半枝莲中印黄芩甙的R－HPLC分析

半枝莲中印黄芩甙的Ｒ－ＨＰＬＣ分析代雪平魏波（河南省药检所,郑州４５０００３）（河南省人民医院药剂科,郑州４５０００３）Ｒ┐ＨＰＬＣａｎａｌｙｓｉｓｏｆｓｃｕｔｅｌａｒｉｎｆｒｏｍＳｃｕｔｅｌａｒｉａｂａｒｂａｔａＤ．ＤｏｎＤａｉＸｕｅ－Ｐｉｎｇ（Ｈ...     

滇东南假卫矛属一新种

麻栗坡假卫矛　新种　 (聚伞圆锥组 )ＭｉｃｒｏｔｒｏｐｉｓｍａｌｉｐｏｅｎｓｉｓＹ .Ｍ .Ｓｈｕｉ＆Ｗ .Ｈ .Ｃｈｅｎ ,ｓｐ .ｎｏｖ .　 [Ｓｅｃｔ.Ｃｙｍｏｓｏ ｐａｎｉｃｕｌａｔａ (Ｍｅｒｒ.ｅｔＦｒｅｅｍ .)Ｃ .Ｙ .ＣｈｅｎｇｅｔＴ .Ｃ .Ｋａｏ]ＳｐｅｃｉｅｓＭｉｃｒｏｔｒｏｐｉｓｓｃｏｔｉｉＰａｒｋｉｎｓａｒｃｔｅａｆｆｉｎｉｓ ,ｓｅｄｆｏｌｉｉｓ 19- 2 4ｃｍｌｏｎｇｉｓ ,ｃｙｍｉｓｑｕａｒｔｅｒｖｅｌｑｕｉｎｑｕｉｅｓｒａｍｏｓｉｓ ,ｓｅｐａｌｉｓｉｎｖｏｌｕｔｉｓ (ｎｅｃｒｅｖｏｌｕｔｉｓ)ｄｉｆ…     

广西唇柱苣苔属一新种

融安唇柱苣苔　新种　图 1ＣｈｉｒｉｔａｒｏｎｇａｎｅｎｓｉｓＤ .ＦａｎｇｅｔＹ .Ｇ .Ｗｅｉ,ｓｐ .ｎｏｖ .(Ｃｈｉｒｉｔａｓｅｃｔ.ＧｉｂｂｏｓａｃｃｕｓＣ .Ｂ .Ｃｌａｒｋｅ) .Ｆｉｇ .1ＨａｂｉｔｕｓｉｍｉｌｉｓＣ .ｇｅｍｅｌｌａｅＤ .Ｗｏｏｄ ,ｑｕａｅｒｈｉｚｏｍａｔｅｓｔｏｌｏｎｉｆｅｒｏ ,ｆｏｌｉｉｓｅｌｌｉｐｔｉｃｉｓｖｅｌｏｂｏｖａｔｉｓｍｉｎｏｒｉｂｕｓｉｎｔｅｇｒｉｓ,ｃｙｍｉｓ 1～ 4＿ｆｌｏｒｉｓ,ｃｏｒｏｌｌａｅｔｕｂｉｏｒｅ 1 7ｍｍｄｉａｍ .,ｓｔａｍｉｎｕｍｆｉｌａｍｅｎｔｉｓｓ…     

拔毒散中的蜕皮激素

ＴｈｅｇｅｎｕｓＳｉｄａｗｉｔｈａｂｏｕｔ 90ｓｐｅｃｉｅｓｉｓｄｉｓｔｒｉｂｕｔｅｄｗｉｄｅｌｙｉｎｔｈｅｔｅｍｐｅｒａｔｅｚｏｎｅｉｎｔｈｅｗｈｏｌｅｗｏｒｌｄ .Ｓｉｄａｓｚｅｃｈｕｅｎｓｉｓ,ｗｈｉｃｈｉｓａｐｅｒｅｎｎｉａｌ,ｈａｌｆ -ｓｈｒｕｂｆｏｕｎｄｔｈｒｏｕｇｈｏｕｔｔｈｅｈｉｇｈｌａｎｄｏｆｓｏｕｔｈ ｗｅｓｔｅｒｎＣｈｉｎａａｎｄａｂｕｎｄａｎｔｉｎｒｅｓｏｕｒｃｅｓ,ｉｓｏｎｅｏｆｓｐｅｃｉｅｓｏｆＭａｌｖａｃｅａｅ .ＩｔｉｓｕｓｅｄｉｎＣｈｉｎｅｓｅｔｒａｄｉ ｔｉｏｎａｌｍｅ…     

