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大火草根部的化学成分
引用本文:彭树林,王明奎,丁立生,王俊儒,冯俊涛.大火草根部的化学成分[J].Acta Botanica Sinica,1999(1).
作者姓名:彭树林  王明奎  丁立生  王俊儒  冯俊涛
基金项目:中国科学院成都地奥科学基金
摘    要:大火草(Anemone tomentosaa(Maxim.)Pei)根状茎提取物的乙酸乙酯部分对粘虫(LeucaniaseparataWalker)有较好的非选择性拒食活性。从该部分分离得到11个化合物,通过NMR、MS等波谱分析确定它们的结构分别为4,5-二甲氧基-7-甲基香豆素(1)、4-甲氧基-5-甲基-6,7-二氧亚甲基香豆素(2)、4,7-二甲氧基-5-甲基香豆素(3)、齐墩果酸(4)、齐墩果酮酸(5)、齐墩果酸-3-O-β-D-吡喃木糖甙(6)、β-谷甾醇(7)、豆甾醇(8)、胡萝卜甙(9)、豆甾醇-3-O-β-D-吡喃葡萄糖甙(10)和过氧化麦角甾醇(11)。这些化学成分均为首次从该植物中分离得到,其中1和2为新化合物。

关 键 词:大火草  拒食活性  4  5-二甲氧基-7-甲基香豆素  4-甲氧基-5-甲基-6  7-二氧亚甲基香豆素

Chemical Constituents of the Anemone tomentosa Root
Authors:WANG Jun-Ru  PENG Shu-Lin  WANG Ming-Kui  FNG Jun-Tao  DING Li-Sheng
Abstract:The roots of Anemone tomentosa (Maxim. ) Pei (Ranunculaceae) have been used as traditional medicine for the treatment of dysentery, infantile malnutrition, carbuncles, etc. Ethyl acetate extract of the roots displaied stronger antifeedant activity against Leucania separata Walker. Eleven compounds were isolated by silica gel columm chromatography from the extract and their structures were identified as 4,5-dimethoxyl-7-methyl-coumarin (1 ), 4-methoxyl-5(methyl-6, 7 - methylenedioxy- coulnarin (2 ), 4, 7 - dimethoxyl- 5 - methylcotnnarin (3), oleanolic arid (4), oleanonic acid (5), 3--O-5-D-xylopyranosyl oleanolic acid (6), -sitosterol (7), stigmaSterol (8), daucosterol (9), 3 - O-5- D- glucopystigmasterol (10 ) and egrterol pemtide (11) respectively on the baSis of special evidence. Compounds 1 and 2 are new naed products.
Keywords:Anemone tomentosa  Antifeedant activity  4  5 - dimethoxyl- 7 - methyl- coumarin  4 - methoxyl- 5 methyl-6  7 - methylenedioxy- coumarin
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