| Taxiphyllin:苦竹笋中具有酪氨酸酶抑制活性的氰苷 |
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| 引用本文： | 程科军,陈竞,梁高林,姚慧,林惠芬,魏少敏,杨君,胡昌奇.Taxiphyllin:苦竹笋中具有酪氨酸酶抑制活性的氰苷[J].天然产物研究与开发,2005,17(6):733-735,772. |
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| 作者姓名： | 程科军 陈竞 梁高林 姚慧 林惠芬 魏少敏 杨君 胡昌奇 |
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| 作者单位： | 1. 复旦大学药学院,上海,200032
2. 上海家化联合股份有限公司,上海,200056 |
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| 摘 要： | 从苦竹笋Pleioblastus amarus（Keng）Keng f．中首次分得一个氰苷化合物，通过光谱分析及其物理化学性质鉴定为taxiphyllin（1）。该化合物在体外能显著抑制酪氨酸酶活性，是一个强有效的酪氨酸酶抑制剂。
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| 关 键 词： | 苦竹笋 taxiphyllin 氰苷 酪氨酸酶 |
| 收稿时间： | 2004-12-27 |
| 修稿时间： | 2004-12-272005-01-31 |
Taxiphyllin:A Cyanogenic Glucoside with Tyrosinase Inhibitory Activity from the Shoots of Pleioblastus amarus |
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| CHENG Ke-jun,CHEN Jing,LIANG Gao-lin,YAO Hui,LIN Hui-fen,WEI Shao-min,YANG Jun,HU Chang-qi.Taxiphyllin:A Cyanogenic Glucoside with Tyrosinase Inhibitory Activity from the Shoots of Pleioblastus amarus[J].Natural Product Research and Development,2005,17(6):733-735,772. |
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| Authors: | CHENG Ke-jun CHEN Jing LIANG Gao-lin YAO Hui LIN Hui-fen WEI Shao-min YANG Jun HU Chang-qi |
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| Institution: | 1. School of Pharmacy, Fudan University, Shanghai 200032, China; 2. Shanghai Jahwa Urdted Co., Ltd., Shanghai 200056, China |
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| Abstract: | A cyanogenic glycoside,taxiphyllin (1),was isolated from the shoots of Pleioblastus amarus (Keng) Keng f.for the first time.It's structure was elucidated on the basis of spectroscopic analysis (UV,IR,MS,1D and 2D NMR) and physiochemical properties.Taxiphyllin was found to inhibit tyrosinase activity in vitro significantly and considered to be a potent tyrosinase inhibitor. |
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| Keywords: | Pleioblastus amarus taxiphyllin cyanogenic glucoside tyrosinase |
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