库蠓的一个新种——蒙古库蠓

库蠓(Culicoides)属乃双翅目(Diptera),长角亚目(Nematocera),蠓科(Heleidae)中的一个属。库蠓在世界上的分布是非常广泛的,据Arnaud氏(1956)报告,库蠓已发现671种,仅在旧北区就有180种以上。 作者于1960年5月,从包头市采集到一种库蠓,经鉴定结果认为系一新种,并定名为蒙古库蠓(Culicoides mongolensis sp.nov.)。今将该种库蠓的形态详细记述如下。     

西藏库蠓和印度库蠓雄蠓的发现与描述(双翅目：蠓科)

西藏库蠓和印度库蠓雄蠓的发现与描述（双翅目：蠓科）翟逢伊（第二军医大学寄生虫学教研室上海２００４３３）王绪勇,邓成玉（成都军区军事医学研究所成都６１００６１）西藏库檬和印度库嫁的雄檬迄今尚无描述报道,作者在整理鉴定１９８９年采自西藏的螳类标本中发现上...     

毛蠓一新种和柱蠓一新纪录的记述(双翅目:蠓科)

2006年9月在法国南部佩皮里昂的马力布度假村发现马力布毛蠓新种Dasyhelea (Pseudoculicoides) malibui sp. nov.和尖突柱蠓Stilobezzia oxiana Remm,1980一新纪录,本文分别予以记述.     

中国柱蠓名录及柱蠓属一新种描述(双翅目,蠓科)

本文记述了中国已记载的柱蠓名录及其分布,并对采自贵州省荔波县茂兰国家级自然保护区内的柱蠓属一新种翁昂柱蠓Stilobezzia (Stilobezzia) wenganga Yu,Wu and Liu sp. nov.进行了描述.模式标本保存于北京医学昆虫标本馆.     

越南非吸血蠓类毛蠓属一新种（双翅目：蠓科）

毛蠓亚科已知有476种,广布世界各地。本描述的河内毛蠓新种Dasyhelea hanoiensis是越南河内市毛蠓新种的初次报导。模式标本收藏于医学昆虫标本馆(北京100071,丰台,东大街20号)。     

西藏的吸血蠓(双翅目:蠓科)

1973年至1976年,我所在参加中国登山队,和我院青藏高原综合科学考察队工作中,于西藏地区共采到吸血蠓3 属34 种,其中拉蠓属(Lasiohelea)1种,勒蠓属(Leptoconops)1新种,库蠓属(Culicoides)32种,包括6新种和国内新纪录7种。 模式标本均保藏于中国科学院动物研究所。     

云南省的库蠓(双翅目:蠓科)

1977年作者在云南省进行了吸血蠓种类的调查,共采得库蠓 Culicoides 30种,其中包括3个新种及4种我国新纪录。连同瞿逢伊等于1978年的报道,现云南省共计已有39种库蠓。即:蛮库蠓C.sacvus,抚库蠓 C.palpifer,金库蠓 C.flavescens,长囊库蠓C.longiporus,肩库蠓 C.humeralis,嗜按库蠓C.anophelis,趋黄库蠓 C.paraflavescens,勐腊库蠓 C.menglaensis,棕胸库蠓 C.macfiei,暗背库蠓 C.elbelei,倦库蠓 C.liui,缘斑库蠓 C.marginalis,异域库蠓 C.peregrinus,奄美库蠓 C.amamiensis,加库蠓 C.     

青岛埃蠓一新种(双翅目:蠓科)

埃蠓属１新种青岛埃蠓Ａｌｌｏｈｅｌｅａｑｉｎｇｄａｏｅｎｓｉｓｓｐ．ｎｏｖ１９８７年９月１０日于青岛市郊灯诱采得，模式标本收藏于军事医学科学院微生物流行病学研究所医学昆虫标本馆。     

两广的吸血蠓(双翅目:蠓科)

1973年我所在广东省和广西壮族自治区的许多地区,进行了吸血蠓采集工作。经整理共有2属,26种。其中,库蠓属(Culicoides)23种,包括2新种及1新纪录,拉蠓属(Lasiohelea)3种,包括1新种及1新纪录。新种模式标本均保藏于中国科学院北京动物研究所。     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

鸡传染性法氏囊病病毒研究进展

传染性法氏囊病(Infection bursal disease, IBD)是由鸡传染性法氏囊病毒(Infectious bursal disease virus, IBDV)引起的鸡和火鸡的一种高度接触性传染病,给世界各国的禽养殖业带来了巨大损失.自IBDV发现至今新的变异株不断出现,分子结构的改变导致病毒致病力的改变及宿主对疫苗应答的改变,使得传统的疫苗已不能控制其流行,因此各国学者对其基因组结构和功能进行了广泛深入的研究,并积极研制新型有效的疫苗以达到防治的目的.     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.