| 地高辛标记探针检测生物制品中残余DNA含量 |
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| 引用本文： | 李玉,姚伟,张岩锐,王跃.地高辛标记探针检测生物制品中残余DNA含量[J].微生物学免疫学进展,2002,30(4):23-25. |
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| 作者姓名： | 李玉 姚伟 张岩锐 王跃 |
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| 作者单位： | 兰州生物制品研究所,兰州,730046 |
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| 摘 要： | 用地高辛标记探针检测由传代细胞系生产的人用精制狂犬病疫苗，重组（CHO细胞）乙肝疫苗，出血热疫苗及痢疾多糖结合疫苗原液中残余DNA含量。结果表明，该方法特异性强，灵敏度高，可用于上述生物制品中残余DNA含量的检测。
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| 关 键 词： | 地高辛标记探针 检测 生物制品 残余DNA含量 |
| 文章编号： | 1005-5673(2002)-04-0023-03 |
| 修稿时间： | 2002年5月22日 |
The detection of the residual DNA in the biological products by labeled probe of digoxigenin |
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| LI Yu,YAO Wei,ZHANG Yan-rui,et al..The detection of the residual DNA in the biological products by labeled probe of digoxigenin[J].Progress In Microbiology and Immunology,2002,30(4):23-25. |
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| Authors: | LI Yu YAO Wei ZHANG Yan-rui |
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| Abstract: | The residual DNA in purified rabies vaccine, hepatitis B vaccine made by recombinant DNA techniques in CHO cell, Heamorrhagic Fever with Renal Syndrome (HFRS) vaccine and shigella polysaccharide vaccine were detected by labeled probe of digoxigenin.The results showed that the method has a high sensitivity and specificity.It is suitable for the detection of residual DNA in the biological products. |
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| Keywords: | Labeled Probe of digoxigenin Residual DNA Biological products |
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