| 丹皮多糖对α-葡萄糖苷酶作用的影响 |
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| 引用本文： | 戴玲,赵帜平,沈业寿,李剑峰,李明珠.丹皮多糖对α-葡萄糖苷酶作用的影响[J].生物学杂志,2006,23(2):23-24,38. |
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| 作者姓名： | 戴玲 赵帜平 沈业寿 李剑峰 李明珠 |
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| 作者单位： | 安徽大学生命科学学院,合肥,230039 |
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| 基金项目： | 安徽省自然科学基金资助项目(03043301) |
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| 摘 要： | 研究丹皮多糖(PSM2b)对α-葡萄糖苷酶作用的影响,探索其降血糖作用的途径。通过建立体外酶-抑制剂模型,测定丹皮多糖PSM2b及其分级分离组分对酶作用的抑制率。结果显示PSM2b的分级分离组分PSM2b-1,PSM2b-2,PSM2b-3在体外对α-葡萄糖苷酶有一定的抑制作用,PSM2b对酶的抑制作用不明显。
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| 关 键 词： | α-葡萄糖苷酶抑制剂 丹皮多糖 |
| 文章编号： | 1008-9632（2006）02-0023-02 |
| 收稿时间： | 2005-09-02 |
| 修稿时间： | 2005-09-02 |
Inhibition effect of components of PSM2b on α- glucosidase |
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| DAI Ling,ZHAO Zhi-ping,SHEN Ye-shou,LI Jian-feng,LI Ming-zhu.Inhibition effect of components of PSM2b on α- glucosidase[J].Journal of Biology,2006,23(2):23-24,38. |
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| Authors: | DAI Ling ZHAO Zhi-ping SHEN Ye-shou LI Jian-feng LI Ming-zhu |
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| Institution: | College of Life Sciences, Anhui University, Hefei 230039, China |
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| Abstract: | Polysaccharide PSM2b was extracted from Chinese herb Mudan cortex. To investigate the effects of polysaccharide PSM2b and its fractionations on alpha - glucosidase, enzyme - inhibitor assay was performed. The fractionations of PSM2b, PSM2b-1 ,PSM2b-2 ,PSM2b-3 were obtained by gel filtration chromatography. All of them exhibited alpha -glucosidase inhibitory activity to some extent, but PSM2b itself has no obvious inhibitory effect. |
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