川东北二叠纪吴家坪期牙形石（刺）序列及其世界对比

对四川省宣汉县渡口和南江县桥亭吴家坪期地层的系统采集和研究结果表明,吴家坪期至少包括７个牙形石带,自下而上为Ｃｌａｒｋｉｎａｄｕｋｏｕｅｎｓｉｓ带,Ｃ．ａｓｙｍｍｅｔｒｉｃａ带,Ｃ．ｌｅｖｅｎｉ带,Ｃ．ｇｕａｎｙｕａｎｅｎｓｉｓ带,Ｃ．ｔｒａｎｓｃａｕｃａｓｉｃａ带,Ｃ．ｏｒｉｅｎｔａｌｉｓ和Ｃ．ｉｎｆｌｅｃｔａ带。其中,前３个带的层位低于一直作为吴家坪期早期的Ｃ．ｌｉａｎｇｓｈａｎｅｎｓｉｓ带。吴家坪阶的顶界以置于Ｃ．ｉｎｆｌｅｃｔａ带与Ｃ．ｓｕｂｃａｒｉｎａｔａ带之间较妥。同时,建立了Ｃｌａｒｋｉｎａｄｕｋｏｕｅｎｓｉｓ,Ｃ．ａｓｙｍｍｅｔｒｉｃａ,Ｃ．ｂｉｚａｒｒｅｎｓｉｓ,Ｃ．ｄａｘｉａｎｅｎｓｉｓ,Ｃ．ｄｅｍｉｃｏｒｎｉｓ,Ｃ．ｉｎｆｌｅｃｔａ,Ｃ．ｌｏｎｇｉｃｕｓｐｉｄａｔａ等７个新种。     

天然药物信息(医学期刊扫描:文摘和评论)(英文)

Ｂｅｔａ ＣａｒｏｔｅｎｅＳｕｐｐｌｅｍｅｎｔａｔｉｏｎＢｅｎｅｆｉｔｓＣｙｓｔｉｃＦｉｂｒｏｓｉｓＰａｔｉｅｎｔｓＲｕｓｔＰ ,ＥｉｃｈｌｅｒＩ ,ｅｔａｌ.Ｌｏｎｇ ｔｅｒｍｏｒａｌｂｅｔａ ｃａｒｏｔｅｎｅｓｕｐ ｐｌｅｍｅｎｔａｔｉｏｎｉｎｐａｔｉｅｎｔｓｗｉｔｈｃｙｓｔｉｃｆｉｂｒｏｓｉｓ.Ｅｆｆｅｃｔｓｏｎａｎｔｉｏｘ ｉｄａｔｉｖｅｓｔａｔｕｓａｎｄｐｕｌｍｏｎａｒｙｆｕｎｃｔｉｏｎ .ＡｎｎａｌｓｏｆＮｕｔｒｉｔｉｏｎａｎｄＭｅｔａｂｏｌｉｓｍ ,2 0 0 0 ;44 (1) :30～ 37.Ｐａｔｉｅｎｔｓｗｉｔ…     

天然药物信息(医学期刊扫描:文摘和评论)(英文)

Ｂｅｔａ ＣａｒｏｔｅｎｅＳｕｐｐｌｅｍｅｎｔａｔｉｏｎＢｅｎｅｆｉｔｓＣｙｓｔｉｃＦｉｂｒｏｓｉｓＰａｔｉｅｎｔｓＲｕｓｔＰ ,ＥｉｃｈｌｅｒＩ,ｅｔａｌ.Ｌｏｎｇ ｔｅｒｍｏｒａｌｂｅｔａ ｃａｒｏｔｅｎｅｓｕｐｐｌｅ ｍｅｎｔａｔｉｏｎｉｎｐａｔｉｅｎｔｓｗｉｔｈｃｙｓｔｉｃｆｉｂｒｏｓｉｓ.Ｅｆｆｅｃｔｓｏｎａｎｔｉｏｘｉｄａｔｉｖｅｓｔａ ｔｕｓａｎｄｐｕｌｍｏｎａｒｙｆｕｎｃｔｉｏｎ .ＡｎｎａｌｓｏｆＮｕｔｒｉｔｉｏｎａｎｄＭｅｔａｂｏｌｉｓｍ ,2 0 0 0 ;44 (1) :30～ 37.Ｐａｔｉｅｎｔｓｗｉｔ…     

