|
|||||
|
|
AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation |
|
| Authors: | R Jackstadt P Jung H Hermeking |
| Institution: | 1.Experimental and Molecular Pathology, Institute of Pathology, Ludwig-Maximilians-Universität München, Thalkirchner Strasse 36, D-80337 Munich, Germany;2.IRB/Institute for Research in Biomedicine, Parc Científic de Barcelona, C/Baldiri Reixac 10, 08028 Barcelona, Spain;3.German Cancer Consortium (DKTK), D-69120 Heidelberg, Germany;4.German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany |
| Abstract: | |
| Keywords: | AP4 c-MYC oncogene p16 tumor suppressor p21 senescence transformation cancer |