| 实验恒河猴糖尿病动物模型建立及视网膜并发症的研究 |
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| 引用本文： | 代解杰,孙晓梅,匡德宣,高家红,唐东红,叶尤松,仝品芬,江勤芳.实验恒河猴糖尿病动物模型建立及视网膜并发症的研究[J].中国实验动物学报,2005(Z1). |
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| 作者姓名： | 代解杰 孙晓梅 匡德宣 高家红 唐东红 叶尤松 仝品芬 江勤芳 |
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| 作者单位： | 中国医学科学院/中国协和医科大学医学生物学研究所 昆明560118
(代解杰，孙晓梅，匡德宣，高家红，唐东红，叶尤松，仝品芬)，中国医学科学院/中国协和医科大学医学生物学研究所 昆明560118(江勤芳) |
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| 摘 要： | 目的]糖尿病是由于多种因素和遗传因素导致体内胰岛素相对或绝对分泌不足,而引起的代谢性内分泌疾病,它以血糖、尿糖升高为特点,起病隐蔽,通过并发症使人致残致死,是继心血管、癌症之后的第三大致死性疾病,很可能成为21世纪人类的“第一杀手”(1,2)。本文采用人工诱导的方法,建立恒河猴糖尿病动物模型,研究糖尿病疾病的发展和及其并发症的发生、发展规律和防治措施,同时对于治疗糖尿病新药的安全性评价和药物疗效的观察具有广阔的运用前景。方法]选用成熟的、健康的、雄性恒河猴9只,随机分成三个组,其中高剂量组(60mg/kg)1只,中剂量组(45m…
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Preliminary study on establishment of diabetes mellitus animal model and diabetic retinopathy in rhesus monkeys |
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| DAI Jie-jie,SUN Xiao-mei,KUANG De-xuan,GAO Jia-hong,TANG Dong-hong,YE You-song,TONG Ping-fen,JIANG Qin-fang Institute of Medical Biology,Chinese Academy of Medical Sciences/Peking Union Medical College,Kunming ,China.Preliminary study on establishment of diabetes mellitus animal model and diabetic retinopathy in rhesus monkeys[J].Acta Laboratorium Animalis Scientia Sinica,2005(Z1). |
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| Authors: | DAI Jie-jie SUN Xiao-mei KUANG De-xuan GAO Jia-hong TANG Dong-hong YE You-song TONG Ping-fen JIANG Qin-fang Institute of Medical Biology Chinese Academy of Medical Sciences/Peking Union Medical College Kunming China |
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| Institution: | DAI Jie-jie,SUN Xiao-mei,KUANG De-xuan,GAO Jia-hong,TANG Dong-hong,YE You-song,TONG Ping-fen,JIANG Qin-fang Institute of Medical Biology,Chinese Academy of Medical Sciences/Peking Union Medical College,Kunming 650118,China |
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| Abstract: | |
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| Keywords: | Rhesus monkeys Diabetes mellitus animal model Diabetic retinopathy |
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