儿童过敏性结膜炎与变应性鼻炎的相关性及鼻眼联合防治效果分析

目的：探讨儿童过敏性结膜炎与变应性鼻炎的相关性研究及鼻眼联合防治的临床效果。方法：回顾性分析300 例儿童过敏性 结膜炎与310 例儿童变应性鼻炎患者的临床资料，对儿童过敏性结膜炎与变应性鼻炎的相关性进行分析后将所有患儿随机均分 为对照组与观察组，对照组采用常规点眼的方法进行治疗，观察组则采用鼻朗喷鼻联合人工泪液点眼进行治疗。比较两组临床疗 效及不良反应情况。结果：（1）300 例过敏性结膜炎患儿中，50 例（16.67%）并发变应性鼻炎；310 例变应性鼻炎患儿中，59 例 （19.03%）并发过敏性结膜炎（P＞0.05）；（2）109 例同时并发两种疾病患儿中，均进行眼结膜与鼻粘膜的刮片检查嗜酸性粒细胞， 其中60 例（55.05%）结膜刮片与67 例（61.47%）鼻粘膜刮片检测到嗜酸性粒细胞（P＞0.05）；（3）两组治疗前后BUT 及角膜荧光素 染色评分、症状评分、临床总有效率比较差异明显（P＜0.05）。结论：儿童过敏性结膜炎与变应性鼻炎具有一定的相关性；鼻朗喷鼻 联合人工泪液点眼治疗儿童合并变应性鼻炎的临床疗效显著。

The Research of Allergic Conjunctivitis in Children with Allergic Rhinitis and Nasal Eye Joint Prevention and Control of the Clinical Effect of Analysis

Objective:To study the correlation of children allergic conjunctivitis with allergic rhinitis and the clinical effect of nasal-eye joint prevention and cure.Methods:We retrospectively analyzed the clinic data of 300 cases of children with allergic conjunctivitis and 310 cases of children with allergic rhinitis. We firstly analyzed the correlation of allergic conjunctivitis with allergic rhinitis. All the patients were randomly divided into control group and observation group. The control group adopted the method of routine eye treatment, and the observation group got the Bright Nose nasal spray combined with artificial tears treatment. Compare the clinical curative effect and adverse reactions between the two groups.Results:(1) Of 300 cases allergic conjunctivitis, 50 cases (16.67%) complicated with allergic rhinitis. Of 310 cases of allergic rhinitis, 59 patients (19.03%) complicated with allergic conjunctivitis (P>0.05). (2) The 109 cases complicated with two diseases at the same time all had scraping smear detection of conjunctiva and nasal mucosa, and Eosinophils were detected in 60 cases (55.05%) of conjunctival smears blade and 67 cases (61.47%) of nasal mucosa smears blade (P > 0.05). (3) The total effective rate was in control group, significantly lower than the observation group (P<0.05). The symptom scores in the two groups before and after treatment, BUT and corneal fluorescein staining scores were statistically significant different (P<0.05, P<0.01) but after treatment the differences of the above index were statistically significant between the two groups (P<0.05).Conclusion:Allergic conjunctivitis in children with allergic rhinitis has certain relevance. The Bright Nose nasal spay combined artificial tears eye treatment had distinct clinical curative effect on allergic conjunctivitis children with allergic rhinitis.