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iCare眼压计测量小鼠眼压值与真实眼压的相关性研究
引用本文:环梦佳,袁志兰,袁松涛,钱朝旭,罗莎莎.iCare眼压计测量小鼠眼压值与真实眼压的相关性研究[J].现代生物医学进展,2011,11(16):3022-3024.
作者姓名:环梦佳  袁志兰  袁松涛  钱朝旭  罗莎莎
作者单位:1. 南京医科大学 江苏南京 210029
2. 江苏省人民医院 江苏南京 210029
3. 南京医科大学附属第一人民医院 江苏南京 210029
摘    要:目的:通过前房插管技术调节小鼠眼压,研究iCare眼压计测量小鼠眼压值与小鼠真实眼压之间的相关性。方法:取20只12周龄的C57BL/6J小鼠,麻醉后行前房穿刺置管,通过改变BSS液瓶高度调节其眼压。使用iCare眼压计测量其眼压值。采用SPSS软件分析iCare眼压计测量值和小鼠真实眼压之间的相关性。结果:iCare眼压计测量值与真实眼压之间相差较大,较真实眼压低约54%-71%,然而两者之间遵循如下线性回归方程:真实眼压(mmHg)=3.3988×(iCare眼压计测量值)-5.6292,rZ=0.9506,P<0.05。结论:iCare眼压计测量值较小鼠真实眼压低,然而在应用线性回归公式的情况下,iCare眼压计的测量修正值可以反映小鼠实际眼压值。

关 键 词:iCare眼压计  眼压  小鼠  相关性

Correlation Analysis of IOP Obtained from Mice Eyes with iCare Rebound Tonometer and True IOP
HUAN Meng-jia,YUAN Zhi-lan,YUAN Song-tao,QIAN Chao-xu,LUO Sha-sha.Correlation Analysis of IOP Obtained from Mice Eyes with iCare Rebound Tonometer and True IOP[J].Progress in Modern Biomedicine,2011,11(16):3022-3024.
Authors:HUAN Meng-jia  YUAN Zhi-lan  YUAN Song-tao  QIAN Chao-xu  LUO Sha-sha
Institution:1 Nanjing Medical University,210029,Nanjing,China;2 Jiangsu Province Hospital,Nanjing,210029 3 The First Affiliated Hospital With Nanjing Medical University,210029,Nanjing,China)
Abstract:Objective:To study the correlation between the IOP obtained from mice eyes with iCare tonometer and the true IOP. Methords:The IOPs of 20 healthy C57BL/6J mice were measured with a pressure transducer system which was connected to the anterior chamber so that the IOP could be varied by altering the height of a bottle of balanced salt solution.Intraocular pressures were recorded over a range of 10 to 50 mmHg by the transducer system,and comparative measurements at the same pressures were performed with the i...
Keywords:iCare Rebound Tonometer  Intraocular pressure  Mice  Correlation  
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