不同地区浅部真菌病病原菌流行状况比较

目的了解近半年来华东、华南、华北地区浅部真菌病病原菌的种类、构成情况以及菌种变迁。方法以近半年来在上海、广州、北京3家教学医院皮肤科就诊的浅部真菌病患者为3个地区的代表,对具有典型浅部真菌病临床表现且真菌镜检阳性的患者进行致病真菌的分离培养。结果共分离出致病真菌926株,其中红色毛癣菌544株（58.7%）,念珠菌132株（14.3%）,犬小孢子菌119株（12.9%）,须癣毛癣菌23株（2.5%）,石膏小孢子菌16株（1.7%）。华东地区浅部真菌构成比复杂,华南及华北地区相对简单。结论不同地区浅部致病真菌菌种及构成比存在差异;三地红色毛癣菌均仍占优势;而念珠菌和犬小孢子菌所占比例有上升趋势。

Causative agents of superficial mycosis in different geographical areas in China: an epidemiological survey

Objective To investigate the epidemic distribution of pathogenic fungi of superficial mycosis in the east, south and north areas of China in the recent half year. Methods Pathogenic fungi isolated from patients with clinical suspected superficial myeosis and positive microscopic examination results in three teaching hospital in Guangzhou Shanghai and Beijing were cultured. Resuits Nine hundred and twenty-six isolates were obtained in total, including 544 isolates of Trichophyton rubrum （58.7%）, 132 isolates of Candida （14.3%）, 119 isolates of Microsporum cants （12.9%）,23 isolates of T. mentagrophytes （2.5%） and 16 isolates of M. gypseum （ 1.7% ）. The composition ratio of superficial fungi in the east area of China is complex, and relatively simple in the south and north. Conclusions Causative agents of superficial mycosis are variable in different geographical areas. However, T. rubrum remains dominant in all of the three areas. The ratio of Candida and M. cants showed an increasing tendency.