| 依赖端粒酶的端粒维持机制 |
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| 引用本文： | 林坚,黄君健,黄翠芬.依赖端粒酶的端粒维持机制[J].生物技术通讯,2004,15(3):278-280. |
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| 作者姓名： | 林坚 黄君健 黄翠芬 |
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| 作者单位： | 军事医学科学院生物工程研究所,北京,100850 |
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| 摘 要： | 端粒是真核生物染色体的末端重要结构复合物，对维持染色体稳定性起着重要作用。端粒酶的主要功能是复制端粒末端DNA，维持端粒长度。端粒酶活性调节与肿瘤发生和细胞衰老有着密切关系。本简要综述近年来依赖端粒酶的端粒维持机理的研究进展。
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| 关 键 词： | 端粒酶 真核生物 染色体 DNA 肿瘤 细胞衰老 |
| 文章编号： | 1009-0002(2004)03-0278-03 |
| 修稿时间： | 2003年12月26 |
Mechanism of telomere maintenance dependent on telomerase |
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| LIN Jian,HUANG Jun-jian,HUANG Cui-fen Institute of Biotechnology,Academy of Military Medical Sciences,Beijing,China.Mechanism of telomere maintenance dependent on telomerase[J].Letters in Biotechnology,2004,15(3):278-280. |
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| Authors: | LIN Jian HUANG Jun-jian HUANG Cui-fen Institute of Biotechnology Academy of Military Medical Sciences Beijing China |
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| Institution: | LIN Jian,HUANG Jun-jian,HUANG Cui-fen Institute of Biotechnology,Academy of Military Medical Sciences,Beijing100850,China |
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| Abstract: | Telomere is the function complex of eukaryotic chromosome,which is important to maintain the stability of chromosomes.The main function of telomerase is for the replication of telomere DNA,which is closely related with tumor and cell senescence.The research progress in telomere and telomerase in recent years is reviewed briefly in this article. |
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| Keywords: | telomere telomerase |
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