中国大萼苔科一新记录属

钝叶苔属(Ｃｌａｄｏｐｏｄｉｅｌｌａ)隶属于苔类植物的大萼苔科(Ｃｅｐｈａｌｏｚｉａｃｅａｅ),本属有2种:Ｃ.ｆｌｕｉｔａｎｓ(Ｎｅｅｓ)Ｓｐｒ.和Ｃ.ｆｒａｎｃｉｓｃｉ(Ｈｏｏｋ.)Ｂｕｃｈ.,广泛分布于欧洲和北美洲,其中前者在日本有记录。本属我国首次记录,仅发现1种:Ｃ.ｆｒａｎｃｉｓｃｉ(Ｈｏｏｋ.)Ｂｕｃｈ.,分布西藏。钝叶苔属ＣｌａｄｏｐｏｄｉｅｌｌａＢｕｃｈ.,Ｍｅｍ.Ｓｏｃ.Ｆ.Ｆｌ.Ｆｅｎｎｉｃａ5:87,1927.Ｔｙｐｅ:Ｃｌａｄｏｐｏｄｉｅｌｌａｆｌｕｉｔａｎｓ(Ｎｅｅｓ)Ｓｐｒ.植物体纤细,淡绿色。茎具腹面分枝,横切…     

滇东南大围山地区远志科一新种

肉茎远志　新种　图 1ＰｏｌｙｇａｌａｃａｒｎｏｓｉｃａｕｌｉｓＷ .Ｈ .Ｃｈｅｎ＆Ｙ .Ｍ .Ｓｈｕｉ,ｓｐ .ｎｏｖ .Ｆｉｇ .1(Ｓｅｃｔ .ＰｓｅｕｄｏｓｅｎｅｉｏｃａｒｄｉｕｍＡｄｅｍａ)ＳｐｅｃｉｅｓＰ ｌａｃｅｉＣｒａｉｂｅｔＰ ｉｓｏｃａｒｐａｅＣｈｏｄａｔａｆｆｉｎｉｓ ,ｓｅｄｃａｕｌｅｃａｒｎｏｓｏ ,4 - 6ｍｍｄｉａｍ ,ｓｅｍｉｎｕｍｔｅｓｔｉｓｌａｅｖｉｂｕｓ ,ｐｕｎｃｔａｔｉｓｎｏｎｖｅｒｒｕｃａｔｉｓｄｉｆｆｅｒｔ.Ｈｅｒｂａａｎｎｕａ ,10 - 30ｃｍａｌｔａ .Ｒａｄｉｘｌｉｇｎｏｓａ .Ｃａｕ…     

Somatic cell cryopreservation and protoplast regeneration of important disease-resistant wild rice Oryza meyeriana Baill

Ｗｉｌｄｇｅｒｍｐｌａｓｍｃｏｎｓｉｓｔｓｏｆａｎｉｍｐｏｒｔａｎｔｂａｓｉｓｆｏｒｇｅｎｅｔｉｃｉｍｐｒｏｖｅｍｅｎｔｏｆｃｕｌｔｉｖａｔｅｄｒｉｃｅ.ＯｒｙｚａｍｅｙｅｒｉａｎａｉｓｏｎｅｏｆｔｈｅｔｈｒｅｅｗｉｌｄＯｒｙｚａｓｐｅｃｉｅｓｆｏｕｎｄｉｎＣｈｉｎａ[1].ＡｃｃｅｓｓｉｏｎｓｏｒｉｇｉｎａｔｅｄｉｎＹｕｎｎａｎＰｒｏｖｉｎｃｅｅｘｈｉｂｉｔｓｔｒｏｎｇｒｅｓｉｓｔａｎｃｅｔｏｂａｃｔｅｒｉａｌｌｅａｆｂｌｉｇｈｔ[2].Ｏ.ｍｅｙｅｒｉａｎａｇｒｏｗｓｏｎｔｈｅｈｉｌｌｓｉｄｅｕｎｄｅ…     

Phenylethanoid Glycosides from Picria felterrae Lour.

