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重症监护病房呼吸机相关性肺炎病原学以及耐药性分析
引用本文:陈中俊,彭易根,石岩,刘刚,韩秋,杜叶平.重症监护病房呼吸机相关性肺炎病原学以及耐药性分析[J].现代生物医学进展,2012,12(6):1118-1121.
作者姓名:陈中俊  彭易根  石岩  刘刚  韩秋  杜叶平
作者单位:江苏省淮安市第二人民医院重症医学科;江苏省淮安市第一人民医院骨科
摘    要:目的:探讨重症监护病房呼吸机相关性肺炎病原学以及耐药性。方法:对我院2007年2月-2011年7月ICU内出现呼吸机相关性肺炎的患者99例作为研究对象,并对取痰液标本进行病原学以及耐药性分析。结果:革兰阴性菌的检出明显高于其他菌属,在G-杆菌中铜绿假单胞菌以及大肠埃希菌最为常见,G+球菌中以金黄色葡萄球菌以及肺炎链球菌最为常见;所有菌属均对常规抗菌药物有一定的耐药性,但其对万古霉素的敏感性仍然较高。结论:加强对ICU呼吸机相关肺炎进行分离致病菌并对其进行耐药性检测,以指导合理使用抗菌药物,有助于改善患者预后。

关 键 词:重症监护室  呼吸机  肺炎  耐药性

Intensive Care Unit Ventilator-Associated Pneumonia Etiology, and Drug Resistance
CHEN Zhong-jun,PENG Yi-gen,SHI Yan,LIU Gang,HAN Qiu,DU Ye-ping.Intensive Care Unit Ventilator-Associated Pneumonia Etiology, and Drug Resistance[J].Progress in Modern Biomedicine,2012,12(6):1118-1121.
Authors:CHEN Zhong-jun  PENG Yi-gen  SHI Yan  LIU Gang  HAN Qiu  DU Ye-ping
Institution:1(1 intensive medicine of Huai’an Second People’s Hospital,Jiangsu province,223002; 2 Orthopaedics of Huai’an First People’s Hospital,Jiangsu province,223300)
Abstract:Objective: To investigate the intensive care unit ventilator-associated pneumonia etiology,and drug resistance.Methods: The hospital in February 2007 July 2011 appear in ICU ventilator-associated pneumonia in patients with 99 cases for the study,and spu-tum specimens of the etiology and to take drug resistance.Results: The detection of Gram-negative bacteria was significantly higher than other species,the G-bacteria Pseudomonas aeruginosa and Escherichia coli is the most common,G+cocci Staphylococcus aureus and Streptococcus pneumoniae is the most common;all species are on conventional antibiotics have some resistance,but its sensitivity to vancomycin remains high.Conclusion: To strengthen the ICU ventilator-associated pneumonia pathogens were isolated and its resistance testing to guide the rational use of antibiotics,help to improve the prognosis of patients.
Keywords:Intensive care unit  Ventilator  Pneumonia  Resistance
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