus cusia(Nees)Bremek．)根甲醇提取物的正丁醇萃取部分中分离鉴定了4个甙类成分,分别为(2r)-2-O-β-D-吡喃葡萄糖基-1,4-苯并噁嗪-3-酮(1)、(2R)-2-O-β-D-吡喃葡萄糖基-4-羟基-1,4-苯并噁嗪-3-酮(2)、松脂酚4-O-β-D-芹菜糖基-(1→2)-β-D-吡喃葡萄糖甙(3)和尿苷。这些化合物均为首次从板蓝根中发现。板蓝根中存在苯并噁嗪酮衍生物(1和2)可能与其消炎作用有关。     

辐状肋柱花的苷类成分

利用硅胶柱层析、Sephadex LH-20及反相硅胶RP-18分离及纯化技术,从辐状肋柱花全草乙醇提取物的正丁醇萃取部分得到7个水溶性成分,经1H NM R、13C NM R等波谱技术鉴定为异荭草苷、芒果苷、Sw ertipun i-cos ide、当药醇苷、异牡荆苷、当药黄素、和7-O-[α-L-吡喃鼠李糖-(1→2)-β-D-吡喃木糖]-1,8-二羟基-3-甲氧基口山酮.除异荭草苷外,其余化合物均首次从该植物中得到.     

New sesterterpenoids and other constituents from Salvia dominica growing wild in Jordan

A new nor-oleanane triterpene 24-nor-4(23)-12-oleanadien-2α,3α,28-triol (1) and two new sesterterpenes salvidominicolide A (2), salvidominicolide B (3) together with fifteen known compounds were isolated from Salvia dominica L. growing wild in Jordan. The known compounds comprised six flavones, three triterpenes, one diterpene, one sesterterpene, two oxygenated monoterpenes, one sterol glucoside and one flavone glucoside. The isolated compounds were elucidated by extensive spectroscopic methods including NMR (1D and 2D), UV, IR and MS (HRMS).     

Structurally Diverse Metabolites from the Marine-Derived Streptomyces sp. DS-27 Based on Two Different Culture Conditions

Nine new compounds, including streptothiomycin A−E ( 1 – 5 ), two cyclopentenones ( 6 , 7 ), one α-pyrone ( 8 ), wailupemycin Q ( 20 ), along with sixteen known compounds were identified from a rhizosphere strain Streptomyces sp. DS-27 derived from the marine cordgrass Spartina alterniflora under two different culture conditions. All of the structures were elucidated by extensive analysis of 1D/2D NMR and HR-ESI-MS data. The absolute configurations were determined by NOESY analysis, ECD, specific rotation and GIAO NMR calculations, and DP4+ probability analysis. Bioactivity investigation showed that compounds 5 and 7 exhibited significant inhibitory effects on LPS-induced NO production in a dose-dependent manner, which indicates their anti-inflammatory potential.     

A new neolignan glucoside from hairy roots of Cichorium intybus

A new neolignan glucoside was isolated from hairy roots of Cichorium intybus. Its structure was determined as (7S, 8R)-3′-demethyl-dehydrodiconiferyl alcohol-3′-O-β-glucopyranoside based on a combination of 1D and 2D NMR techniques and CD data. In addition, further water soluble constituents, including four known phenolic compounds and one known sesquiterpene lactone glucoside, were isolated from the same source.     

朝鲜蓟叶中的酚性糖苷化合物

从朝鲜蓟（Cynara scolymus）叶中分离得到2个酚性糖苷化合物,其中一个是新化合物,通过波谱学方法确定其结构为2-甲氧基-4-（2,3-二羟基-丙酰基）-苯基-1—O-（6′-O-没食子酰基）-β-D-吡喃葡萄糖苷（1）。     

Acylated flavonoids and phenol glycosides from Veronica thymoides subsp. pseudocinerea

