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| DICE：电压门控离子通道电生理实验数据库 | |
| 引用本文： | 郭景康,梁茜,王超,李泽,张国庆,李亦学,孙晓明,王健.DICE：电压门控离子通道电生理实验数据库[J].生物信息学,2009,7(1):68-71. |
| 作者姓名： | 郭景康 梁茜 王超 李泽 张国庆 李亦学 孙晓明 王健 |
| 作者单位： | 1. 上海大学生命科学学院,上海,200444 2. 上海生物信息技术研究中心,上海,200233 3. 上海市普陀区食品药品监督所,上海,200333 |
| 基金项目： | 国家高技术研究发展计划(863计划) |
| 摘 要： | 针对现有相关文献中离子通道电生理数据繁多且分散的特点，开发了一套电压门控离子通道电生理实验数据库。数据库中目前主要包括钠离子通道序列数据、调制剂分子结构和序列数据，并收集整理了文献中调制剂和通道相互作用时的电生理学数据和药理学数据。系统实现了数据的收集、录入、存储和查询，为后期进行数据挖掘奠定了基础。用户可以通过网址http：／／biodb．sgst．cn／DICE对数据库进行访问。 |
| 关 键 词： | 电压门控离子通道 神经毒素 离子通道调制剂 电生理 |
DICE:Database of Ion Channel Electrophysiology |
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| GUO Jing-kang,LIANG Qian,WANG Chao,LI Ze,ZHANG Guo-qing,LI Yi-xue,SUN Xiao-ming,WANG Jian.DICE:Database of Ion Channel Electrophysiology[J].China Journal of Bioinformation,2009,7(1):68-71. | |
| Authors: | GUO Jing-kang LIANG Qian WANG Chao LI Ze ZHANG Guo-qing LI Yi-xue SUN Xiao-ming WANG Jian |
| Institution: | 1. School of Life Sciences, Shanghai University, Shanghai 200444, China; 2. Shanghai Center for Bioinformation Technology, Shanghai 200233, China;3. Shanghai Food and Drag Administration Putuo District Office, Shanghai 200333, China) |
| Abstract: | DICE （Database of Ion Channel Electrophysiology） is a database developed to hold electrophysiological and pharmacological data of interactions between ion channels and their modulators. These data were historically scattered among literatures and hard to mine. DICE collected and integrated the electrophysiological and pharmacological data, together with sequence and structure information of individual ion channels and modulators. DICE provides data submission, storage, query and download to facilitate further data integration and data mining. DICE can be accessed through the following website： http：//biodb, sgst. cn/DICE. |
| Keywords: | voltage - gated ion channels neurotoxins ion channel modulator electrophysiology |
| 本文献已被 维普 万方数据 等数据库收录！ | |