In our search for bioactive compounds from the whole plant of Picriafelterrae Lour., three new phenylethanoid glycosides, picfeosides A-C (1-3), along with five known phenylethanoid glycosides,namely wiedemannioside (4), acteoside (5), acteoside isomer (6), cis-acteoside isomer (7), and cis-acteoside (8), were isolated using several chromatographic purification steps, including semipreparation HPLC on RP-18. The structures of the new compounds were elucidated on the basis of extensive spectroscopic analysis.     

Phenylethanoid Glycosides from Picria felterrae Lour.

In our search for bioactive compounds from the whole plant of Picriafelterrae Lour., three new phenylethanoid glycosides, picfeosides A-C (1-3), along with five known phenylethanoid glycosides,namely wiedemannioside (4), acteoside (5), acteoside isomer (6), cis-acteoside isomer (7), and cis-acteoside (8), were isolated using several chromatographic purification steps, including semipreparation HPLC on RP-18. The structures of the new compounds were elucidated on the basis of extensive spectroscopic analysis.     

Dihydroisocoumarins and Phenylglycosides from Scorzonera longiana,Their Antimicrobial Activities and Molecular Docking Studies

Five new phenyl dihydroisocoumarin glycosides ( 1 – 5 ) and two known compounds ( 6 – 7 ) were identified from the butanol fraction of Scorzonera longiana. The structures of 1 – 7 were elucidated based on spectroscopic methods. Antimicrobial, antitubercular, and antifungal evaluation of compounds 1 – 7 were carried out using the microdilution method against nine microorganisms. Compound 1 was active only against Mycobacterium smegmatis (Ms) with a MIC value of 14.84 μg/mL. All tested compounds ( 1 – 7 ) were active against Ms but only compounds 3–7 were active against fungi (C. albicans, S. cerevisiae) with MIC values of 25.0–125 μg/mL. In addition, molecular docking studies were conducted against Ms DprE1 (PDB ID: 4F4Q), Mycobacterium tuberculosis (Mbt) DprE1 (PDB ID: 6HEZ), and arabinosyltransferase C (EmbC, PDB ID: 7BVE) enzymes. Compounds 2 , 5 , and 7 are the most effective Ms 4F4Q inhibitors. Compound 4 was the most promising inhibitory activity on Mbt DprE with the lowest binding energy of −9,9 kcal/mol.     

鼬瓣花中的黄酮苷

从鼬瓣花甲醇提取物中分离得到4个黄酮苷类化合物,运用光谱技术鉴定了它们的结构,分别为洋芹素-7-O-(6″-O-p-羟基肉桂酰)-β-D-吡喃葡萄糖苷(1),洋芹素-7-葡萄糖苷(2),木犀草素-7-葡萄糖苷(3)和黄芩苷(4)。化合物1为首次从鼬瓣花属植物中分离获得。     

水红木中两个新的酚苷成分

从水红木（Viburnum cylindricum）植物中分离出2个新化合物,1-phlomglucinyl-（6-methybutyryl）-β-D-glucopyranoside命名为cylindrin A（1）,1-[4-（3-hydroxyl-propyl）]-pyrocatechol-（6-methybutyryl）-β-D—glucopyranoside,命名为cylindrin B（2）。以及7个已知化合物tachioside（3）,syingic acid-4-β-D-glucopyran oside（4）,1-β-D—glucopyanosyloxy-3-methoxy-5-hydroxybenzene（5）,4-hydroxy-3-methoxyphenol-1-O-β-D-glucoside（6）,4-hydroxy-2,6-dimethoxyphen-1-O-β-D-glucoside（7）,phlorogluc inol-1-O-β-D-glucoside（8）,1-β-D-glucosyloxy-2-（3-nrethoxy-4-hydroxyphenyl）propane-1,3-diol（9）．它们的结构经波谱方法得到鉴定。3—9为首次从该种植物中分离得到。     

Three New Flavone Glycosides from Drymaria diandra Bl.