A new acylated flavone glucoside, 3'-hydroxyscutellarein 7-O-(6'-O-protocatechuoyl)-beta-glucopyranoside (1), and a new phenol glucoside, 3,5-dihydroxyphenethyl alcohol 3-O-beta-glucopyranoside (6) were isolated from Veronica thymoides subsp. pseudocinerea together with seven known flavone, phenol and lignan glycosides; 3'-hydroxyscutellarein 7-O-(6'-O-trans-feruloyl)-beta-glucopyranoside (2), 3'-hydroxy, 6-O-methylscutellarein 7-O-beta-glucopyranoside (3), luteolin 7-O-beta-glucopyranoside (4), isoscutellarein 7-O-(6'-O-acetyl)-beta-allopyranosyl (1' --> 2')-beta-glucopyranoside (5), 3,4-dihydroxyphenethyl alcohol 8-O-beta-glucopyranoside (7), benzyl alcohol 7-O-beta-xylopyranosyl (1" --> 2')-beta-glucopyranoside (8), and (+)-syringaresinol 4'-O-beta-glucopyranoside (9). Compounds 2, 3 and 7-9 were reported for the first time in the genus Veronica. The structures of the isolates were determined by means of spectroscopic (UV, IR, 1D and 2D NMR, HR ESI-MS) methods. Isolated compounds (1-7) exhibited potent radical scavenging activity against the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.     

A new triterpene saponin from Chenopodium ficifolium

The new triterpene saponin 3-O-beta-D-glucopyranoside, 28-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosiduronic acid oleanolate was isolated from the roots of Chenopodium ficifolium. The known compounds stigmasterol-3-O-glucoside and 3-O-beta-D-glucopyranosiduronic acid, 28-beta-D-glucopyranosyl oleanolate were also isolated. The latter compound, oleanolic acid, beta-sitosterol and its glucoside were isolated from the aerial parts. The identity of these compounds was verified through different chemical and physico-chemical evidences including different 1D and 2D NMR experiments.     

Sesquiterpene Glucosides from Chloranthus japonicus Sieb

A new lindenane sesquiterpene glucoside named yinxiancaoside A (1), a new, rare bidesmosidic megastigmane sesquiterpene glucoside named yinxiancaoside B (5), and three known sesquiterpene glucosides, chloranoside A (2), pisumionoside (3), and sarcaglaboside A (4), were isolated from the whole plant of Chloranthus japonicus Sieb. The structures of the new compounds were established by an extensive study of their spectral data, especially 1D- and 2D-NMR. The cytotoxic activity of the isolated compounds against human hepatoma (Hepg-2), human ovarian carcinoma (OV420), and human breast cancer (MCF-7) cells was investigated.     

Glucosides from Vitex agnus-castus

The methanolic extract of the flowering stems of Vitex agnus-castus yielded three new iridoids: 6'-O-foliamenthoylmussaenosidic acid (agnucastoside A), 6'-O-(6,7-dihydrofoliamenthoyl)mussaenosidic acid (agnucastoside B) and 7-O-trans-p-coumaroyl-6'-O-trans-caffeoyl-8-epiloganic acid (agnucastoside C) in addition to four known iridoids (aucubin, agnuside, mussaenosidic acid and 6'-O-p-hydroxybenzoylmussaenosidic acid) and one known phenylbutanone glucoside (myzodendrone). The structure elucidations were mainly done by spectroscopic methods (1D and 2D NMR spectra) and MS data interpretation. The purified compounds were tested for biological activities against various microorganisms and cancer cell lines.     

α-pyrone derivatives from endophytic fungus Diaporthe sp. RJ-41

A new α-pyrone derivative 1 and six known α-pyrone derivatives 2–7, along with known compounds 8–10 were isolated from the fermentation products of the endophytic fungus Diaporthe sp. RJ-41. Among them, nine compounds (1–9) were reported for the first time from the genus Diaporthe. This work expanded the knowledge of the chemical diversity of the genus Diaporthe, and the chemotaxonomic significance of the isolates was also discussed.