正交试验法优选伴抗宁口服液的闪式提取工艺

目的优选伴抗宁口服液的闪式提取工艺。方法采用正交试验法,以苯酚-硫酸比色法测定总多糖的含量为评价指标。采用闪式提取法提取中药材。结果伴抗宁口服液的最佳闪式提取工艺条件为药材用12倍量的水浸泡3 h,提取时间为1 m in,提取电压180 V。供试品平均回收率为99.27%（n=5）,RSD%为1.37。结论伴抗宁口服液的提取工艺方法经济、简单、稳定,可行质量可控。

Optimization of the flash extract technology of Bankangning oral liquid by orthogonal design method

Objective To optimize the flash extract technology of Bankangning oral liquid.Method An orthogonal design was applied. Content of polysaccharide determined by Phenol-sulfuric method was used as the marker of detection.Result The optimum process for flash extract technology of Bankangning oral liquid were as follows: the medicinal materials was soaked for 3 h with 12 folds amount of water and extracted by flash extractor for 1 min at the voltage of 180 V. The average recovery rate of polysaccharide was 99.27% with RSD of 1.37% (n=5). Conclusion The optimum technology of Bankangning oral liquid is simple, cost-effective, stable and efficient with the quality being controllable.