In order to find new structural and biologically active compounds, the constituents from the whole plant of Drymaria diandra B1. (Caryophyllaceae) were investigated and three new flavone glycosides,named drymariatins B (1), C (2), and D (3), were isolated by solvent partition, Si gel, sephadex LH-20, and Rp-18 column chromatography. Using spectroscopic methods, including two-dimensional nuclear magnetic resonance analysis, the structures of these compounds were elucidated as 6-C-(2-deoxy-β-D-fucopyranosyl)-5,7,4'-trihydroxyl-flavone, 6-C-(2-deoxy-β-D-fucopyranosyl)-7-O-(β-D-glucopyranosyl)-5,4'-dihydroxylflavone, and 6-C-(3-keto-β-digitoxopyranosyl)-7-O-(β-D-glucopyranosyl)-5,4'-dihydroxyl-flavone.     

Iridoid glycosides and cucurbitacin glycoside from Neopicrorhiza scrophulariiflora

Three iridoid glycosides, picrorosides A (1), B (2) and C (3), and a cucurbitacin glycoside, scrophoside A (4), were isolated from the rhizomes of Neopicrorhiza scrophulariiflora (Scrophulariaceae), along with two known iridoid glycosides, picrosides I (5) and II (6), and three known cucurbitacin glycosides (7-9). Their structures were elucidated on the basis of both chemical and spectroscopic data.     

Three New Flavone Glycosides from Drymaria diandra B1.

In order to find new structural and biologically active compounds, the constituents from the whole plant of Drymaria diandra B1. （Caryophyllaceae） were investigated and three new flavone glycosides, named drymariatins B （1）, C （2）, and D （3）, were isolated by solvent partition, Si gel, sephadex LH-20, and Rp- 18 column chromatography. Using spectroscopic methods, including two-dimensional nuclear magnetic resonance analysis, the structures of these compounds were elucidated as 6-C-（2-deoxy-β-D-fucopyranosyl）- 5,7,4＇-trihydroxyl-flavone, 6-C-（2-deoxy-β-D-fucopyranosyl）-7-O-（β-D-glucopyranosyl）-5,4＇-dibydroxyl- flavone, and 6-C-（3-keto-β-digitoxopyranosyl）-7-O-（β-D-glucopyranosyl）-5,4＇-dihydroxyl-flavone.     

Two New Phenolic Glycosides from Viburnum cylindricum ( Caprifoliaceae)

从水红木( Viburnum cylindricum ) 植物中分离出2 个新化合物, 1- phloroglucinyl- ( 6-methybutyryl )-B-D- glucopyranoside命名为cylindrin A ( 1) , 1- [ 4- ( 3- hydroxy-l propyl ) ]- pyrocatechol- ( 6-methybutyryl )-B-D- glucopyranoside, 命名为cylindrin B ( 2) , 以及7 个已知化合物tachioside ( 3) , syingic acid-4-B-D- glucopyran oside ( 4) , 1-B-D-glucopyranosyloxy-3-methoxy-5- hydroxybenzene ( 5 ) , 4- hydroxy- 3-methoxypheno-l 1-O-B-D- glucoside ( 6 ) , 4-hydroxy- 2, 6- dimethoxypheno-
l 1-O-B-D- glucoside ( 7) , phlorogluc ino-l 1-O-B-D-glucoside ( 8 ) , 1-B-D- glucosyloxy-2- ( 3-methoxy- 4- hydroxyphenyl) propane- 1, 3- diol ( 9) . 它们的结构经波谱方法得到鉴定。3~ 9 为首次从该种植物中分离得到。     

Steroid glycosides and phenols from the roots of Cynanchum saccatum

A series of steroidal glycosides, including three new compounds, named saccatols A–C (1–3), and two known analogues (4–5), and eight phenols (6–13) were isolated from the roots of Cynanchum saccatum W.T. Wang ex Tsiang et P. T. Their structures were elucidated by interpretation of their spectral data, mainly HRESIMS, 1D and 2D NMR, and comparison with the literature data.