急性胰腺炎伴脾脏密度减低的研究现状

急性胰腺炎是临床上较常见的急腹症,以急性上腹痛和血尿淀粉酶或脂肪酶升高为其主要的临床特点,急性胰腺炎除了对胰腺自身组织的产生损伤外,对胰腺外器官也会产生不同的损伤,并引起一系列的并发症。在急性胰腺炎的脾脏并发症中,脾梗死在CT图像中表现为脾脏密度不均匀性减低,除此之外脾脏实质的密度在CT图像中是相对比较固定的,但是在有些急性胰腺炎患者的CT图像中会出现脾脏密度一过性弥漫性减低的影像表现,治疗后复查CT显示脾脏密度恢复正常,该现象的形成原因尚不清楚,国内外有关该现象的文献报道及研究十分的有限,本文通过分析急性胰腺炎的病因及发病机制,回顾相关的文献病例,探讨急性胰腺炎伴脾脏密度一过性弥漫性减低产生的可能性原因。

A Preliminary Study on the Transient Reduction of Spleen Density in Acute Pancreatitis

ABSTRACT: Acute pancreatitis is a common acute abdominal disease on clinic, and the major clinical characteristics of acute pan- creatitis are acute abdominal pain and the increased amylase or lipase in blood and urine. In acute pancreatitis extrapancreatic organs also produce different injury in addition to pancreatic tissue damage, at the same time causes a series of complications. In the complication of the spleen of acute pancreatitis, the density of spleen parenchyma is stable relatively except spleen infarction which shows heterogeneity decreased density of spleen on the CT images. However, sometimes we found an interesting phenomenon that is transient reduction of spleen density in patients with acute pancreatitis on the CT images of some patients with acute pancreatitis, and after treatment the reex- amination of CT shows that the density of spleen can be restored. The formation mechanism of this phenomenon is unclear, and litera- tures and research with respect to this phenomenon are very limited at home and abroad. In this paper, we explore the possibility reasons of the transient of spleen density in acute pancreatitis by analyzing the etiology and pathogenesis of acute pancreatitis, and reviewing the relevant literature.